Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Andre, Obenaus"'
Autor:
Tetyana Chumak, Amandine Jullienne, C. Joakim Ek, Maryam Ardalan, Pernilla Svedin, Ryan Quan, Arjang Salehi, Sirus Salari, Andre Obenaus, Zinaida S Vexler, Carina Mallard
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Infection during the perinatal period can adversely affect brain development, predispose infants to ischemic stroke and have lifelong consequences. We previously demonstrated that diet enriched in n-3 polyunsaturated fatty acids (n-3 PUFA) t
Externí odkaz:
https://doaj.org/article/171dee11aa984a618f77b1c77a287ac0
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-19 (2024)
Abstract Traumatic brain injury (TBI) survivors face debilitating long-term psychosocial consequences, including social isolation and depression. TBI modifies neurovascular physiology and behavior but the chronic physiological implications of altered
Externí odkaz:
https://doaj.org/article/031af4a27fcb41dfa03f963b34f4fc26
Autor:
Perla Ontiveros-Ángel, Julio David Vega-Torres, Timothy B. Simon, Vivianna Williams, Yaritza Inostroza-Nives, Nashareth Alvarado-Crespo, Yarimar Vega Gonzalez, Marjory Pompolius, William Katzka, John Lou, Fransua Sharafeddin, Ike De la Peña, Tien Dong, Arpana Gupta, Chi T. Viet, Marcelo Febo, Andre Obenaus, Aarti Nair, Johnny D. Figueroa
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100879- (2024)
Childhood overweight/obesity is associated with stress-related psychopathology, yet the pathways connecting childhood obesity to stress susceptibility are poorly understood. We employed a systems biology approach with 62 adolescent Lewis rats fed a W
Externí odkaz:
https://doaj.org/article/9fea0a7f67e344abb8da0296a06a3374
Autor:
Jaclyn Iannucci, Reagan Dominy, Shreya Bandopadhyay, E. Madison Arthur, Brenda Noarbe, Amandine Jullienne, Margret Krkasharyan, Richard P. Tobin, Aleksandr Pereverzev, Samantha Beevers, Lavanya Venkatasamy, Karienn A. Souza, Daniel C. Jupiter, Alan Dabney, Andre Obenaus, M. Karen Newell-Rogers, Lee A. Shapiro
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-24 (2024)
Abstract Background Traumatic brain injury (TBI) is a significant risk factor for Alzheimer’s disease (AD), and accumulating evidence supports a role for adaptive immune B and T cells in both TBI and AD pathogenesis. We previously identified B cell
Externí odkaz:
https://doaj.org/article/7fbfabe044294bf4bcec2f591179eada
Autor:
Nicolas G. Bazan, Andre Obenaus, Larissa Khoutorova, Pranab K. Mukherjee, Bokkyoo Jun, Rostyslav Semikov, Ludmila Belayev
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2555 (2024)
Background: In the United States, traumatic brain injury (TBI) contributes significantly to mortality and morbidity. Elovanoids (ELVs), a novel class of homeostatic lipid mediators we recently discovered and characterized, have demonstrated neuroprot
Externí odkaz:
https://doaj.org/article/01fc51d5ea8644eba3905677b8c18984
Autor:
Madigan M. Reid, Ludmila Belayev, Larissa Khoutorova, Pranab K. Mukherjee, Andre Obenaus, Kierany Shelvin, Stacey Knowles, Sung-Ha Hong, Nicolas G. Bazan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Despite efforts to identify modulatory neuroprotective mechanisms of damaging ischemic stroke cascade signaling, a void remains on an effective potential therapeutic. The present study defines neuroprotection by very long-chain polyunsaturat
Externí odkaz:
https://doaj.org/article/fc704bbd2d7a486596a98cd9c5b843c9
Autor:
Andre Obenaus, Beatriz Rodriguez-Grande, Jeong Bin Lee, Christophe J. Dubois, Marie-Line Fournier, Martine Cador, Stéphanie Caille, Jerome Badaut
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Traumatic brain injury (TBI) has the highest incidence amongst the pediatric population and its mild severity represents the most frequent cases. Moderate and severe injuries as well as repetitive mild TBI result in lasting morbidity. Howeve
Externí odkaz:
https://doaj.org/article/7e142d6a10964dbd93102df8b9824056
Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer’s disease
Autor:
Amandine Jullienne, Jenny I. Szu, Ryan Quan, Michelle V. Trinh, Tannoz Norouzi, Brenda P. Noarbe, Amanda A. Bedwell, Kierra Eldridge, Scott C. Persohn, Paul R. Territo, Andre Obenaus
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionThe 5xFAD mouse is a popular model of familial Alzheimer’s disease (AD) that is characterized by early beta-amyloid (Aβ) deposition and cognitive decrements. Despite numerous studies, the 5xFAD mouse has not been comprehensively phenot
Externí odkaz:
https://doaj.org/article/8ec2a97582564be2a7400ac1d5fb9d6d
Autor:
Xiaoxiao Lin, Lujia Chen, Amandine Jullienne, Hai Zhang, Arjang Salehi, Mary Hamer, Todd C. Holmes, Andre Obenaus, Xiangmin Xu
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-19 (2022)
Abstract Acquired brain injuries due to trauma damage the cortical vasculature, which in turn impairs blood flow to injured tissues. There are reports of vascular morphological recovery following traumatic brain injury, but the remodeling process has
Externí odkaz:
https://doaj.org/article/7ce0eb24d94a412f8b9d6846e9f40e7f
Autor:
Julio David Vega-Torres, Perla Ontiveros-Angel, Esmeralda Terrones, Erwin C. Stuffle, Sara Solak, Emma Tyner, Marie Oropeza, Ike dela Peña, Andre Obenaus, Byron D. Ford, Johnny D. Figueroa
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Childhood obesity leads to hippocampal atrophy and altered cognition. However, the molecular mechanisms underlying these impairments are poorly understood. The neurotrophic factor neuregulin-1 (NRG1) and its cognate ErbB4 receptor play criti
Externí odkaz:
https://doaj.org/article/2ea077aa6d4641659a2713c45f9cced9