Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andrés F. Marmolejo-Valencia"'
Publikováno v:
SN Applied Sciences, Vol 3, Iss 5, Pp 1-16 (2021)
Abstract G-protein-biased agonism of the mu-opioid receptor (μ-OR) is emerging as a promising strategy in analgesia. A deep understanding of how biased agonists modulate and differentiate G-protein-coupled receptors (GPCR) signaling pathways and how
Externí odkaz:
https://doaj.org/article/6f781fbad40d49acaca8e3e14515a515
Autor:
Fernando Landgrave-Barbosa, Andrés F. Marmolejo-Valencia, Alejandro Baray-Calderón, Hailin Hu, Julio César Aguilar-Cordero, Carlos Amador-Bedolla, Víctor M. Ugalde-Saldivar
Publikováno v:
Journal of Solid State Electrochemistry. 26:649-661
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66954c2ff2d3c50bc56203b914d8cc1e
https://doi.org/10.1007/s10008-021-05078-7
https://doi.org/10.1007/s10008-021-05078-7
Autor:
Adel Nefzi, Fernando Cosme-Vela, R. Bruno Hernández-Alvarado, Andrés F. Marmolejo-Valencia, Karina Martinez-Mayorga, Abraham Madariaga-Mazón
Publikováno v:
Journal of Computer-Aided Molecular Design. 35:1081-1093
Opioids are potent painkillers, however, their therapeutic use requires close medical monitoring to diminish the risk of severe adverse effects. The G-protein biased agonists of the μ-opioid receptor (MOR) have shown safer therapeutic profiles than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d301ee357da5f8bbd6d0a29d41fa3381
https://doi.org/10.1007/s10822-021-00422-5
https://doi.org/10.1007/s10822-021-00422-5
Publikováno v:
SN Applied Sciences, Vol 3, Iss 5, Pp 1-16 (2021)
Abstract G-protein-biased agonism of the mu-opioid receptor (μ-OR) is emerging as a promising strategy in analgesia. A deep understanding of how biased agonists modulate and differentiate G-protein-coupled receptors (GPCR) signaling pathways and how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6eeb051d287269a8fb2539cb81787ea
https://doaj.org/article/6f781fbad40d49acaca8e3e14515a515
https://doaj.org/article/6f781fbad40d49acaca8e3e14515a515
Publikováno v:
Physical chemistry chemical physics : PCCP. 23(31)
The prediction of new organic photovoltaic materials in organic solar cells (OSCs) must include a precise description of charge-transfer states because they are involved in electron-transfer processes such as charge separation and charge recombinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ead0a8016d9e13d89f7afc3a140365
https://pubmed.ncbi.nlm.nih.gov/34323261
https://pubmed.ncbi.nlm.nih.gov/34323261
Autor:
Karina Martinez-Mayorga, Richard A. Houghten, Andrés F. Marmolejo-Valencia, Abraham Madariaga-Mazón, Lawrence Toll, Yangmei Li
Publikováno v:
Drug Discovery Today. 22:1719-1729
Biased activation of G-protein-coupled receptors (GPCRs) is shifting drug discovery efforts and appears promising for the development of safer drugs. The most effective analgesics to treat acute pain are agonists of the μ opioid receptor (μ-OR), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96e4a41d2d1d7440b71d0d378ce950d
https://doi.org/10.1016/j.drudis.2017.07.002
https://doi.org/10.1016/j.drudis.2017.07.002
Allosteric modulation model of the mu opioid receptor by herkinorin, a potent not alkaloidal agonist
Publikováno v:
Journal of Computer-Aided Molecular Design. 31:467-482
Modulation of opioid receptors is the primary choice for pain management and structural information studies have gained new horizons with the recently available X-ray crystal structures. Herkinorin is one of the most remarkable salvinorin A derivativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84bad2d68280489eaf4314328b7ca63
https://doi.org/10.1007/s10822-017-0016-7
https://doi.org/10.1007/s10822-017-0016-7
Publikováno v:
Physical chemistry chemical physics : PCCP. 21(36)
Organic photovoltaic materials (OPVs), with low cost and structure flexibility, are of great interest and importance for their application in solar cell device development. However, the optimization of new OPV structures and the study of the structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3b877ec41605af300dc168eb38d320
https://pubmed.ncbi.nlm.nih.gov/31495832
https://pubmed.ncbi.nlm.nih.gov/31495832
Autor:
Augusto González-Navejas, Karl M. García-Ruiz, Andrés F. Marmolejo-Valencia, Carlos Amador-Bedolla, Laura Dominguez
Publikováno v:
Journal of molecular modeling. 25(5)
Organic photovoltaics (OPV) have been theoretically studied within the usual parameters: open circuit voltage (Voc), short circuit current (Jsc), and fill factor (FF). The first two refer mostly to electronic properties, whereas the last contains all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1958646dd56932d5238e0eca47dcb125
https://pubmed.ncbi.nlm.nih.gov/30945103
https://pubmed.ncbi.nlm.nih.gov/30945103
Autor:
Karina Martinez-Mayorga, Joaquín Barroso-Flores, José L. Medina-Franco, Baldomero Esquivel-Rodriguez, Eric Iván Sánchez-Flores, Andrés F. Marmolejo-Valencia, Juan Carlos García-Ramos, Fernando Cortés-Guzmán
Publikováno v:
Universidad Nacional Autónoma de México
UNAM
Redalyc-UNAM
Journal of the Mexican Chemical Society (México) Num.3 Vol.61
UNAM
Redalyc-UNAM
Journal of the Mexican Chemical Society (México) Num.3 Vol.61
UNIIQUIM database contains molecules from Mexican plants, one of the richest sources of bioactive molecules in the world. Here, we describe the chemical and toxicological profile of molecules with analgesic activity from UNIIQUIM. Most of the compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e89f9b707ee72e2713fa2f0f02cdb29
https://www.redalyc.org/articulo.oa?id=47553303003
https://www.redalyc.org/articulo.oa?id=47553303003
