Evidence for action of ribavirin through the hepatitis C virus RNA polymerase

Autor: A. M. Di Bisceglie, John E. Tavis, Andre C. Lyra, Nathan A. Cannon, Maureen J. Donlin, L. M. Mayes

Publikováno v: Journal of Viral Hepatitis. 16:595-604

Hepatitis C virus (HCV) infections are treated with interferon alpha plus ribavirin, but it is unknown how ribavirin works against HCV. Ribavirin is a guanosine analogue that can be a substrate for the viral RNA polymerase. HCV is genetically variabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7edbc9d086f0d297038b0659186528e7
https://doi.org/10.1111/j.1365-2893.2009.01109.x

Seroprevalence and risk factors associated with Helicobacter pylori infection in blood donors in Salvador, Northeast-Brazil

Autor: Andre C. Lyra, Genoile Santana, Nelma Santana, Anibal Silvany-Neto, Emilia Magalhães, Eduardo M. Pereira, Ramiro Mascarenhas, Marcos C. Lyra, Andrea Veiga, Karina Ferreira, Schilioma Zaterka, Luiz G. Lyra

Publikováno v: Brazilian Journal of Infectious Diseases, Vol 7, Iss 5, Pp 339-345

Helicobacter pylori plays an important role in the etiology of peptic ulcer disease. Its prevalence appears to be higher in developing countries. We evaluated the seroprevalence of H. pylori and risk factors associated with infection in voluntary blo

Externí odkaz: https://doaj.org/article/a00bf05c451741d2a16453c567b16699

Distribution of hepatitis B virus (HBV) genotypes among patients with acute viral hepatitis

Autor: Andre C, Lyra, João Rr, Pinho, Isabel M V G C, Mello, Fernanda, de M Malta, Michele M S, Gomes, Adrian M, Di Bisceglie, Luiz G C, Lyra, Flair J, Carrilho, Luiz C, da Silva

Publikováno v: Journal of clinical gastroenterology. 39(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2af002ef8ee0eb422a6188ab4767f40e
https://pubmed.ncbi.nlm.nih.gov/15599222

CD81 binding regions of hepatitis C virus remain conserved after liver transplantation

Autor: Andre C. Lyra, Xiaofeng Fan, Adrian M. Di Bisceglie

Publikováno v: Brazilian Journal of Infectious Diseases v.8 n.2 2004
Brazilian Journal of Infectious Diseases
Brazilian Society of Infectious Diseases (BSID)
instacron:BSID
Brazilian Journal of Infectious Diseases, Volume: 8, Issue: 2, Pages: 126-132, Published: APR 2004
Brazilian Journal of Infectious Diseases, Vol 8, Iss 2, Pp 126-132

CD81 is a surface-associated protein expressed in the membranes of mammalian cells. It has been suggested that CD81 interacts with hepatitis C virus E2 protein, and thus might facilitate the entry of HCV into hepatocytes. The envelope-binding site ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b621f55e26b7b26580bb8e877e4c4ab4
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000200002

Liver transplantation with hepatitis C virus-infected graft: interaction between donor and recipient viral strains

Autor: Andre C. Lyra, Dorothy Lang, James E. Everhart, Yanjuan Xu, Alan S. Perelson, Karina Yusim, Xiaofeng Fan, Bette T. Korber, Adrian M. Di Bisceglie

Publikováno v: Hepatology (Baltimore, Md.). 38(1)

Superinfection of different viral strains within a single host provides an opportunity for studying host-virus and virus-virus interactions, including viral interference and genetic recombination, which cannot be studied in infections with single vir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0720e7ddc8bead8eb8d9d7eaf67bfa
https://pubmed.ncbi.nlm.nih.gov/12829983