Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Andre Bongers"'
Publikováno v:
Advanced Science, Vol 10, Iss 9, Pp n/a-n/a (2023)
Abstract Antibody‐nanoparticle conjugates are promising candidates for precision medicine. However, developing a controllable method for conjugating antibodies to nanoparticles without compromising the antibody activity represents a critical challe
Externí odkaz:
https://doaj.org/article/d5515f22b1c64c7aacfd1bffab7c3330
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280498 (2023)
Early neuropathology mechanisms in neurodevelopmental disorders are partially understood because routine anatomical magnetic resonance imaging (MRI) cannot detect subtle brain microstructural changes in vivo during postnatal development. Therefore, w
Externí odkaz:
https://doaj.org/article/e9ae3c038cb046d7af0c5f6a335ec4a3
Autor:
Marina Ulanova, Lucy Gloag, Andre Bongers, Chul-Kyu Kim, Hong Thien Kim Duong, Ha Na Kim, John Justin Gooding, Richard D. Tilley, Joanna Biazik, Wei Wen, Perminder S. Sachdev, Nady Braidy
Publikováno v:
Cells, Vol 12, Iss 18, p 2279 (2023)
Nanoparticle-based magnetic contrast agents have opened the potential for magnetic resonance imaging (MRI) to be used for early non-invasive diagnosis of Alzheimer’s disease (AD). Accumulation of amyloid pathology in the brain has shown association
Externí odkaz:
https://doaj.org/article/7c99c76be6ca41ac9467dbcc147b8274
Autor:
Dominik Fröhlich, Elizabeth Kalotay, Georg von Jonquieres, Andre Bongers, Brendan Lee, Alexandra K. Suchowerska, Gary D. Housley, Matthias Klugmann
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The leukodystrophy Canavan disease is a fatal white matter disorder caused by loss-of-function mutations of the aspartoacylase-encoding ASPA gene. There are no effective treatments available and experimental gene therapy trials have failed to provide
Externí odkaz:
https://doaj.org/article/537c8c0bb7154f5697810c52b8705019
Autor:
Dominik Fröhlich, Marisa I. Mendes, Andrew J. Kueh, Andre Bongers, Marco J. Herold, Gajja S. Salomons, Gary D. Housley, Matthias Klugmann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2021)
Hypomyelination with brain stem and spinal cord involvement and leg spasticity (HBSL) is a leukodystrophy caused by missense mutations of the aspartyl-tRNA synthetase-encoding gene DARS1. The clinical picture includes the regression of acquired motor
Externí odkaz:
https://doaj.org/article/2a471b43f5584d4da9624c90395f5e86
Autor:
Xiaoting Lin, Fengying Tang, Shouyuan Jiang, Heba Khamis, Andre Bongers, John M. Whitelock, Megan S. Lord, Jelena Rnjak‐Kovacina
Publikováno v:
Advanced Science, Vol 7, Iss 17, Pp n/a-n/a (2020)
Abstract Angiogenic therapy involving delivery of pro‐angiogenic growth factors to stimulate new blood vessel formation in ischemic disease is promising but has seen limited clinical success due to issues associated with the need to deliver supra
Externí odkaz:
https://doaj.org/article/7997ac02c53b49728f497391ca390a70
Autor:
Dominik Fröhlich, Alexandra K. Suchowerska, Ziggy H.T. Spencer, Georg von Jonquieres, Claudia B. Klugmann, Andre Bongers, Fabien Delerue, Holly Stefen, Lars M. Ittner, Thomas Fath, Gary D. Housley, Matthias Klugmann
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 24-35 (2017)
Background: The recently diagnosed leukodystrophy Hypomyelination with Brain stem and Spinal cord involvement and Leg spasticity (HBSL) is caused by mutations of the cytoplasmic aspartyl-tRNA synthetase gene DARS. The physiological role of DARS in tr
Externí odkaz:
https://doaj.org/article/39cbdf69bfe24fa787ad07522d5df957
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148652 (2016)
Understanding neural injury in hydrocephalus and how the brain changes during the course of the disease in-vivo remain unclear. This study describes brain deformation, microstructural and mechanical properties changes during obstructive hydrocephalus
Externí odkaz:
https://doaj.org/article/a64b4feca9a3498b9fd2036318cd2c39
Autor:
Annika van Hummel, Mian Bi, Stefania Ippati, Julia van der Hoven, Alexander Volkerling, Wei S Lee, Daniel C S Tan, Andre Bongers, Arne Ittner, Yazi D Ke, Lars M Ittner
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163236 (2016)
Several mouse lines with knockout of the tau-encoding MAPT gene have been reported in the past; they received recent attention due to reports that tau reduction prevented Aβ-induced deficits in mouse models of Alzheimer's disease. However, the effec
Externí odkaz:
https://doaj.org/article/198cf4797f2446478f1e11dbaa23fa88
Autor:
Matthias Klugmann, Elizabeth Kalotay, Fabien Delerue, Lars M. Ittner, Andre Bongers, Josephine Yu, Margaret J. Morris, Gary D. Housley, Dominik Fröhlich
Publikováno v:
Neurochemical Research. 47:1985-1990