Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Andre G Tempone"'
Autor:
Geanne A Alves Conserva, Luis M Quirós-Guerrero, Thais A Costa-Silva, Laurence Marcourt, Erika G Pinto, Andre G Tempone, João Paulo S Fernandes, Jean-Luc Wolfender, Emerson F Queiroz, João Henrique G Lago
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247334 (2021)
EtOH extracts from the leaves and twigs of Nectandra oppositifolia Nees & Mart. shown activity against amastigote forms of Trypanosoma cruzi. These extracts were subjected to successive liquid-liquid partitioning to afford bioactive CH2Cl2 fractions.
Externí odkaz:
https://doaj.org/article/28fee4cc4c4f4c10a111249964cad818
Autor:
Simone S Grecco, Thais A Costa-Silva, Fernanda S Sousa, Stefano B Cargnelutti, Eric Umehara, Poliana S Mendonça, Andre G Tempone, Joao Henrique G Lago
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 1, Pp 1-7 (2018)
Abstract Background The therapeutic arsenal for the treatment of Leishmaniasis is limited and includes toxic compounds (antimonials, amphotericin B, pentamidine and miltefosine). Given these aspects, the search for new compounds based on floristic bi
Externí odkaz:
https://doaj.org/article/5bf6d7d8675745a798591aac3e75d532
Autor:
Erika G Pinto, Isabela O Santos, Thomas J Schmidt, Samanta E T Borborema, Vitor F Ferreira, David R Rocha, Andre G Tempone
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105127 (2014)
Naphtoquinones have been used as promising scaffolds for drug design studies against protozoan parasites. Considering the highly toxic and limited therapeutic arsenal, the global negligence with tropical diseases and the elevated prevalence of co-mor
Externí odkaz:
https://doaj.org/article/cac26f38f07f4b648c9a4a4e8086cffd
Autor:
Ana Sozanschi, Hannah Asiki, Maiara Amaral, Erica V. de Castro Levatti, Andre G. Tempone, Richard J. Wheeler, Edward A. Anderson
Publikováno v:
JACS Au, Vol 4, Iss 2, Pp 847-854 (2024)
Externí odkaz:
https://doaj.org/article/b6904fda2d804baa967c9d21cd530c74
Autor:
Alexandre Rea, Andre G Tempone, Erika G Pinto, Juliana T Mesquita, Eliana Rodrigues, Luciana Grus M Silva, Patricia Sartorelli, João Henrique G Lago
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 12, p e2556 (2013)
Chagas disease is caused by the parasitic protozoan Trypanosoma cruzi. It has high mortality as well as morbidity rates and usually affects the poorer sections of the population. The development of new, less harmful and more effective drugs is a prom
Externí odkaz:
https://doaj.org/article/686c41552dce40098b09ea231e2cbad1
Autor:
Matheus L. Silva, Felipe S. Sales, Erica V. C. Levatti, Guilherme M. Antar, Andre G. Tempone, João Henrique G. Lago, Gerold Jerz
Publikováno v:
Molecules, Vol 29, Iss 1, p 212 (2023)
Endemic in 21 countries, Chagas disease, also known as American Trypanosomiasis, is a neglected tropical disease (NTD) caused by the protozoan parasite Trypanosoma cruzi. The available drugs for the treatment of this disease, benznidazole and nifurti
Externí odkaz:
https://doaj.org/article/db14e826885d4677b2e6cfeaa51f20b6
Publikováno v:
Saudi Pharmaceutical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7db733d7d32fb1312696cd3ecde86113
https://doi.org/10.1016/j.jsps.2023.05.014
https://doi.org/10.1016/j.jsps.2023.05.014
Autor:
Maiara Amaral, Marina T. Varela, Ravi Kant, Myron Christodoulides, João Paulo S. Fernandes, Andre G. Tempone
Publikováno v:
Life
Volume 13
Issue 3
Pages: 663
Volume 13
Issue 3
Pages: 663
Chagas disease is an endemic tropical disease caused by the protozoan Trypanosoma cruzi, which affects around 7 million people worldwide, mostly in development countries. The treatment relies on only two available drugs, with severe adverse effects a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e127c3660449ab9be2c665556bd6896d
Autor:
Maiara Amaral, Hannah Asiki, Claire E. Sear, Snigdha Singh, Pauline Pieper, Marius M Haugland, Edward A. Anderson, Andre G Tempone
Publikováno v:
RSC Medicinal Chemistry.
Visceral leishmaniasis is a neglected protozoan disease with high mortality. Existing treatments exhibit a number of limitations, resulting in a significant challenge for public health, especially in developing countries in...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d708e665de4357367df9de263222f22d
https://doi.org/10.1039/d3md00081h
https://doi.org/10.1039/d3md00081h
Autor:
Mayara M. Luiz, Isabele R. Nascimento, Andre G. Tempone, Mayra F. Costa, Leonardo C. de Souza, João Henrique G. Lago
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-28T19:44:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef960c1084a652a8aca56ab9e0b19b73
https://doi.org/10.1016/j.phytol.2021.09.003
https://doi.org/10.1016/j.phytol.2021.09.003