Antitubercular Activity Increase in Labdane Diterpenes from Copaifera Oleoresin through Structural Modification

Autor: Silva,Aline N., Soares,Ana Carolina F., Cabral,Mirela M. W., Andrade,Alex R. P. de, Silva,Marilza B. M. da, Martins,Carlos H. G., Veneziani,Rodrigo C. S., Ambrósio,Sérgio R., Bastos,Jairo K., Heleno,Vladimir C. G.

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 28, Issue: 6, Pages: 1106-1112, Published: JUN 2017
Journal of the Brazilian Chemical Society v.28 n.6 2017
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

The labdane diterpenes copalic acid, 3β-acetoxy-copalic acid, 3β-hydroxy-copalic acid and ent-agathic acid were isolated from Copaifera langsdorffii oleoresin. These four compounds were submitted to structural modifications by reduction with hydrog

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