Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andre A F L, van Puijenbroek"'
Autor:
Jos B Poell, Rick J van Haastert, Thijs de Gunst, Iman J Schultz, Willemijn M Gommans, Mark Verheul, Francesco Cerisoli, Andre A F L van Puijenbroek, Paula I van Noort, Gregoire P Prevost, Roel Q J Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE, Vol 8, Iss 1 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0043569.].
Externí odkaz:
https://doaj.org/article/809690cb2b36494aae39d53295789ec4
Autor:
Jos B Poell, Rick J van Haastert, Thijs de Gunst, Iman J Schultz, Willemijn M Gommans, Mark Verheul, Francesco Cerisoli, Andre A F L van Puijenbroek, Paula I van Noort, Gregoire P Prevost, Roel Q J Schaapveld, Edwin Cuppen
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Externí odkaz:
https://doaj.org/article/d40c736567e848e5920930dd9625597e
Autor:
Andre A. F. L. van Puijenbroek, Esther M. Lafuente, Alla Berezovskaya, Timothy A. Springer, Christopher V. Carman, Erica Constantine, Gordon J. Freeman, Matthias Krause, Vassiliki A. Boussiotis, Frank B. Gertler
Publikováno v:
Developmental Cell. 7(4):585-595
The small GTPase Rap1 induces integrin-mediated adhesion and changes in the actin cytoskeleton. The mechanisms that mediate these effects of Rap1 are poorly understood. We have identified RIAM as a Rap1-GTP-interacting adaptor molecule. RIAM defines
Autor:
Dimitrios Tzachanis, Alla Berezovskaya, Andre A. F. L. van Puijenbroek, Lee M. Nadler, Leonard Joseph Appleman, Vassiliki A. Boussiotis
Publikováno v:
The Journal of Immunology. 171:1691-1696
Anergy is a state of immunologic tolerance in which T cells are viable but incapable of responding to antigenic stimulation. Recent data indicate that anergic cells have a distinct gene expression program that determines their unique function. In thi
Publikováno v:
Blood. 101:998-1006
Cyclic adenosine monophosphate (cAMP) is a negative regulator of T-cell activation. However, the effects of cAMP on signaling pathways that regulate cytokine production and cell cycle progression remain unclear. Here, using primary human T lymphocyte
Autor:
Jos B, Poell, Rick J, van Haastert, Thijs, de Gunst, Iman J, Schultz, Willemijn M, Gommans, Mark, Verheul, Francesco, Cerisoli, Andre A F L, van Puijenbroek, Paula I, van Noort, Gregoire P, Prevost, Roel Q J, Schaapveld, Edwin, Cuppen
Publikováno v:
PLoS ONE
PLoS One, 7(8). Public Library of Science
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
PLoS One, 7(8). Public Library of Science
PLoS ONE, Vol 7, Iss 8, p e43569 (2012)
Malignant melanoma is an aggressive form of skin cancer with poor prognosis. Despite improvements in awareness and prevention of this disease, its incidence is rapidly increasing. MicroRNAs (miRNAs) are a class of small RNA molecules that regulate ce
Autor:
Thomas Grader-Beck, Andre A. F. L. van Puijenbroek, Vassiliki A. Boussiotis, Leonard Joseph Appleman, Dimitrios Tzachanis
Publikováno v:
Scopus-Elsevier
The ability to achieve complete hematopoietic engraftment in the allogeneic setting without intensive myeloablative chemotherapy will have a profound effect on the practice of allogeneic hematopoietic cell transplantation (HCT). Novel methods to indu
Autor:
Vassiliki A. Boussiotis, Leonard Joseph Appleman, Kirstin M. Shu, Lee M. Nadler, Andre A. F. L. van Puijenbroek
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 168(6)
CD28 provides a costimulatory signal that cooperates with the TCR/CD3 complex to induce T cell activation, cytokine production, and clonal expansion. We have recently shown that CD28 directly regulates progression of T lymphocytes through the cell cy
Autor:
Michael W. Delfs, Vassiliki A. Boussiotis, Naoto Hirano, Dimitrios Tzachanis, Lee M. Nadler, Gordon J. Freeman, Andre A. F. L. van Puijenbroek, Alla Berezovskaya
Publikováno v:
Nature immunology. 2(12)
During a search for genes that maintain T cell quiescence, we determined that Tob, a member of an anti-proliferative gene family, was highly expressed in anergic T cell clones. Tob was also expressed in unstimulated peripheral blood T lymphocytes and
Autor:
Vassiliki A. Boussiotis, Dimitrios Tzachanis, Thomas Grader-Beck, Leonard Joseph Appleman, Andre A. F. L. van Puijenbroek
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 78(12)
Tolerance in vivo and its in vitro counterpart, anergy, are defined as the state in which helper T lymphocytes are alive but incapable of producing IL-2 and expanding in response to optimal antigenic stimulation. Anergy is induced when the T cell rec