Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andre Gohr"'
Autor:
Demian Burguera, Yamile Marquez, Claudia Racioppi, Jon Permanyer, Antonio Torres-Méndez, Rosaria Esposito, Beatriz Albuixech-Crespo, Lucía Fanlo, Ylenia D’Agostino, Andre Gohr, Enrique Navas-Perez, Ana Riesgo, Claudia Cuomo, Giovanna Benvenuto, Lionel A. Christiaen, Elisa Martí, Salvatore D’Aniello, Antonietta Spagnuolo, Filomena Ristoratore, Maria Ina Arnone, Jordi Garcia-Fernàndez, Manuel Irimia
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Epithelial-mesenchymal interplays are essential to many ontogenetic processes in vertebrates. Here Burguera et al. show diverse embryonic morphogenetic processes regulated by Epithelial Splicing Regulatory Protein (Esrp) in different deuterostome spe
Externí odkaz:
https://doaj.org/article/830be10456764dd28853ccfcc12fd83b
Autor:
Juan Pablo Fernandez, Miguel Angel Moreno-Mateos, Andre Gohr, Liyun Miao, Shun Hang Chan, Manuel Irimia, Antonio J Giraldez
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007473 (2018)
Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome-wide splicing patterns are complex and primarily regulated by a diverse set of recognition elements and associated RNA-binding proteins. The retention and splicing (
Externí odkaz:
https://doaj.org/article/84d58dd44a234c86bf9ea82121c29a58
Although splicing occurs largely co-transcriptionally, the order by which introns are removed does not necessarily follow the order in which they are transcribed. Whereas several genomic features are known to influence whether or not an intron is spl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1f9a20b36118ba81a878035c0e1f364
https://doi.org/10.1101/2022.08.15.503947
https://doi.org/10.1101/2022.08.15.503947
Autor:
Timothy P. Hughes, Hong Zheng, Gregor Rot, Debashish Ray, Quaid Morris, Demian Burguera, Thomas Spruce, Manuel Irimia, Marta Miret, Mara Dierssen, Mireya Plass, Andre Gohr, Ana Nóvoa, Jon Permanyer, Moisés Mallo, María Martínez de Lagrán, Barbara Pernaute, Maurice S. Swanson
Understanding the regulatory interactions that control gene expression during the development of novel tissues is a key goal of evolutionary developmental biology. Here, we show that Mbnl3 has undergone a striking process of evolutionary specializati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156e9db4133688631866527976993058
https://doi.org/10.1101/2021.09.08.459166
https://doi.org/10.1101/2021.09.08.459166
Autor:
Manuel Irimia, Ozren Bogdanovic, Goyeneche L, Bonnal S, Barbara Pernaute, Wyatt Cdr, Rovira Q, Miret-Cuesta M, Andre Gohr
The transition from maternal to embryonic transcriptional control is a crucial step in embryogenesis. However, how alternative splicing is regulated during this process and how it contributes to early development is unknown. Using transcriptomic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a7aa6340adbdd4043dc545c08eeec70
https://doi.org/10.1101/2020.11.25.397794
https://doi.org/10.1101/2020.11.25.397794
Autor:
Andre Gohr, Miguel A. Moreno-Mateos, Antonio J. Giraldez, Manuel Irimia, Juan P. Fernandez, Shun Hang Chan
Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome-wide splicing patterns are complex and primarily regulated by a diverse set of recognition elements and associated RNA-binding proteins. The retention and splicing (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b873279aebe42bacc05a549c8e9f29
https://doi.org/10.1101/197939
https://doi.org/10.1101/197939
Autor:
Manuel Irimia, Reza Sodaei, Teresa Rayon, Mathieu Quesnel-Vallières, Luca Cozzuto, Xinchen Wang, Jon Permanyer, Antonio Hermoso-Pulido, Julia Ponomarenko, Benjamin J. Blencowe, Yamile Marquez, Timothy Sterne-Weiler, Ulrich Braunschweig, Miguel Manzanares, Andre Gohr, Melisa Gomez-Velazquez, Javier Tapial, Kevin C.H. Ha
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Genome Research
Instituto de Salud Carlos III (ISCIII)
Genome Research
Alternative splicing (AS) generates remarkable regulatory and proteomic complexity in metazoans. However, the functions of most AS events are not known, and programs of regulated splicing remain to be identified. To address these challenges, we descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772c9ea6c743a84426c692376c5b17f5
http://hdl.handle.net/20.500.12105/10491
http://hdl.handle.net/20.500.12105/10491
Autor:
Ifeanyi Jude Ezeonwumelu, Edurne García-Vidal, Eudald Felip, Maria C. Puertas, Bruna Oriol-Tordera, Lucía Gutiérrez-Chamorro, André Gohr, Marta Ruiz-Riol, Marta Massanella, Bonaventura Clotet, Javier Martinez-Picado, Roger Badia, Eva Riveira-Muñoz, Ester Ballana
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The persistence of latent HIV reservoirs allows for viral rebound upon antiretroviral therapy interruption, hindering effective HIV-1 cure. Emerging evidence suggests that modulation of innate immune stimulation could impact viral latency and contrib
Externí odkaz:
https://doaj.org/article/0c134c9371f546d1bf28e34f8645f39a
Autor:
Thomas Spruce, Mireya Plass, André Gohr, Debashish Ray, María Martínez de Lagrán, Gregor Rot, Ana Nóvoa, Demian Burguera, Jon Permanyer, Marta Miret, Hong Zheng, Maurice S Swanson, Quaid Morris, Moises Mallo, Mara Dierssen, Timothy R Hughes, Barbara Pernaute, Manuel Irimia
Publikováno v:
PLoS Biology, Vol 20, Iss 4, p e3001615 (2022)
Understanding the regulatory interactions that control gene expression during the development of novel tissues is a key goal of evolutionary developmental biology. Here, we show that Mbnl3 has undergone a striking process of evolutionary specializati
Externí odkaz:
https://doaj.org/article/123842fa9e434a1097df0caff61e1e6d
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Several families of natural compounds target core components of the pre-mRNA splicing machinery and display anti-tumor activity. Here the authors show that particular sequence features can be linked to drug response, and that drugs with very similar
Externí odkaz:
https://doaj.org/article/51214b9023cc455398337408c0f8b445