Olaparib tablets as maintenance therapy in patients with platinum-sensitive relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21)

Autor: Andrés Poveda, Anne Floquet, Jonathan A Ledermann, Rebecca Asher, Richard T Penson, Amit M Oza, Jacob Korach, Tomasz Huzarski, Sandro Pignata, Michael Friedlander, Alessandra Baldoni, Tjoung-Won Park-Simon, Kenji Tamura, Gabe S Sonke, Alla Lisyanskaya, Jae-Hoon Kim, Elias Abdo Filho, Tsveta Milenkova, Elizabeth S Lowe, Phil Rowe, Ignace Vergote, Eric Pujade-Lauraine, Tomasz Byrski, Patricia Pautier, Philipp Harter, Nicoletta Colombo, Giovanni Scambia, Maria Nicoletto, Fiona Nussey, Andrew Clamp, Richard Penson, Amit Oza, Andrés Poveda Velasco, Manuel Rodrigues, Jean-Pierre Lotz, Frédéric Selle, Isabelle Ray-Coquard, Diane Provencher, Aleix Prat Aparicio, Laura Vidal Boixader, Clare Scott, Mayu Yunokawa, Jacques Medioni, Nicolas Pécuchet, Coraline Dubot, Thibault De La Motte Rouge, Marie-Christine Kaminsky, Béatrice Weber, Alain Lortholary, Christine Parkinson, Jonathan Ledermann, Sarah Williams, Susana Banerjee, Jonathan Cosin, James Hoffman, Marie Plante, Allan Covens, Gabe Sonke, Florence Joly, Holger Hirte, Amnon Amit, Koji Matsumoto, Sergei Tjulandin, Jae Hoon Kim, Laurence Gladieff, Roberto Sabbatini, David O'Malley, Patrick Timmins, Daniel Kredentser, Nuria Laínez Milagro, Maria Pilar Barretina Ginesta, Ariadna Tibau Martorell, Alfonso Gómez De Liaño Lista, Belén Ojeda González, Linda Mileshkin, Masaki Mandai, Ingrid Boere, Petronella Ottevanger, Joo-Hyun Nam, Elias Filho, Salima Hamizi, Francesco Cognetti, David Warshal, Elizabeth Dickson-Michelson, Scott Kamelle, Nathalie McKenzie, Gustavo Rodriguez, Deborah Armstrong, Eva Chalas, Paul Celano, Kian Behbakht, Susan Davidson, Stephen Welch, Limor Helpman, Ami Fishman, Ilan Bruchim, Magdalena Sikorska, Anna Słowińska, Wojciech Rogowski, Mariusz Bidziński, Beata Śpiewankiewicz, Antonio Casado Herraez, César Mendiola Fernández, Martina Gropp-Meier, Toshiaki Saito, Kazuhiro Takehara, Takayuki Enomoto, Hidemichi Watari, Chel Hun Choi, Byoung-Gie Kim, Jae Weon Kim, Roberto Hegg

Publikováno v: Lancet Oncology, 22, 5, pp. 620-631
Lancet Oncology, 22, 620-631
The Lancet Oncology, 22(5), 620-631. Lancet Publishing Group

Contains fulltext : 241226.pdf (Publisher’s version ) (Closed access) BACKGROUND: Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, has previously been shown to extend progression-free survival versus placebo when given to patients with re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327550b0b53fe7a798b4b4246c0e4f41
https://doi.org/10.1016/s1470-2045(21)00073-5

Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21) : a double-blind, randomised, placebo-controlled, phase 3 trial

Autor: Eric Pujade-Lauraine, Jonathan A Ledermann, Frédéric Selle, Val Gebski, Richard T Penson, Amit M Oza, Jacob Korach, Tomasz Huzarski, Andrés Poveda, Sandro Pignata, Michael Friedlander, Nicoletta Colombo, Philipp Harter, Keiichi Fujiwara, Isabelle Ray-Coquard, Susana Banerjee, Joyce Liu, Elizabeth S Lowe, Ralph Bloomfield, Patricia Pautier, Tomasz Byrski, Giovanni Scambia, Maria Nicoletto, Fiona Nussey, Andrew Clamp, Richard Penson, Amit Oza, Andrés Poveda Velasco, Manuel Rodrigues, Jean-Pierre Lotz, Diane Provencher, Aleix Prat Aparicio, Laura Vidal Boixader, Clare Scott, Kenji Tamura, Mayu Yunokawa, Alla Lisyanskaya, Jacques Medioni, Nicolas Pécuchet, Coraline Dubot, Thibault de la Motte Rouge, Marie-Christine Kaminsky, Béatrice Weber, Alain Lortholary, Christine Parkinson, Jonathan Ledermann, Sarah Williams, Jonathan Cosin, James Hoffman, Marie Plante, Allan Covens, Gabe Sonke, Florence Joly, Anne Floquet, Holger Hirte, Amnon Amit, Tjoung-Won Park-Simon, Koji Matsumoto, Sergei Tjulandin, Jae Hoon Kim, Laurence Gladieff, Roberto Sabbatini, David O'Malley, Patrick Timmins, Daniel Kredentser, Nuria Laínez Milagro, Maria Pilar Barretina Ginesta, Ariadna Tibau Martorell, Alfonso Gómez de Liaño Lista, Belén Ojeda González, Linda Mileshkin, Masaki Mandai, Ingrid Boere, Petronella Ottevanger, Joo-Hyun Nam, Elias Filho, Salima Hamizi, Francesco Cognetti, David Warshal, Elizabeth Dickson-Michelson, Scott Kamelle, Nathalie McKenzie, Gustavo Rodriguez, Deborah Armstrong, Eva Chalas, Paul Celano, Kian Behbakht, Susan Davidson, Stephen Welch, Limor Helpman, Ami Fishman, Ilan Bruchim, Magdalena Sikorska, Anna Słowińska, Wojciech Rogowski, Mariusz Bidziński, Beata Śpiewankiewicz, Antonio Casado Herraez, César Mendiola Fernández, Martina Gropp-Meier, Toshiaki Saito, Kazuhiro Takehara, Takayuki Enomoto, Hidemichi Watari, Chel Hun Choi, Byoung-Gie Kim, Jae Weon Kim, Roberto Hegg, Ignace Vergote

Publikováno v: The Lancet Oncology, 18(9), 1274-1284. Lancet Publishing Group

Background Olaparib, a poly(ADP-ribose) polymerase (PARP) inhibitor, has previously shown efficacy in a phase 2 study when given in capsule formulation to all-comer patients with platinum-sensitive, relapsed high-grade serous ovarian cancer. We aimed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6905acb5cb7386782be1e6d05659ba93
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85025811245

[Third National Ovarian Consensus. 2011. Grupo de Investigación en Cáncer de Ovario y Tumores Ginecológicos de México 'GICOM']

Autor: Dolores, Gallardo-Rincón, David, Cantú-de-León, Patricia, Alanís-López, Miguel Angel, Alvarez-Avitia, Joel, Bañuelos-Flores, Guillermo Sidney, Herbert-Núñez, Luis Fernando, Oñate-Ocaña, María Delia, Pérez-Montiel, Amelia, Rodríguez-Trejo, Eva, Ruvalcaba-Limón, Alberto, Serrano-Olvera, Andrea, Ortega-Rojo, Patricia, Cortés-Esteban, Aura, Erazo-Valle, Raquel, Gerson-Cwilich, Jaime, De-la-Garza-Salazar, Dan, Green-Renner, Eucario, León-Rodríguez, Flavia, Morales-Vásquez, Andrés, Poveda-Velasco, José Luis, Aguilar-Ponce, Luis Felipe, Alva-López, Salvador, Alvarado-Aguilar, Isabel, Alvarado-Cabrero, Cinthia Alejandra, Aquino-Mendoza, Carlos Eduardo, Aranda-Flores, Artfy, Bandera-Delgado, Eduardo, Barragán-Curiel, Patricia, Barrón-Rodríguez, Rocío, Brom-Valladares, Paula Anel, Cabrera-Galeana, Germán, Calderillo-Ruiz, Salvador, Camacho-Gutiérrez, Daniel, Capdeville-García, Jesús, Cárdenas-Sánchez, Elisa, Carlón-Zárate, Oscar, Carrillo-Garibaldi, Gerardo, Castorena-Roji, Guadalupe, Cervantes-Sánchez, Jaime Alberto, Coronel-Martínez, José Gregorio, Chanona-Vilchis, Verónica, Díaz-Hernández, Pedro, Escudero-de-los Ríos, Olga, Garibay-Cerdenares, Eva, Gómez-García, Luis Alonso, Herrera-Montalvo, Luz María, Hinojosa-García, David, Isla-Ortiz, Josefina, Jiménez-López, Arturo Javier, Lavín-Lozano, Jesús Alberto, Limón-Rodriguez, Horacio Noé, López-Basave, Sergio César, López-García, Antonio, Maffuz-Aziz, Jorge, Martínez-Cedillo, Dulce María, Martínez-López, Juan Manuel, Medina-Castro, Carlos, Melo-Martínez, Carmen, Méndez-Herrera, Gonzalo, Montalvo-Esquivel, Miguel Angel, Morales-Palomares, Andrés, Morán-Mendoza, Gilberto, Morgan-Villela, Aída, Mota-García, David Eduardo, Muñoz-González, Francisco J, Ochoa-Carrillo, Maricruz, Pérez-Amador, Edgar, Recinos-Money, Samuel, Rivera-Rivera, Juan U, Robles Flores, Edith, Rojas-Castillo, Carlos, Rojas-Marín, Efraín, Salas-Gonzáles, Liliana, Sámano-Nateras, Miguel, Santibañez-Andrade, Antonio, Santillán-Gómez, Araceli, Silva-García, Juan Alejandro, Silva, Gilberto, Solorza-Luna, Adán Raúl, Tabarez-Ortiz, Patricia, Talamás-Rohana, Laura Leticia, Tirado-Gómez, Alfonso, Torres-Lobatón, Félix, Quijano-Castro

Publikováno v: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. 63(6)

Ovarian cancer (OC) is the third most common gynecologic malignancy worldwide. Most of cases it is of epithelial origin. At the present time there is not a standardized screening method, which makes difficult the early diagnosis. The 5-year survival

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::383a6c9f7f086a8650a13aed84cad9a4
https://pubmed.ncbi.nlm.nih.gov/23650680