Zobrazeno 1 - 10
of 231
pro vyhledávání: '"André Pèlegrin"'
Autor:
Emilia Rabia, Véronique Garambois, Christine Dhommée, Christel Larbouret, Laurie Lajoie, Yoan Buscail, Gabriel Jimenez-Dominguez, Sylvie Choblet-Thery, Emmanuelle Liaudet-Coopman, Martine Cerutti, Marta Jarlier, Patrice Ravel, Laurent Gros, Nelly Pirot, Gilles Thibault, Eugene A. Zhukovsky, Pierre-Emmanuel Gérard, André Pèlegrin, Jacques Colinge, Thierry Chardès
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The ErbB family of receptor tyrosine kinases is a primary target for small molecules and antibodies for pancreatic cancer treatment. Nonetheless, the current treatments for this tumor are not optimal due to lack of efficacy, resistance, or toxicity.
Externí odkaz:
https://doaj.org/article/8a10b603d78a414f85898e71f788257b
Autor:
Maëva Chauvin, Véronique Garambois, Pierre-Emmanuel Colombo, Myriam Chentouf, Laurent Gros, Jean-Paul Brouillet, Bruno Robert, Marta Jarlier, Karen Dumas, Pierre Martineau, Isabelle Navarro-Teulon, David Pépin, Thierry Chardès, André Pèlegrin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract In ovarian carcinoma, anti-Müllerian hormone (AMH) type II receptor (AMHRII) and the AMH/AMHRII signaling pathway are potential therapeutic targets. Here, AMH dose-dependent effect on signaling and proliferation was analyzed in four ovarian
Externí odkaz:
https://doaj.org/article/3bb1d01d694a4347845bf86dc683698e
Autor:
Jérôme Lacombe, Muriel Brengues, Alain Mangé, Céline Bourgier, Sophie Gourgou, André Pèlegrin, Mahmut Ozsahin, Jérôme Solassol, David Azria
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-11 (2019)
Abstract Background Biomarkers for predicting late normal tissue toxicity to radiotherapy are necessary to personalize treatments and to optimize clinical benefit. Many radiogenomic studies have been published on this topic. Conversely, proteomics ap
Externí odkaz:
https://doaj.org/article/6467dd72a28346129ffe48e7196fef29
Autor:
Christophe Le Clorennec, Yassamine Lazrek, Olivier Dubreuil, Carla Sampaio, Christel Larbouret, Romain Lanotte, Marie-Alix Poul, Jean-Marc Barret, Jean-François Prost, André Pèlegrin, Thierry Chardès
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background HER3/ErbB3 receptor deletion or blockade leads to tumor cell apoptosis, whereas its overexpression confers anti-cancer drug resistance through upregulation of protective mechanisms against apoptosis. We produced the anti-HER3 anti
Externí odkaz:
https://doaj.org/article/4b70fcb461494809aa475152be331389
Autor:
Yahya Ashraf, Hanane Mansouri, Valérie Laurent-Matha, Lindsay B. Alcaraz, Pascal Roger, Séverine Guiu, Danielle Derocq, Gautier Robin, Henri-Alexandre Michaud, Helène Delpech, Marta Jarlier, Martine Pugnière, Bruno Robert, Anthony Puel, Lucie Martin, Flavie Landomiel, Thomas Bourquard, Oussama Achour, Ingrid Fruitier-Arnaudin, Alexandre Pichard, Emmanuel Deshayes, Andrei Turtoi, Anne Poupon, Joëlle Simony-Lafontaine, Florence Boissière-Michot, Nelly Pirot, Florence Bernex, William Jacot, Stanislas du Manoir, Charles Theillet, Jean-Pierre Pouget, Isabelle Navarro-Teulon, Nathalie Bonnefoy, André Pèlegrin, Thierry Chardès, Pierre Martineau, Emmanuelle Liaudet-Coopman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Background Triple-negative breast cancer (TNBC) treatment is currently restricted to chemotherapy. Hence, tumor-specific molecular targets and/or alternative therapeutic strategies for TNBC are urgently needed. Immunotherapy is emerging as a
Externí odkaz:
https://doaj.org/article/29cfb2cf1cb546cb9c2f21a1f397c343
Autor:
Bérénice Framery, Marian Gutowski, Karen Dumas, Alexandre Evrard, Nathalie Muller, Vincent Dubois, Jérôme Quinonero, François Scherninski, André Pèlegrin, Françoise Cailler
Publikováno v:
Toxicology Reports, Vol 6, Iss , Pp 409-415 (2019)
The real-time improvement of the intraoperative discrimination between different tissue types (particularly between tumor and adjacent normal tissue) using intraoperative imaging represents a considerable advance for oncology surgeons. However, the d
Externí odkaz:
https://doaj.org/article/c73e0e9844304d9397132dc4f5b5b56e
Autor:
Emilia Rabia, Véronique Garambois, Julie Hubert, Marine Bruciamacchie, Nelly Pirot, Hélène Delpech, Morgane Broyon, Charles Theillet, Pierre-Emmanuel Colombo, Nadia Vie, Diego Tosi, Celine Gongora, Lakhdar Khellaf, Marta Jarlier, Nina Radosevic-Robin, Thierry Chardès, André Pèlegrin, Christel Larbouret
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Chemoresistance, particularly to gemcitabine, is a major challenge in pancreatic cancer. The epidermal growth factor receptor (EGFR) and human epidermal growth factor receptors 2 and 3 (HER2, HER3) are expressed in many tumors, and they are relevant
Externí odkaz:
https://doaj.org/article/321dae94e99e49a6a55ffcb4d608277f
Autor:
Daniel Baty, Jean-Luc Teillaud, Patrick Chames, André Pèlegrin, Bruno Robert, Brigitte Kerfelec, Charlotte Boix, Ghislaine Behar, Martine Chartier, Corinne Pétiard, Amélie Cornillon, Caroline Rozan
PDF file - 60K, Lack of competition between bsFab and human IgG for FcγRIIIa binding.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cca666b6c70b795ecbb7f15043ac786
https://doi.org/10.1158/1535-7163.22499808
https://doi.org/10.1158/1535-7163.22499808
Autor:
Thierry Chardès, André Pèlegrin, Jean-François Prost, Gérard Mathis, Jean-Marc Barret, Philippe Mondon, Marie-Alix Poul, Véronique Garambois, Yassamine Lazrek, Charline Ogier, Christel Larbouret, Olivier Dubreuil, Hervé Bazin, Christophe Le Clorennec
Supplemental Fig.S3. In pancreatic cancer cells, ch9F7-F11-Emb is a negative allosteric modulator of NRG1-mediated signaling. The low-fucose non-NRG1 competing allosteric anti-HER3 antibody ch9F7-F11-Emb inhibits in a dose-dependent manner NRG1-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6f44107aaead5130a42c31d8cfc79
https://doi.org/10.1158/1535-7163.22503252.v1
https://doi.org/10.1158/1535-7163.22503252.v1
Autor:
Daniel Baty, Jean-Luc Teillaud, Patrick Chames, André Pèlegrin, Bruno Robert, Brigitte Kerfelec, Charlotte Boix, Ghislaine Behar, Martine Chartier, Corinne Pétiard, Amélie Cornillon, Caroline Rozan
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6118553ab49972b705e04f2af9747754
https://doi.org/10.1158/1535-7163.22499805.v1
https://doi.org/10.1158/1535-7163.22499805.v1