Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Andréa Mara Macedo"'
Autor:
Mariana Boroni, Michael Sammeth, Sandra Grossi Gava, Natasha Andressa Nogueira Jorge, Andréa Mara Macedo, Carlos Renato Machado, Marina Moraes Mourão, Glória Regina Franco
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Spliced leader dependent trans-splicing (SLTS) has been described as an important RNA regulatory process that occurs in different organisms, including the trematode Schistosoma mansoni. We identified more than seven thousand putative SLTS si
Externí odkaz:
https://doaj.org/article/0e756365d71143b4b464e9bcddd7f1ab
Autor:
Carolina Furtado Torres-Silva, Bruno Marçal Repolês, Hugo Oliveira Ornelas, Andréa Mara Macedo, Glória Regina Franco, Sérgio Danilo Junho Pena, Erich Birelli Tahara, Carlos Renato Machado
Publikováno v:
Genetics and Molecular Biology, Iss 0 (2018)
Abstract Trypanosoma cruzi is the etiological agent of Chagas disease, a public health challenge due to its morbidity and mortality rates, which affects around 6-7 million people worldwide. Symptoms, response to chemotherapy, and the course of Chagas
Externí odkaz:
https://doaj.org/article/f5108e6763e5450babc66021911a2ad1
Autor:
Marcela Segatto, Lucas Secchim Ribeiro, Dorcas Lamounier Costa, Carlos Henrique Nery Costa, Márcia Rosa de Oliveira, Sílvio Fernando Guimarães Carvalho, Andréa Mara Macedo, Helder Magno Silva Valadares, Reynaldo Dietze, Cristiana Ferreira Alves de Brito, Elenice Moreira Lemos
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 107, Iss 1, Pp 39-47 (2012)
Leishmania infantum (syn. Leishmania chagasi) is the etiological agent of visceral leishmaniasis (VL) in Brazil. The epidemiology of VL is poorly understood. Therefore, a more detailed molecular characterization at an intraspecific level is certainly
Externí odkaz:
https://doaj.org/article/9d1faab131c145d7ad9611c264606428
Autor:
Sonia Gumes Andrade, Rozália Figueira Campos, Mario Steindel, Marcos Lázaro Guerreiro, Juracy Barbosa Magalhães, Marcio Cerqueira de Almeida, Joice Neves Reis, Viviane Corrêa Santos, Helder Magno Silva Valadares, Mitermayer Galvão dos Reis, Andréa Mara Macedo
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 106, Iss 8, Pp 948-956 (2011)
We examined strains of Trypanosoma cruzi isolated from patients with acute Chagas disease that had been acquired by oral transmission in the state of Santa Catarina, Brazil (2005) and two isolates that had been obtained from a marsupial (Didelphis au
Externí odkaz:
https://doaj.org/article/7a48975e4e21457788e5cebef77ea914
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 104, Pp 108-114 (2009)
Although the genome of Trypanosoma cruzi has been completely sequenced, little is known about its population structure and evolution. Since 1999, two major evolutionary lineages presenting distinct epidemiological characteristics have been recognised
Externí odkaz:
https://doaj.org/article/d8f73085448c4628a1391b18e63ee331
Autor:
Silvia Regina Costa Dias, Mariana eBoroni, Elizângela Almeida Rocha, Thomaz eLüscher-Dias, Daniela eLaet-Souza, Fabricio Marcus Silva Oliveira, Mainá eBitar, Andréa Mara Macedo, Carlos Renato Machado, Marcelo Vidigal Caliari, Gloria Regina Franco
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Schistosomiasis is a neglected tropical disease, and after malaria, is the second most important tropical disease in public health. A vaccine that reduces parasitemia is desirable to achieve mass treatment with a low cost. Although potential antigens
Externí odkaz:
https://doaj.org/article/ee29853b147d4e919628cd8b3d0e341c
Autor:
Mainá eBitar, Mariana eBoroni, Andréa Mara Macedo, Carlos Renato eMachado, Glória Regina Franco
Publikováno v:
Frontiers in Genetics, Vol 4 (2013)
The spliced leader (SL) is a gene that generates a functional ncRNA that is composed of two regions: an intronic region of unknown function (SLi) and an exonic region (SLe), which is transferred to the 5’ end of independent transcripts yielding mat
Externí odkaz:
https://doaj.org/article/c9d7d4e696954a9386319ac16a56db13
Autor:
Fabio Mitsuo Lima, Renata Torres Souza, Fábio Rinaldo Santori, Michele Fernandes Santos, Danielle Rodrigues Cortez, Roberto Moraes Barros, Maria Isabel Cano, Helder Magno Silva Valadares, Andréa Mara Macedo, Renato Arruda Mortara, José Franco da Silveira
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63738 (2013)
Trypanosoma cruzi comprises a pool of populations which are genetically diverse in terms of DNA content, growth and infectivity. Inter- and intra-strain karyotype heterogeneities have been reported, suggesting that chromosomal rearrangements occurred
Externí odkaz:
https://doaj.org/article/dec6108685254a1b90f7a5d09957b870
Autor:
Helder Magno Silva Valadares, Juliana Ramos Pimenta, Marcela Segatto, Vanja Maria Veloso, Mônica Lúcia Gomes, Egler Chiari, Kenneth John Gollob, Maria Terezinha Bahia, Marta de Lana, Glória Regina Franco, Carlos Renato Machado, Sérgio Danilo Junho Pena, Andréa Mara Macedo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 7, p e1722 (2012)
Trypanosoma cruzi, the etiological agent of Chagas disease, is a polymorphic species. Evidence suggests that the majority of the T. cruzi populations isolated from afflicted humans, reservoir animals, or vectors are multiclonal. However, the extent a
Externí odkaz:
https://doaj.org/article/789058e0d4f341bd824d5e232f02ac65
Autor:
Claudiney Melquíades Rodrigues, Helder Magno Silva Valadares, Amanda Fortes Francisco, Jerusa Marilda Arantes, Camila França Campos, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Márcio Sobreira Silva Araujo, Rosa Maria Esteves Arantes, Egler Chiari, Glória Regina Franco, Carlos Renato Machado, Sérgio Danilo Junho Pena, Ana Maria Caetano Faria, Andréa Mara Macedo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 10, p e846 (2010)
A century after the discovery of Trypanosoma cruzi in a child living in Lassance, Minas Gerais, Brazil in 1909, many uncertainties remain with respect to factors determining the pathogenesis of Chagas disease (CD). Herein, we simultaneously investiga
Externí odkaz:
https://doaj.org/article/95e6da8deeb44cf396088e97fac347c4