Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Andréa Rodrigues Ávila"'
Autor:
Bárbara Adriana Ferreira dos Santos Trigueiros MSc, Ivan José Santana Santos PhD, Fabricia Pires Pimenta PhD, Andréa Rodrigues Ávila PhD
Publikováno v:
Cancer Control, Vol 31 (2024)
Background Alterations in PI3K function are directly related to cancer, making PI3K inhibitors suitable options for anticancer therapies. Information on therapy using different types of PI3K inhibitors is available in literature, providing indication
Externí odkaz:
https://doaj.org/article/2301a5e414714258b31080ab0fea5647
Autor:
Denis Amilton dos Santos, Higo Fernando Santos Souza, Ariel M. Silber, Tatiana de Arruda Campos Brasil de Souza, Andréa Rodrigues Ávila
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
The apicomplexan parasite Toxoplasma gondii is the causative agent of toxoplasmosis, a global disease that significantly impacts human health. The clinical manifestations are mainly observed in immunocompromised patients, including ocular damage and
Externí odkaz:
https://doaj.org/article/1704539244e44e578a87b8fefa200e5d
Autor:
Bárbara Adriana Ferreira dos Santos TRIGUEIROS, Andréa Rodrigues ÁVILA, Fabricia Pires PIMENTA
Publikováno v:
Transinformação, Vol 34 (2022)
Abstract: As part of the innovation process, clinical research generates valuable data to assess technological solutions in healthcare, linking scientific research and knowledge transfer to provide beneficial innovations for society. However, the gen
Externí odkaz:
https://doaj.org/article/1c9e92447ad3438b80700a9d0ef3df3e
Autor:
Mariana Sayuri Ishikawa Fragoso, Caroline Moraes de Siqueira, Francisca Nathália Luna Vitorino, Alexandre Zanatta Vieira, Érica Santos Martins-Duarte, Helisson Faoro, Júlia Pinheiro Chagas da Cunha, Andréa Rodrigues Ávila, Sheila Cristina Nardelli
Publikováno v:
Microorganisms, Vol 11, Iss 6, p 1558 (2023)
Toxoplasma gondii is an obligate intracellular parasite of the phylum Apicomplexa and causes toxoplasmosis infections, a disease that affects a quarter of the world’s population and has no effective cure. Epigenetic regulation is one of the mechani
Externí odkaz:
https://doaj.org/article/3c05b599fde24311820e98a1aec00732
Publikováno v:
Pathogens, Vol 12, Iss 1, p 32 (2022)
Chagas disease is a neglected tropical disease caused by Trypanosoma cruzi. This protozoan developed several mechanisms to infect, propagate, and survive in different hosts. The specific expression of proteins is responsible for morphological and met
Externí odkaz:
https://doaj.org/article/3e4366cbc79c4f6fbda517940f2cada4
Autor:
Mariana Galvão Ferrarini, Lindice Mitie Nisimura, Richard Marcel Bruno Moreira Girard, Mayke Bezerra Alencar, Mariana Sayuri Ishikawa Fragoso, Carlla Assis Araújo-Silva, Alan de Almeida Veiga, Ana Paula Ressetti Abud, Sheila Cristina Nardelli, Rossiane C. Vommaro, Ariel Mariano Silber, Marie France-Sagot, Andréa Rodrigues Ávila
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Currently, the drugs used for toxoplasmosis have severe toxicity to human cells, and the treatment still lacks effective and safer alternatives. The search for novel drug targets is timely.
Externí odkaz:
https://doaj.org/article/ab8bd52f627c4de5b2e487eb81926d12
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Control of gene expression is crucial for parasite survival and is the result of a series of processes that are regulated to permit fine-tuning of gene expression in response to biological changes during the life-cycle of apicomplexan parasi
Externí odkaz:
https://doaj.org/article/7e4f1d28634e48e3b39f6c9972e19a20
Autor:
Jimena Ferreira da Costa, Mariana Galvão Ferrarini, Sheila Cristina Nardelli, Samuel Goldenberg, Andréa Rodrigues Ávila, Fabíola Barbieri Holetz
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 113, Iss 6 (2018)
BACKGROUND Eukaryotic ribonucleoprotein (RNP) granules are important for the regulation of RNA fate. RNP granules exist in trypanosomatids; however, their roles in controlling gene expression are still not understood. XRNA is a component of granules
Externí odkaz:
https://doaj.org/article/7011ebba78fc4a969aa4218ed700acad
Autor:
Rafael Luis Kessler, Daniela Fiori Gradia, Rita de Cássia Pontello Rampazzo, Édio Elígio Lourenço, Nilson José Fidêncio, Lauro Manhaes, Christian Macagnan Probst, Andréa Rodrigues Ávila, Stenio Perdigão Fragoso
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67441 (2013)
Trypanosoma cruzi is the etiological agent of Chagas disease, an illness that affects about 10 million people, mostly in South America, for which there is no effective treatment or vaccine. In this context, transgenic parasites expressing reporter ge
Externí odkaz:
https://doaj.org/article/cb46d9c4c69d4cda9d3683e57d4b3cdc
Autor:
Nardelli, Mariana Sayuri Ishikawa Fragoso, Caroline Moraes de Siqueira, Francisca Nathália Luna Vitorino, Alexandre Zanatta Vieira, Érica Santos Martins-Duarte, Helisson Faoro, Júlia Pinheiro Chagas da Cunha, Andréa Rodrigues Ávila, Sheila Cristina
Publikováno v:
Microorganisms; Volume 11; Issue 6; Pages: 1558
Toxoplasma gondii is an obligate intracellular parasite of the phylum Apicomplexa and causes toxoplasmosis infections, a disease that affects a quarter of the world’s population and has no effective cure. Epigenetic regulation is one of the mechani