Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Andre J. Marozsan"'
Autor:
Jean-Philippe Julien, Devin Sok, Reza Khayat, Jeong Hyun Lee, Katie J Doores, Laura M Walker, Alejandra Ramos, Devan C Diwanji, Robert Pejchal, Albert Cupo, Umesh Katpally, Rafael S Depetris, Robyn L Stanfield, Ryan McBride, Andre J Marozsan, James C Paulson, Rogier W Sanders, John P Moore, Dennis R Burton, Pascal Poignard, Andrew B Ward, Ian A Wilson
Publikováno v:
PLoS Pathogens, Vol 9, Iss 5, p e1003342 (2013)
New broad and potent neutralizing HIV-1 antibodies have recently been described that are largely dependent on the gp120 N332 glycan for Env recognition. Members of the PGT121 family of antibodies, isolated from an African donor, neutralize ∼70% of
Externí odkaz:
https://doaj.org/article/46450d10678a451e8c9cef3aada64a58
Autor:
Gregory L Peterfreund, Lee E Vandivier, Rohini Sinha, Andre J Marozsan, William C Olson, Jun Zhu, Frederic D Bushman
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46966 (2012)
Antibiotic disruption of the intestinal microbiota may cause susceptibility to pathogens that is resolved by progressive bacterial outgrowth and colonization. Succession is central to ecological theory but not widely documented in studies of the vert
Externí odkaz:
https://doaj.org/article/633eafe0460a4fdeac4da4441b058c68
Autor:
Cleo G Anastassopoulou, Andre J Marozsan, Alexandre Matet, Amy D Snyder, Eric J Arts, Shawn E Kuhmann, John P Moore
Publikováno v:
PLoS Pathogens, Vol 3, Iss 6, p e79 (2007)
Fitness is a parameter used to quantify how well an organism adapts to its environment; in the present study, fitness is a measure of how well strains of human immunodeficiency virus type 1 (HIV-1) replicate in tissue culture. When HIV-1 develops res
Externí odkaz:
https://doaj.org/article/96c2514afa774e0aac42b2f29bf3eb83
Autor:
Albert Cupo, Jeong Hyun Lee, Ronald Derking, Michael J. Caulfield, Andre J. Marozsan, Simon Hoffenberg, C. Richter King, Rogier W. Sanders, John P. Moore, Per Johan Klasse, Andrew B. Ward, Charles D. Murin, Ian A. Wilson, Jean-Philippe Julien
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 110(11), 213-218. National Academy of Sciences
PG9 is the founder member of an expanding family of glycan-dependent human antibodies that preferentially bind the HIV (HIV-1) envelope (Env) glycoprotein (gp) trimer and broadly neutralize the virus. Here, we show that a soluble SOSIP.664 gp140 trim
Autor:
Robert Pejchal, Rafael S. Depetris, Albert Cupo, William C. Olson, Jeong Hyun Lee, John P. Moore, Rogier W. Sanders, Nicolette Cocco, Jean-Philippe Julien, Milind Kachare, Reza Khayat, Evan Massi, Kathryn B. David, Andre J. Marozsan, Ian A. Wilson, Umesh Katpally, Andrew B. Ward
Publikováno v:
Journal of biological chemistry, 287(29), 24239-24254. American Society for Biochemistry and Molecular Biology Inc.
The trimeric envelope glycoprotein complex (Env) is the focus of vaccine development programs aimed at generating protective humoral responses to human immunodeficiency virus type 1 (HIV-1). N-Linked glycans, which constitute almost half of the molec
Publikováno v:
Journal of Virology. 81:8258-8269
Natural polymorphisms in the heterogeneous human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein may have an impact on both sensitivity to entry inhibitors and viral replicative fitness. Of significant interest is variation in the V3 crow
Autor:
Andre J. Marozsan, Amy Snyder, Thomas J. Ketas, Steven M. Wolinsky, Shawn E. Kuhmann, Pavel Pugach, Joann M. Taylor, John P. Moore, Bette T. Korber
Publikováno v:
Virology. 321:8-22
Primary strains of human immunodeficiency virus type 1 (HIV-1) are known to adapt to replication in cell lines in vitro by becoming sensitive to soluble CD4 (sCD4) and neutralizing antibodies (NAb). T-cell lines favor isolation of variants that use C
Autor:
Michael G. Murray, Nathalie Richard, Tatsuyoshi Kawamura, Sarah C. Ball, Heather A Baird, Andre J. Marozsan, Awet Abraha, Adam Penn-Nicholson, Peter A. Zimmerman, Eric J. Arts, Andrew Blauvelt, Kalonji R. Collins, Michael A. Lobritz, Miguel E. Quiñones-Mateu
Publikováno v:
Journal of Virology. 77:1021-1038
Continual human immunodeficiency virus type 1 (HIV-1) evolution and expansion within the human population have led to unequal distribution of HIV-1 group M subtypes. In particular, recent outgrowth of subtype C in southern Africa, India, and China ha
Autor:
Awet Abraha, Yong Gao, Miguel E. Quiñones-Mateu, Eric J. Arts, Andre J. Marozsan, Sarah C. Ball
Publikováno v:
Journal of Virology. 76:9600-9613
The increased prevalence of human immunodeficiency virus type 1 (HIV-1) intersubtype recombinants (ISRs) is shaping HIV-1 evolution throughout the world and will have an impact on both therapeutic and vaccine strategies. This study was designed to ge
Autor:
Jamie L. Albright, Vincent S. Torre, Sarah C. Ball, Miguel E. Quiñones-Mateu, Andre J. Marozsan, Guido van der Groen, Eric J. Arts, Robert Colebunders, Guido Vanham
Publikováno v:
Journal of virology
This study was designed to examine the impact of human immunodeficiency virus type 1 (HIV-1) fitness on disease progression through the use of a dual competition/heteroduplex tracking assay (HTA). Despite numerous studies on the impact of HIV-1 diver