Phasor-based hyperspectral snapshot microscopy allows fast imaging of live, three-dimensional tissues for biomedical applications

Autor: Per Niklas Hedde, Rachel Cinco, Leonel Malacrida, Andrés Kamaid, Enrico Gratton

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)

Hedde et al. demonstrate the use of ultrafast phasor-based hyperspectral snapshot microscopy for biomedical imaging. This technique can improve imaging speed by 10-100 fold and enables 3D hyperspectral imaging of live tissues without using expensive

Externí odkaz: https://doaj.org/article/364263388e1947e280262452f6f149c7

Modeling hypercholesterolemia and vascular lipid accumulation in LDL receptor mutant zebrafish

Autor: Chao Liu, Young Sook Kim, Jungsu Kim, Jennifer Pattison, Andrés Kamaid, Yury I. Miller

Publikováno v: Journal of Lipid Research, Vol 59, Iss 2, Pp 391-399 (2018)

Elevated plasma LDL cholesterol is the dominant risk factor for the development of atherosclerosis and cardiovascular disease. Deficiency in the LDL receptor (LDLR) is a major cause of familial hypercholesterolemia in humans, and the LDLR knockout mo

Externí odkaz: https://doaj.org/article/067386c829a04fb0a008dc24af2459f2

A novel nitroalkene-α-tocopherol analogue inhibits inflammation and ameliorates atherosclerosis in Apo E knockout mice

Autor: Jorge Rodriguez-Duarte, Jessica Rossello, Carlos Escande, Francisco J. Schopfer, Leonel Malacrida, Germán Galliussi, Gloria V. López, Carlos Batthyány, Andrés Kamaid, Rosina Dapueto

Publikováno v: British Journal of Pharmacology. 176:757-772

Background and purpose Atherosclerosis is characterized by chronic low-grade inflammation with concomitant lipid accumulation in the arterial wall. Anti-inflammatory and anti-atherogenic properties have been described for a novel class of endogenous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fce8b96addc5b32820da194c8f4faf92
https://doi.org/10.1111/bph.14561

Ultrafast phasor-based hyperspectral snapshot microscopy for biomedical imaging

Autor: Per Niklas Hedde, Enrico Gratton, Andrés Kamaid, Rachel Cinco, Leonel Malacrida

Hyperspectral imaging is highly sought after in many fields including mineralogy and geology, environment and agriculture, astronomy and, importantly, biomedical imaging and biological fluorescence. We developed ultrafast phasor-based hyperspectral s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef9e714b73b416589ea6004b3e49ddb0
https://doi.org/10.1101/2020.10.14.339416

Electrophilic nitroalkene-tocopherol derivatives: synthesis, physicochemical characterization and evaluation of anti-inflammatory signaling responses

Autor: Rosina Dapueto, Andrés Kamaid, Francisco J. Schopfer, Carlos Escande, Germán Galliussi, Gloria V. López, Carlos Batthyány, Lucía Turell, Jorge Rodriguez-Duarte, Gerardo Ferrer-Sueta, Nicholas K.H. Khoo, Bruce A. Freeman

Publikováno v: Scientific Reports
COLIBRI
Universidad de la República
instacron:Universidad de la República
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)

Inflammation plays a major role in the onset and development of chronic non-communicable diseases like obesity, cardiovascular diseases and cancer. Combined, these diseases represent the most common causes of death worldwide, thus development of nove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9f85de849927b84225361cb78a3166
http://europepmc.org/articles/PMC6109136