Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

Autor: Pcawg Drivers, Chris Sander, Todd A. Johnson, Jüri Reimand, Lina Wadi, Dimple Chakravarty, Claes Wadelius, Rory Johnson, Abel Gonzalez-Perez, Jing Zhang, Nicholas A Sinnott-Armstrong, Icgc, Abdullah Kahraman, Nicholas J. Haradhvala, Husen M. Umer, Priyanka Dhingra, Michael S. Lawrence, Inigo Martincorena, Ben Raphael, André Kahles, Chen Hong, Esther Rheinbay, Joana Carlevaro-Fita, Loris Mularoni, Tatsuhiko Tsunoda, Qianyun Guo, Andrés Arturo Lanzós Camaioni, Yosef E. Maruvka, Josh Stuart, Dong-Hoon Lee, Jakob Skou Pedersen, Jaegil Kim, Klev Diamanti, Nuno A. Fonseca, Julian M. Hess, Federico Abascal, Samir B. Amin, Kjong-Van Lehmann, Carl Herrmann, Ekta Khurana, Mark Gerstein, Mark A. Rubin, Mark P. Hamilton, Lars Feuerbach, Oriol Pich, Lincoln Stein, Keunchil Park, Keith A. Boroevich, Liis Uusküla-Reimand, Ciyue Shen, Lucas Lochovsky, David Tamborero, Gad Getz, Shimin Shuai, Randi Istrup Istrup Pedersen, Johanna Bertl, Lina Sieverling, Young-Wook Kim, Morten Muhlig Nielsen, Keren Isaev, Calvin Wing Yiu Chan, Asger Hobolth, Malene Juul, Eric Minwei Liu, Henrik Hornshøj, Jan Komorowski, Sushant Kumar, Nuria Lopez-Bigas, David A. Wheeler, Manolis Kellis, Peter J. Campbell, Radhakrishnan Sabarinathan, Grace Tiao, Gordon Saksena, Henrik Tobias Madsen

Publikováno v: bioRxiv
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Discovery of cancer drivers has traditionally focused on the identification of protein-coding genes. Here we present a comprehensive analysis of putative cancer driver mutations in both protein-coding and non-coding genomic regions across >2,500 whol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaec91ebd7eaa8c5486f9e530572e585
https://doi.org/10.1101/237313