Role of molecular adsorbent recirculating system in methotrexate-induced acute liver failure: a case report and literature review

Autor: T. Corbisier, André O. Von Bueren, W.B. Breunis, S. Grazioli

Publikováno v: Frontiers in Pediatrics, Vol 12 (2024)

We describe the case of a 14-year-old girl with osteosarcoma who was treated with high-dose methotrexate (12 g/m2). Twenty-four hours after the infusion, her plasma methotrexate concentration was elevated at 937 μmol/L (normal

Externí odkaz: https://doaj.org/article/631484f4c1184253ae5faa8ece8a5960

Pediatric Posterior Fossa ATRT: A Case Report, New Treatment Strategies and Perspectives

Autor: Luca Paun, Alexandre Lavé, Gianpaolo Jannelli, Kristof Egervari, Insa Janssen, Karl Schaller, André O. von Bueren, Andrea Bartoli

Publikováno v: Brain Sciences, Vol 13, Iss 5, p 712 (2023)

Posterior fossa atypical teratoid rhabdoid tumor (ATRT) is a rare childhood tumor usually associated with a dismal prognosis. Although upfront surgical gross total resection (GTR) has classically been the first line of treatment, new multimodal treat

Externí odkaz: https://doaj.org/article/003ac971e1c14998ade2b953f4548124

Concurrent IDH1 and SMARCB1 Mutations in Pediatric Medulloblastoma: A Case Report

Autor: Moatasem El-Ayadi, Kristof Egervari, Doron Merkler, Thomas A. McKee, Fabienne Gumy-Pause, Damian Stichel, David Capper, Torsten Pietsch, Marc Ansari, André O. von Bueren

Publikováno v: Frontiers in Neurology, Vol 9 (2018)

Isocitrate Dehydrogenase-1 (IDH1) is a driver gene in several cancers including brain tumors such as low-grade and high-grade gliomas. Mutations of SMARCB1 were described in atypical teratoid rhabdoid tumors and to date have not been associated with

Externí odkaz: https://doaj.org/article/723858f03d954a54ab7cb0336e1c1e68

Data from The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

Autor: Olaf Witt, Stefan M. Pfister, David Capper, Jan J. Molenaar, David T.W. Jones, Annette Kopp-Schneider, Peter Lichter, Ruth Witt, Angelika Freitag, Uta Dirksen, Andreas von Deimling, Felix Sahm, David Reuss, Stephan Wolf, Natalie Jäger, Till Milde, C. Michel Zwaan, Bianca Goemans, Maria Filippidou, Antonis Kattamis, Bernarda Kazanowska, Olli Lohi, Nicolas U. Gerber, Caroline Hutter, Ingrid Øra, Roman Tremmel, Matthias Schwab, Simone Hettmer, Monika Scheer, Michael T. Meister, Ewa Koscielniak, Simone Fulda, Petra Ketteler, Ines B. Brecht, Dominik T. Schneider, Michael C. Frühwald, Stefanie Hecker-Nolting, Michaela Nathrath, Wilhelm Wößmann, Birgit Burkhardt, Angelika Eggert, Matthias Fischer, Frank Westermann, Norbert Graf, Peter Vorwerk, Gabriele Calaminus, André O. von Bueren, Christof M. Kramm, Irene Schmid, Dietrich von Schweinitz, Stephan Tippelt, Gudrun Fleischhack, Jan-Henning Klusmann, Dirk Reinhardt, Roland Meisel, Arndt Borkhardt, Andrej Lissat, Andreas E. Kulozik, Arend von Stackelberg, Kerstin Grund, Christian Sutter, Steffen Hirsch, Nicola Dikow, Kathrin Schramm, Mirjam Blattner-Johnson, Pascal D. Johann, Sebastian Stark, Gnana Prakash Balasubramanian, Barbara C. Jones, Petra Fiesel, Karin P.S. Langenberg, Kristian W. Pajtler, Elke Pfaff, Cornelis M. van Tilburg

INFORM is a prospective, multinational registry gathering clinical and molecular data of relapsed, progressive, or high-risk pediatric patients with cancer. This report describes long-term follow-up of 519 patients in whom molecular alterations were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff21fae7f2dbec73c8ce658d2e5de67
https://doi.org/10.1158/2159-8290.c.6549356.v1

Supplementary Figure from The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

Autor: Olaf Witt, Stefan M. Pfister, David Capper, Jan J. Molenaar, David T.W. Jones, Annette Kopp-Schneider, Peter Lichter, Ruth Witt, Angelika Freitag, Uta Dirksen, Andreas von Deimling, Felix Sahm, David Reuss, Stephan Wolf, Natalie Jäger, Till Milde, C. Michel Zwaan, Bianca Goemans, Maria Filippidou, Antonis Kattamis, Bernarda Kazanowska, Olli Lohi, Nicolas U. Gerber, Caroline Hutter, Ingrid Øra, Roman Tremmel, Matthias Schwab, Simone Hettmer, Monika Scheer, Michael T. Meister, Ewa Koscielniak, Simone Fulda, Petra Ketteler, Ines B. Brecht, Dominik T. Schneider, Michael C. Frühwald, Stefanie Hecker-Nolting, Michaela Nathrath, Wilhelm Wößmann, Birgit Burkhardt, Angelika Eggert, Matthias Fischer, Frank Westermann, Norbert Graf, Peter Vorwerk, Gabriele Calaminus, André O. von Bueren, Christof M. Kramm, Irene Schmid, Dietrich von Schweinitz, Stephan Tippelt, Gudrun Fleischhack, Jan-Henning Klusmann, Dirk Reinhardt, Roland Meisel, Arndt Borkhardt, Andrej Lissat, Andreas E. Kulozik, Arend von Stackelberg, Kerstin Grund, Christian Sutter, Steffen Hirsch, Nicola Dikow, Kathrin Schramm, Mirjam Blattner-Johnson, Pascal D. Johann, Sebastian Stark, Gnana Prakash Balasubramanian, Barbara C. Jones, Petra Fiesel, Karin P.S. Langenberg, Kristian W. Pajtler, Elke Pfaff, Cornelis M. van Tilburg

Supplementary Figure from The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87241d6487fda7eea0b9f69782d2a059
https://doi.org/10.1158/2159-8290.22540361.v1