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pro vyhledávání: '"Andre Hansbauer"'
Autor:
Gregor P. Lotz, Achim Lutz, Meret Martin-Facklam, Andre Hansbauer, Eginhard Schick, Ekkehard Moessner, Michael Antony, Thomas Stuchly, Maria Viert, Ralf J. Hosse, Anne Freimoser-Grundschober, Christian Klein, Martin Schäfer, Mirko Ritter, Kay-Gunnar Stubenrauch
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
An appropriately designed pharmacokinetic (PK) assay that is sensitive for anti-drug antibody (ADA) impact on relevant exposure is an alternative strategy to understand the neutralizing potential of ADAs. However, guidance on how to develop such PK a
Externí odkaz:
https://doaj.org/article/18341a26efd34158ae91f7ef9c0ff3f2
Autor:
Ulrich Essig, Astrid Koehler, Uwe Wessels, Julia Heinrich, Harald Waltenberger, Kay Stubenrauch, Rudolf Vogel, Andre Hansbauer
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 102
Bispecific monoclonal IgG antibodies offer increased efficacy by antagonizing two different targets. Assessing drug mechanisms, target engagement and biomarker features, the quantification of free target levels is essential. The anti-Ang2/VEGF-CrossM