Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Andre Fedier"'
Publikováno v:
Metabolites, Vol 2, Iss 4, Pp 913-939 (2012)
Glycans are important partners in many biological processes, including carcinogenesis. The rapidly developing field of functional glycomics becomes one of the frontiers of biology and biomedicine. Aberrant glycosylation of proteins and lipids occurs
Externí odkaz:
https://doaj.org/article/902e6a82c043463f83af4f0c04a809a0
Autor:
Viola Heinzelmann-Schwarz, Claudia Lengerke, Nicolle H. Packer, Monica Nunez Lopez, Andreas Schötzau, Andre Fedier, Natalie Rimmer, Yen-Lin Huang, Arun V. Everest-Dass, Reto S. Kohler, Ching-Yeu Liang, Martina Konantz, Shahidul Alam, Francis Jacob
This file contains: Supplementary material & methods Supplementary Figure S1 Globoside GSL synthesizing glycosyltransferases show elevated gene expression in epithelial tissue samples. Supplementary Figure S2 EMT marker gene expression in 47 ovarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6baf82fed250df71f8d901de608d34e6
https://doi.org/10.1158/0008-5472.22417022.v1
https://doi.org/10.1158/0008-5472.22417022.v1
Autor:
Francesco Vigo, Alessandra Tozzi, Muriel Disler, Vasileios Kavvadias, Andre Fedier, Viola Heinzelmann-Schwarz, Tilemachos Kavvadias
Publikováno v:
Translational research/biomarkers.
Autor:
Alessandra Tozzi, Muriel Disler, Ricardo Coelho, Flavio Lombardo, Andre Fedier, Monica Nunez Lopez, Florian Freuler, Francis Jacob, Viola Heinzelmann-Schwarz
Publikováno v:
Translational research/biomarkers.
Autor:
Kathrin B. Labrosse, Flavio C. Lombardo, Natalie Rimmer, Mónica Núñez López, André Fedier, Viola Heinzelmann-Schwarz, Ricardo Coelho, Francis Jacob
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103274- (2024)
Summary: Three-dimensional (3D) ex vivo cultures allow the study of cancer progression and drug resistance mechanisms. Here, we present a protocol for measuring on-target drug sensitivity in a scaffold-free 3D culture system through quantification of
Externí odkaz:
https://doaj.org/article/7878e94092734d8e99c5e69881ee4ebf
Autor:
Cécile Cumin, Yen-Lin Huang, Charlotte Rossdam, Felix Ruoff, Susana Posada Céspedes, Ching-Yeu Liang, Flavio C. Lombardo, Ricardo Coelho, Natalie Rimmer, Martina Konantz, Mónica Núñez López, Shahidul Alam, Alexander Schmidt, Diego Calabrese, Andre Fedier, Tatjana Vlajnic, Mark von Itzstein, Markus Templin, Falk F.R. Buettner, Arun Everest-Dass, Viola Heinzelmann-Schwarz, Francis Jacob
Publikováno v:
Cell reports. 40(7)
The molecular repertoire promoting cancer cell plasticity is not fully elucidated. Here, we propose that glycosphingolipids (GSLs), specifically the globo and ganglio series, correlate and promote the transition between epithelial and mesenchymal cel
Autor:
Fabienne D. Schwab, Manuel C. Scheidmann, Lauren L. Ozimski, André Kling, Lucas Armbrecht, Till Ryser, Ilona Krol, Karin Strittmatter, Bich Doan Nguyen-Sträuli, Francis Jacob, André Fedier, Viola Heinzelmann-Schwarz, Andreas Wicki, Petra S. Dittrich, Nicola Aceto
Publikováno v:
Microsystems & Nanoengineering, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Cancer patients with advanced disease are characterized by intrinsic challenges in predicting drug response patterns, often leading to ineffective treatment. Current clinical practice for treatment decision-making is commonly based on primar
Externí odkaz:
https://doaj.org/article/bf251c3a1c404b639047bcf71de7b3ad
Autor:
Ricardo Coelho, Alessandra Tozzi, Muriel Disler, Flavio Lombardo, André Fedier, Mónica Núñez López, Florian Freuler, Francis Jacob, Viola Heinzelmann-Schwarz
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-13 (2022)
Abstract PARP inhibitors (PARPi) have revolutionized the therapeutic landscape of epithelial ovarian cancer (EOC) treatment with outstanding benefits in regard to progression-free survival, especially in patients either carrying BRCA1/2 mutations or
Externí odkaz:
https://doaj.org/article/dc5ab75700d94ee09c33c23ff0a4a4ac
Autor:
Yen-Lin Huang, Ching-Yeu Liang, Danilo Ritz, Ricardo Coelho, Dedy Septiadi, Manuela Estermann, Cécile Cumin, Natalie Rimmer, Andreas Schötzau, Mónica Núñez López, André Fedier, Martina Konantz, Tatjana Vlajnic, Diego Calabrese, Claudia Lengerke, Leonor David, Barbara Rothen-Rutishauser, Francis Jacob, Viola Heinzelmann-Schwarz
Publikováno v:
eLife, Vol 9 (2020)
The extracellular matrix (ECM) plays critical roles in tumor progression and metastasis. However, the contribution of ECM proteins to early metastatic onset in the peritoneal cavity remains unexplored. Here, we suggest a new route of metastasis throu
Externí odkaz:
https://doaj.org/article/1d428aa47c2f4db9a039680fd8b80d54
Autor:
Céline Montavon Sartorius, Andreas Schoetzau, Henriette Kettelhack, Daniel Fink, Neville F Hacker, André Fedier, Francis Jacob, Viola Heinzelmann-Schwarz
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0195213 (2018)
The relationship between ABO blood groups (BG) and risk of incidence in cancers including gynecological cancers has been widely studied, showing increased incidence risk for BG A patients. As available data are inconsistent we investigated whether BG
Externí odkaz:
https://doaj.org/article/232f9b0bf3844763856f701e77ff312b