Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andre Fouquet"'
Autor:
Pierre Lacasse, R. Berthiaume, André Robichaud, Andre Fouquet, Franca Beraldin, S.I. Borucki Castro
Publikováno v:
Journal of Dairy Science. 94:4684-4689
In a previous study, milk iodine concentration from 501 farms across Canada was found to vary considerably and appeared to be influenced by feeding practices. Farms with contrasting levels of milk iodine from a subset of 200 participating farms were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c09b95223b13181e5bda25b47b2d3a
https://doi.org/10.3168/jds.2010-3714
https://doi.org/10.3168/jds.2010-3714
Publikováno v:
Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Lead (Pb), cadmium (Cd) and aluminum (Al) were determined in 437 individual samples of infant formulae, oral electrolytes and 5% glucose solutions available in Canada. In the electrolytes, Cd and Pb concentrations were all below 0.01 and 0.041 ng g(-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b024708b336bac839a00c1357c4f2c5
https://doi.org/10.1080/19393210.2011.571795
https://doi.org/10.1080/19393210.2011.571795
Autor:
Josephine Deeks, Franca Beraldin, André Robichaud, Andre Fouquet, Stephane Turcotte, Genevieve Clement, J. Bertrand, Guy Dufresne, L. Bilodeau
Publikováno v:
Journal of Food Composition and Analysis. 24:441-448
In order to generate new data for vitamin D content for the Canadian Nutrient File, a method for the quantification of vitamin D3 and 25(OH)D3 in foodstuffs has been modified and improved. Vitamin D3 was quantified using reverse phase liquid chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b30d30853b0cc50b95e134ed53faf1b
https://doi.org/10.1016/j.jfca.2010.08.002
https://doi.org/10.1016/j.jfca.2010.08.002
Autor:
Hortense Deronzier, Cecile Dorleans, John Waller, Laurent Saniere, Andre Fouquet, Fiona Elizabeth Andrews, Mark Baugh, J.C.M. Uitdehaag, George McGarry, Phil Jones, Ann Mitchell, Emma Kinghorn, Eric Nicolai, Wilson Caulfield, Zoran Rankovic, Dominique Potin, Mario van Zeeland, Wullie Arbuckle, Jennifer Kerr, Jiaqiang Cai, Mark Wheaton Anderson, Iain Martin, Maureen Dempster, Ashvin Mistry, François Chevallier, William Finlay, Clive Long, Robinson John E, Xavier Fradera, Paul Westwood, Iain Cumming
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6237-6241
Several structure-guided optimisation strategies were explored in order to improve the hERG selectivity profile of cathepsin K inhibitor 1 , whilst maintaining its otherwise excellent in vitro and in vivo profile. Ultimately, attenuation of c log P a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcfb747e700da9944dc50d293047fcc
https://doi.org/10.1016/j.bmcl.2010.08.101
https://doi.org/10.1016/j.bmcl.2010.08.101
Autor:
Eric Nicolai, Clive Long, Ann Mitchell, Maureen Dempster, William Hamilton, Jennifer Kerr, Cecile Dorleans, Iain Martin, Paul Scullion, Hortense Deronzier, John Bruin, Emma Hamilton, Zoran Rankovic, Andre Fouquet, John Robinson, John Waller, Laurent Saniere, Mark Baugh, Fiona Andrews, Jiaqiang Cai, Joost C.M. Uitdehaag, Wilson Caulfield, Dominique Potin, Ashvin Mistry, François Chevallier, Paul Westwood, Emma Kinghorn, George McGarry, Iain Cumming, Mario van Zeeland, X. Fradera
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:1524-1527
Morphing structural features of HTS-derived chemotypes led to the discovery of novel 2-cyano-pyrimidine inhibitors of cathepsin K with good pharmacokinetic profiles, for example, compound 20 showed high catK potency (IC(50)=4nM), >580-fold selectivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3024221a3f1580ea5f971d2c310f2b7
https://doi.org/10.1016/j.bmcl.2010.01.100
https://doi.org/10.1016/j.bmcl.2010.01.100
Autor:
Andre Fouquet, Sue C. Quade, Dorothea F. K. Rawn, Wing-Fung Sun, André Bélanger, Mark R. Smith
Publikováno v:
Journal of Agricultural and Food Chemistry. 56:916-921
Apples were sampled directly from orchard trees at 96, 45, and 21 days postapplication with one of three organophosphate insecticides (azinphos methyl, phosalone, or phosmet, respectively). Individual apples were prepared for analysis following one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c186d586d4d86867ccf36e3dba47731
https://doi.org/10.1021/jf072408m
https://doi.org/10.1021/jf072408m
Autor:
Iain Cumming, Andre Fouquet, Hortense Deronzier, Mark Baugh, William Finlay, Emma Kinghorn, Zoran Rankovic, Jiaqiang Cai, Eric Nicolai, Maureen Dempster, Mario van Zeeland, François Chevallier, Jennifer Kerr, Sylviane Boucharens, George McGarry, William Hamilton, Xavier Fradera, J.C.M. Uitdehaag, Robinson John E, Laurent Saniere, Dominique Potin, Jonathan Gillespie, John Bruin, Paul Scullion, D. Jonathan Bennett, Cecile Dorleans, Kenneth S. Cameron
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(15)
Starting from previously disclosed equally potent cathepsin K and S inhibitor 4-propyl-6-(3-trifluoromethylphenyl)pyrimidine-2-carbonitrile 1, a novel 2-phenyl-9H-purine-6-carbonitrile scaffold was identified to provide potent and selective cathepsin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98bd55a43ebd81843ae171f54be9d64
https://pubmed.ncbi.nlm.nih.gov/20594841
https://pubmed.ncbi.nlm.nih.gov/20594841
Autor:
Andre Fouquet, A. Cloarec, Daniel Provost, Jean Marie Charles Teulon, Timur Gungor, Michele Cazes
Publikováno v:
Journal of Medicinal Chemistry. 35:4455-4463
Novel 2-arylbenzimidazoles and azabenzimidazoles were synthesized, and their inotropic action was evaluated. Changes in left ventricular pressure, dP/dt max, were measured as an index of cardiac contractility. The structural features that impart opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00d300e63679791e550ac56e53fa283
https://doi.org/10.1021/jm00101a024
https://doi.org/10.1021/jm00101a024
Autor:
Giacomo Conca, Mark Smith, Andre Fouquet, André Bélanger, Sue C. Quade, Dorothea F. K. Rawn, Wing-Fung Sun, J Brian Shields, Gladys M. A. Lacroix
Publikováno v:
Food additives and contaminants. 24(2)
Apple trees in an orchard in Quebec, Canada were treated, following label directions, with the fungicide captan (1,2,3,6-tetrahydro-N-(trichloromethylthio)phthalimide) during the 2003 agricultural season. A total of 142 apples from three rows of tree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f197b7a394a746889eaf50429f73804
https://pubmed.ncbi.nlm.nih.gov/17364915
https://pubmed.ncbi.nlm.nih.gov/17364915
Autor:
Dominique, Potin, Michele, Launay, Francoise, Monatlik, Patrice, Malabre, Maud, Fabreguettes, Andre, Fouquet, Magali, Maillet, Eric, Nicolai, Loïc, Dorgeret, François, Chevallier, Dominique, Besse, Monique, Dufort, François, Caussade, Syed Z, Ahmad, Dawn K, Stetsko, Stacey, Skala, Patricia M, Davis, Praveen, Balimane, Karishma, Patel, Zheng, Yang, Punit, Marathe, Jennifer, Postelneck, Robert M, Townsend, Valentina, Goldfarb, Steven, Sheriff, Howard, Einspahr, Kevin, Kish, Mary F, Malley, John D, DiMarco, Jack Z, Gougoutas, Pathanjali, Kadiyala, Daniel L, Cheney, Ravindra W, Tejwani, Denette K, Murphy, Kim W, Mcintyre, Xiaoxia, Yang, Sam, Chao, Leslie, Leith, Zili, Xiao, Arvind, Mathur, Bang-Chi, Chen, Daugh-Rurng, Wu, Sarah C, Traeger, Murray, McKinnon, Joel C, Barrish, Jeffrey A, Robl, Edwin J, Iwanowicz, Suzanne J, Suchard, T G Murali, Dhar
Publikováno v:
Journal of medicinal chemistry. 49(24)
LFA-1 (leukocyte function-associated antigen-1), is a member of the beta2-integrin family and is expressed on all leukocytes. This letter describes the discovery and preliminary SAR of spirocyclic hydantoin based LFA-1 antagonists that culminated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::678c8cc3816580fa1740622533be39a5
https://pubmed.ncbi.nlm.nih.gov/17125246
https://pubmed.ncbi.nlm.nih.gov/17125246