Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrés F. Parguiña"'
Autor:
Andrés F, Parguiña, Jana, Alonso, Isaac, Rosa, Paula, Vélez, María J, González-López, Esteban, Guitián, Johannes A, Eble, Johannes A, Ebble, María I, Loza, Ángel, García
Publikováno v:
Blood. 120:e117-e126
C-type lectin-like receptor 2 (CLEC-2) is an essential platelet-activating receptor in hemostasis and thrombosis that is activated by the snake venom rhodocytin. We present here a differential proteomic analysis of basal and rhodocytin-activated plat
Autor:
Diego López-Otero, Elvis Teijeira-Fernández, Isaac Rosa, José Ramón González-Juanatey, Lilian Grigorian-Shamagian, Jana Alonso, Andrés F. Parguiña, Rosa M. Agra, Ángel García
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 31:2957-2964
Objective— Our aim in this study was to provide novel information on the molecular mechanisms playing a major role in the unwanted platelet activation associated with ST-elevation myocardial infarction (STEMI). Methods and Results— We compared th
Autor:
Jana Alonso, Isaac Rosa, Sonia Eiras, Andrés F. Parguiña, José Ramón González-Juanatey, Trinidad Yolanda Rico, Ángel García, Elvis Teijeira-Fernández, Antonio Salgado-Somoza
Publikováno v:
International Journal of Cardiology. 150:283-290
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia found in clinical practice. We combined high-resolution two-dimensional gel electrophoresis (2-DE) and mass spectrometry (MS) to compare the atrial proteome of subjects with AF
Autor:
Isaac Rosa, F. de la Cuesta, Paula Vélez, Ángel García, Sergio Alonso-Orgaz, José Ramón González-Juanatey, Maria G. Barderas, José Moreu, Raymundo Ocaranza-Sánchez, Esteban Guitián, Lilian Grigorian-Shamagian, Andrés F. Parguiña
Publikováno v:
Thrombosis and haemostasis. 112(4)
SummaryMembrane microvesicles (MVs) are released from activated cells, most notably platelets, into the circulation. They represent an important mode of intercellular communication, and their number is increased in patients with acute coronary syndro
Publikováno v:
Journal of proteomics.
Platelets play a fundamental role in hemostasis. Because they do not have a nucleus, proteomics is an ideal way to approach their biochemistry. Platelet proteomics is still a young field that emerged a decade ago. Initial platelet proteomic research
Publikováno v:
Journal of proteomics.
Platelet-derived microparticles (PMP) are elevated in a number of disorders (e.g. cardiovascular disease and cancer). In the present study, we have carried out a high-resolution 2-DE-based proteomic analysis of PMP originated following platelet activ
Autor:
M.G. Barderas, Raymundo Ocaranza-Sánchez, Á. García Méndez, Andrés F. Parguiña, P. Vélez Viéitez, Isaac Rosa, José Ramón González-Juanatey, F. de la Cuesta, Lilian Grigorian-Shamagian, José Moreu, Sergio Alonso-Orgaz
Publikováno v:
Thrombosis Research. 133:S15-S16
Autor:
Jana Alonso, Rosa M. Agra, Andrés F. Parguiña, Isaac Rosa, Lilian Grigorian-Shamagian, José Ramón González-Juanatey, Elvis Teijeira-Fernández, Ángel García
Publikováno v:
Journal of the American College of Cardiology. 55(10)
Autor:
Isaac Rosa, Sonia Severin, Ángel García, Robin Antrobus, Andrés F. Parguiña, Nicole Zitzmann, Steve P. Watson, Yotis A. Senis
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 7(10)
BACKGROUND AND OBJECTIVES: Outside-in integrin alphaIIbbeta3 signaling involves a series of tyrosine kinase reactions that culminate in platelet spreading on fibrinogen. The aim of this study was to identify novel tyrosine phosphorylated signaling pr
Autor:
Maria G. Barderas, R. Gonzalez-Juanatey, R. Ocaranza, Isaac Rosa, L. Grigorian, J. Moreu, Paula Vélez, Ángel García, Andrés F. Parguiña, S. Alonso-Orgaz
Publikováno v:
European Heart Journal. 34:P460-P460
Purpose: Microparticles (MP) are cell-derived membrane vesicles of less than a micron known to be increased in the blood of patients with acute coronary syndromes. They derive from various cells, most notably platelets. Our objective was to compare t