Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Andre Bazzone"'
Autor:
Manan Bhatt, Laure Gauthier-Manuel, Erika Lazzarin, Rocco Zerlotti, Christine Ziegler, Andre Bazzone, Thomas Stockner, Elena Bossi
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system (CNS). Its homeostasis is maintained by neuronal and glial GABA transporters (GATs). The four GATs identified in humans are GAT1 (SLC6A1), GAT2 (SLC6
Externí odkaz:
https://doaj.org/article/122f346d4f684060bcd6969a55da141f
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Beside the ongoing efforts to determine structural information, detailed functional studies on transporters are essential to entirely understand the underlying transport mechanisms. We recently found that solid supported membrane-based electrophysiol
Externí odkaz:
https://doaj.org/article/178f20480b6a406a873dec9c69792ff3
Autor:
Andre Bazzone, Maria Barthmes, Cecilia George, Nina Brinkwirth, Rocco Zerlotti, Valentin Prinz, Kim Cole, Søren Friis, Alexander Dickson, Simon Rice, Jongwon Lim, May Fern Toh, Milad Mohammadi, Davide Pau, David J. Stone, John J. Renger, Niels Fertig
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12788 (2023)
The lysosomal cation channel TMEM175 is a Parkinson’s disease-related protein and a promising drug target. Unlike whole-cell automated patch-clamp (APC), lysosomal patch-clamp (LPC) facilitates physiological conditions, but is not yet suitable for
Externí odkaz:
https://doaj.org/article/625d07dbeb7d49aabc9de970d2e33891
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156392 (2016)
Bacterial sugar symporters in the Major Facilitator Superfamily (MFS) use the H+ (and in a few cases Na+) electrochemical gradients to achieve active transport of sugar into the cell. Because a number of structures of MFS sugar symporters have been s
Externí odkaz:
https://doaj.org/article/1931cb7e20264ad9bc8500f26913829f
Autor:
Rei Matsuoka, Roman Fudim, Sukkyeong Jung, Chenou Zhang, Andre Bazzone, Yurie Chatzikyriakidou, Carol V. Robinson, Norimichi Nomura, So Iwata, Michael Landreh, Laura Orellana, Oliver Beckstein, David Drew
Publikováno v:
Nature Structural & Molecular Biology. 30:565-565
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d27ecf88a0bc98a81c98c37a38fea98
https://doi.org/10.1038/s41594-023-00970-4
https://doi.org/10.1038/s41594-023-00970-4
Publikováno v:
Biophysical Journal. 122:398a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d54343ba2140d98ac3baba0a000205f
https://doi.org/10.1016/j.bpj.2022.11.2173
https://doi.org/10.1016/j.bpj.2022.11.2173
Publikováno v:
The Journal of Biological Chemistry
Bacterial transporters are difficult to study using conventional electrophysiology because of their low transport rates and the small size of bacterial cells. Here, we applied solid-supported membrane–based electrophysiology to derive kinetic param
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173ab5f163d13e9c80e23eacd2a83eef
http://europepmc.org/articles/PMC8784342
http://europepmc.org/articles/PMC8784342
Autor:
Rei Matsuoka, Norimichi Nomura, David A. Drew, Chenou Zhang, Oliver Beckstein, Sukkyeong Jung, Yurie Chatzikyriakidou, Roman Fudim, Laura Orellana, So Iwata, Andre Bazzone
Na+/H+ exchangers catalyse an ion-exchange activity that is carried out in most, if not all cells. SLC9B2, also known as NHA2, correlates with the long-sought after sodium/lithium (Na+/Li+) exchanger linked to the pathogenesis of diabetes mellitus an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d31fad3fc2f2ec244eb080a0f4a5f7b
https://doi.org/10.1101/2021.07.22.453398
https://doi.org/10.1101/2021.07.22.453398
Autor:
Rei, Matsuoka, Roman, Fudim, Sukkyeong, Jung, Chenou, Zhang, Andre, Bazzone, Yurie, Chatzikyriakidou, Carol V, Robinson, Norimichi, Nomura, So, Iwata, Michael, Landreh, Laura, Orellana, Oliver, Beckstein, David, Drew
Publikováno v:
Nature structuralmolecular biology. 29(2)
The Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c38278bc1a4a107eb10eee768209aee2
https://pubmed.ncbi.nlm.nih.gov/35173351
https://pubmed.ncbi.nlm.nih.gov/35173351
Autor:
Andre, Bazzone, Maria, Barthmes
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2168
Here, we present a protocol for the functional characterization of the H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e594a3b2a8d2b1dfccabf37f918819f1
https://pubmed.ncbi.nlm.nih.gov/33582988
https://pubmed.ncbi.nlm.nih.gov/33582988