Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Andre, Wolterbeek"'
Publikováno v:
Archives of Toxicology
Since teratogenicity testing in mammals is a particular challenge from an animal welfare perspective, there is a great need for the development of alternative test systems. In this context, the zebrafish (Danio rerio) embryo has received increasing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d5d1cd5f9fca1bcfb343b738950c20
Autor:
Erik Hansen, Freddy Van Goethem, Natalie Mesens, Peter de Witte, Camila V. Esguerra, Jacky Van Gompel, Rik Nuyts, Alexander D. Crawford, Pham Duc Hung, Andre Wolterbeek, Aswin Menke
Publikováno v:
Journal of Applied Toxicology. 35:1017-1029
Drug-induced liver injury (DILI) is poorly predicted by single-cell-based assays, probably because of the lack of physiological interactions with other cells within the liver. An intact whole liver system such as one present in zebrafish larvae could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2dad8b5133a0708172f7e3f79ee8694
https://doi.org/10.1002/jat.3091
https://doi.org/10.1002/jat.3091
Autor:
Andre Wolterbeek, Ine D.H. Waalkens-Berendsen, Didima de Groot, André Penninks, Henk Van Loveren, Elisa C.M. Tonk, Aldert H. Piersma
Publikováno v:
Archives of Toxicology, 87(2), 323-335. Springer
The susceptibility of developing immune system to chemical disruption warrants the assessment of immune parameters in reproductive and developmental testing protocols. In this study, a wide range of immune endpoints was included in an extended one-ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ceb42e231d0dfee6563d4d380e7ad9
https://doi.org/10.1007/s00204-012-0940-1
https://doi.org/10.1007/s00204-012-0940-1
Publikováno v:
Neurotoxicology and Teratology. 34:545-553
The zebrafish is a powerful toxicity model; biochemical assays can be combined with observations at a structural and functional level within one individual. This mini review summarises the potency of zebrafish as a model for developmental neurotoxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab4e26000866fa34f3d300360126c2dd
https://doi.org/10.1016/j.ntt.2012.08.006
https://doi.org/10.1016/j.ntt.2012.08.006
Autor:
Maaike Van Zijverden, Mariska Tegelenbosch-Schouten, C. Frieke Kuper, Carlijn Klaassen, Andre Wolterbeek
Publikováno v:
Toxicologic Pathology, 2, 35, 226-232
The effects of cyclosporin A (CY) and cyclophosphamide (CPS) on Peyer's patches (PP) were studied in Wistar rats, exposed in utero and neonatally or during adult age. In one study, pregnant dams received 5 or 15 mg/kg bw/day CY from gestation day 6 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b1303b08f6dce53da44f92d6752476
https://doi.org/10.1080/01926230601156245
https://doi.org/10.1080/01926230601156245
Autor:
Bennard van Ravenzwaay, Steffen Schneider, Han van de Sandt, Thomas Hofmann, Robert Landsiedel, Andre Wolterbeek
Publikováno v:
Reproductive Toxicology, 56, 141–146
Synthetic amorphous silica is a nanostructured material, which is produced and used in a wide variety of technological applications and consumer products. No regulatory prenatal toxicity studies with this substance were reported yet. Therefore, synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148f5b2f0fdb5250c77102b949db33a1
http://resolver.tudelft.nl/uuid:fedc4983-62e4-4a9e-9fb2-9529061e6da2
http://resolver.tudelft.nl/uuid:fedc4983-62e4-4a9e-9fb2-9529061e6da2
Autor:
F.J. van de Brug, E.P. van Someren, T. Rouhani Rankouhi, Frieke Kuper, Simon Folkertsma, Cyrille Krul, Lars Verschuren, Jennifer Venhorst, Andre Wolterbeek
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 81:352-353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc3d66692885d35106012a8596a8955
https://doi.org/10.1016/j.vascn.2016.02.059
https://doi.org/10.1016/j.vascn.2016.02.059
Autor:
Natalie, Mesens, Alexander D, Crawford, Aswin, Menke, Pham Duc, Hung, Freddy, Van Goethem, Rik, Nuyts, Erik, Hansen, Andre, Wolterbeek, Jacky, Van Gompel, Peter, De Witte, Camila V, Esguerra
Publikováno v:
Journal of applied toxicology : JAT. 35(9)
Drug-induced liver injury (DILI) is poorly predicted by single-cell-based assays, probably because of the lack of physiological interactions with other cells within the liver. An intact whole liver system such as one present in zebrafish larvae could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da324d271ee797649283b97cc0e47f12
https://pubmed.ncbi.nlm.nih.gov/25663337
https://pubmed.ncbi.nlm.nih.gov/25663337
Autor:
Aldert H. Piersma, Emiel Rorije, Sander C. van der Linden, Hai-Yen Man, Harrie Buist, B. Pieterse, Inge Mangelsdorf, Bart van der Burg, Andre Wolterbeek, Geertje Lewin, Barbara M.A. van Vugt-Lussenburg, E. Dinant Kroese
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 55
There is a great need for alternative testing methods for reproductive toxicants that are practical, fast, cost-effective and easy to interpret. Previously we followed a pragmatic approach using readily available tests, which was successful in predic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbce3bbd2db96b7b89a6ddba17894baf
https://pubmed.ncbi.nlm.nih.gov/25527862
https://pubmed.ncbi.nlm.nih.gov/25527862
Autor:
V.J. de Groot, Mark Bogaart, Andor Veltien, Marijana Radonjic, Andre Wolterbeek, E. F. J. de Vries, L. Linders, R. Kayser, Rianne Nederlof, D. M. G. de Groot, Frieke Kuper, Arend Heerschap
Publikováno v:
Reproductive Toxicology, 48, pp. 12-13
Reproductive Toxicology, 48, 12-13
Reproductive Toxicology, 48, 12-13
Item does not contain fulltext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd52fbd647175efb45371cb0079d06b7
https://doi.org/10.1016/j.reprotox.2014.07.003
https://doi.org/10.1016/j.reprotox.2014.07.003