Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Andrée R. Olivier"'
Autor:
George Thomas, Andrée R. Olivier
Publikováno v:
Growth Regulation and Carcinogenesis ISBN: 9781351072311
Growth Regulation and Carcinogenesis
Growth Regulation and Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8580e1cdf6446c2be64083ef6edae99
https://doi.org/10.1201/9781351072311-18
https://doi.org/10.1201/9781351072311-18
Autor:
George Thomas, Andrée R. Olivier
Publikováno v:
Growth Regulation and Carcinogenesis ISBN: 9781351072311
Growth Regulation and Carcinogenesis
Growth Regulation and Carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1dfbdfe41f720e273d027b5a85d8241
https://doi.org/10.1201/9781351072311-17
https://doi.org/10.1201/9781351072311-17
Autor:
Paul Gillespie, Yimin Qian, Tsutomu Sato, Kuo-Sen Huang, Xiaolei Zhang, Weiya Yun, Andrée R. Olivier, Karin Conde-Knape, Stuart Hayden, Qing Xiang, David Robert Bolin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:2936-2940
Glycogen synthase (GS) catalyzes the transfer of glucose residues from UDP-glucose to a glycogen polymer chain, a critical step for glucose storage. Patients with type 2 diabetes normally exhibit low glycogen levels and decreased muscle glucose uptak
Autor:
Kuo-Sen Huang, Joseph A. Sergi, Stuart Hayden, Yonglin Ren, Weiya Yun, Qing Xiang, Mei Liu, Andrée R. Olivier, Yimin Qian, Karin Conde-Knape, Lin Yi, Xiaolei Zhang, David Robert Bolin, Paul Gillespie
Publikováno v:
MedChemComm. 4:833-838
Decreased glycogen synthesis and turnover is a common defect in type 2 diabetic patients. Activating glycogen synthase, the enzyme that catalyses the transfer of glucose from UDP-glucose to a glycogen polymer chain, could be a potential therapeutic t
Autor:
Kshitij Chhabilbhai Thakkar, Bruce L. Banner, Shiming Li, Nicholas Marcopulos, Joseph A. Sergi, Jolly Bose, Weiya Yun, Catherine Zwingelstein, Adrian Wai-Hing Cheung, Kyungjin Kim, Steven Joseph Berthel, Bingbing Wang, Lucja Orzechowski, Andrée R. Olivier
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:7518-7522
High throughput screening of the Roche compound collection led to the identification of diaminopyrroloquinazoline series as a novel class of PTP1B inhibitors. Structural modification of diaminopyrroloquinazoline series resulted in pyrido[2,3-d]pyrimi
Autor:
Marcia Renzetti, Jones Philip Stephen, Ralph Garippa, Glyn Williams, Joseph A. Sergi, Ying Peng, Kevin Richard Guertin, Fiorenza Falcioni, Hilary A. Overton, Lida Qi, Rogely Boyce, Andrée R. Olivier, Karen Wang, Rachel M. Dunsdon, Mathew Taylor, Brian William Dymock, Lina Setti
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:2895-2898
A novel series of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents have been identified. These compounds show non-selective inhibitory properties against a panel of protein tyrosine phosphatases including PTP1B. Comp
Publikováno v:
Biochemical Journal. 318:519-525
Bombesin induces the down-regulation of protein kinase C-delta (PKC-delta) and PKC-epsilon in Swiss 3T3 cells. Simultaneous addition of transforming growth factor beta 1 (TGF beta 1) selectively blocks PKC-delta down-regulation at mid-S-phase, wherea
Autor:
Peter J. Parker, Andrée R. Olivier
Publikováno v:
Journal of Biological Chemistry. 269:2758-2763
Swiss 3T3 cells contain protein kinase C (PKC) isotypes alpha, delta, epsilon and zeta (Olivier, A. R., and Parker, P. J. (1992) J. Cell. Physiol. 152, 240-244). Acute stimulation of quiescent cells with the neuropeptide bombesin decreases the mobili
Autor:
Susan C. Kiley, Andrée R. Olivier, Catherine J. Pears, Peter J. Parker, Dick Schaap, Susan Jaken
Publikováno v:
Biochemical Society Transactions. 20:603-607
Publikováno v:
FEBS Letters. 288:5-9
Phorbol esters, tetradecanoylphorbolacetate, sapintoxin-A, 12-deoxyphorbol-phenylacetate, 12-deoxyphorbol-phenylacetate-20-acetate, thymeleatoxin and resiniferatoxin were investigated for their abilities to activate the PKC-isotypes α, β1, γ, δ a