Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andrés González Barrios"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13946 (2022)
Antifolates such as methotrexate (MTX) have been largely known as anticancer agents because of their role in blocking nucleic acid synthesis and cell proliferation. Their mechanism of action lies in their ability to inhibit enzymes involved in the fo
Externí odkaz:
https://doaj.org/article/f698323a44ac4c5bb809926491584d90
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Fragment-based drug design (FBDD) and pharmacophore modeling have proven to be efficient tools to discover novel drugs. However, these approaches may become limited if the collection of fragments is highly repetitive, poorly diverse, or excessively s
Externí odkaz:
https://doaj.org/article/cfd0e3bc2da9435892cc52a6eb88cbdd
Autor:
David Botero, Jonathan Monk, María Juliana Rodríguez Cubillos, Andrés Rodríguez Cubillos, Mariana Restrepo, Vivian Bernal-Galeano, Alejandro Reyes, Andrés González Barrios, Bernhard Ø. Palsson, Silvia Restrepo, Adriana Bernal
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Xanthomonas phaseoli pv. manihotis (Xpm) is the causal agent of cassava bacterial blight, the most important bacterial disease in this crop. There is a paucity of knowledge about the metabolism of Xanthomonas and its relevance in the pathogenic proce
Externí odkaz:
https://doaj.org/article/25c4c43657e748d99b3d379a4c4859f9
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
The ligand efficiency (LE) indexes have long been used as decision-making criteria in drug discovery and development. However, in the context of fragment-based drug design (FBDD), these metrics often exhibit a strong emphasis toward the selection of
Externí odkaz:
https://doaj.org/article/bab1cd53e1104ddeae27b4fad73ff580
Autor:
Miguel Fernández-Niño, Lina Rojas, Javier Cifuentes, Rodrigo Torres, Andrea Ordoñez, Juan C Cruz, Edgar Francisco Vargas, Diego Pradilla, Oscar Álvarez Solano, Andrés González Barrios
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223670 (2019)
The Escherichia coli's membrane protein OmpA has been identified as a potential biosurfactant due to their amphiphilic nature, and their capacity to stabilize emulsions of dodecane in water. In this study, the influence of surfactant type, concentrat
Externí odkaz:
https://doaj.org/article/4d78f3967b454009a53dfbbb28676834
Publikováno v:
Encuentro Internacional de Educación en Ingeniería.
Producto de la revisión detallada de la formación en ingeniería y el perfil profesional del programa en Ingeniería Química del Departamento de Ingeniería Química y de Alimentos de la Universidad de Los Andes, se adelantó un proceso de reforma
Autor:
Silvia Torres, Valentina Jaramillo, Juan C. Cruz, Carolina Muñoz-Camargo, Andres González Barrios
Publikováno v:
Biology and Life Sciences Forum, Vol 20, Iss 1, p 23 (2022)
Skin burns are injuries of different degrees of complexity (first to third) caused by physical and/or chemical trauma. There is a necessity to improve the rapid retrieval of superficial wounds (first grade) to enhance epithelization, avoiding dehydra
Externí odkaz:
https://doaj.org/article/c70113c9a2794c86ad9748fc0af490d2