Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Andréa L, Sertié"'
Autor:
Danyllo Oliveira, Livia Luz, Felipe de Souza Leite, Carolini Kaid, Oswaldo Keith Okamoto, Mayana Zatz, Uirá Souto Melo, Thalita Figueiredo, Luiz Carlos de Caires, Andréa L. Sertié, Sergio Verjovski-Almeida, Ernesto Goulart, Murilo S. Amaral, David A. Morales-Vicente, Miguel Mitne-Neto, Claudia D. C. Navarro, Joyce Esposito, Luciana M Alves
Publikováno v:
Human Molecular Genetics. 29:1465-1475
Amyotrophic lateral sclerosis type 8 (ALS8) is an autosomal dominant form of ALS, which is caused by pathogenic variants in the VAPB gene. Here we investigated five ALS8 patients, classified as ‘severe’ and ‘mild’ from a gigantic Brazilian ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f507f86e85a31ca63d6eca9bd4a055
https://doi.org/10.1093/hmg/ddaa069
https://doi.org/10.1093/hmg/ddaa069
Autor:
Daniel Martins-de-Souza, Silvia S. Costa, Gavin J. Sutton, Eduardo M. Reis, Suzana A. M. Ezquina, Elaine Cristina Zachi, O. J. Sosa, Andréa L. Sertié, Angela May Suzuki, A. Y. Alves, Andressa Gois Morales, Irina Voineagu, Gabriela Seabra, D. Y. Sunaga-Franze, Mariana Soares Fogo, L. Sardinha, Maria Rita Passos-Bueno, Karina Griesi-Oliveira, B. G. G. Pinto, Carla Rosenberg, A. P. Bueno
Publikováno v:
Molecular Psychiatry
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Evaluation of expression profile in autism spectrum disorder (ASD) patients is an important approach to understand possible similar functional consequences that may underlie disease pathophysiology regardless of its genetic heterogeneity. Induced plu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c76f56dd3318128058c6d239c26288
http://europepmc.org/articles/PMC8159745
http://europepmc.org/articles/PMC8159745
Autor:
Flavia I.V. Errera, Luís H. Canani, Erika Yeh, Érika Kague, Lucia M. Armelin-Corrêa, Oscar T. Suzuki, Balduíno Tschiedel, Maria Elizabeth R. Silva, Andréa L. Sertié, Maria Rita Passos-Bueno
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 80, Iss 1, Pp 167-177 (2008)
Collagen XVIII can generate two fragments, NC11-728 containing a frizzled motif which possibly acts in Wnt signaling and Endostatin, which is cleaved from the NC1 and is a potent inhibitor of angiogenesis. Collagen XVIII and Wnt signaling have recent
Externí odkaz:
https://doaj.org/article/87cbf7807df54e23ad4791e815f34359
Autor:
Maria Rita Passos-Bueno, Oscar T. Suzuki, Lucia M. Armelin-Correa, Andréa L. Sertié, Flavia I.V. Errera, Kelly Bagatini, Fernando Kok, Katia R.M. Leite
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 78, Iss 1, Pp 123-131 (2006)
Collagen XVIII, a proteoglycan, is a component of basement membranes (BMs). There are three distinct isoforms that differ only by their N-terminal, but with a specific pattern of tissue and developmental expression. Cleavage of its C-terminal produce
Externí odkaz:
https://doaj.org/article/bf7be90ae43e464181b6dfed8d15f879
Autor:
Andréa L. Sertié, Janaina Sena de Souza, Fernanda Mansur, Maria Rita Passos-Bueno, Karina Griesi-Oliveira, André Luiz Teles e Silva, Ana Karolyne Santos Gomes, Juliana Magdalon
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7579, p 7579 (2021)
International Journal of Molecular Sciences
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Volume 22
Issue 14
International Journal of Molecular Sciences
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Volume 22
Issue 14
In recent years, accumulating evidence has shown that the innate immune complement system is involved in several aspects of normal brain development and in neurodevelopmental disorders, including autism spectrum disorder (ASD). Although abnormal expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5eb9efc671f0686c7f1931eb6ebc269
https://www.mdpi.com/1422-0067/22/14/7579
https://www.mdpi.com/1422-0067/22/14/7579
Autor:
Gabriela Ferraz Leal, João Ricardo Mendes de Oliveira, Ernesto Goulart, Danyllo Oliveira, Mayana Zatz, Ana Cristina Victorino Krepischi, Andréa L. Sertié, Camila Manso Musso, Luiz Carlos de Caires, Angela Maria Vianna-Morgante
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
BackgroundHereditary primary microcephaly (MCPH) is mainly characterised by decreased occipitofrontal circumference and variable degree of intellectual disability. MCPH with a dominant pattern of inheritance is a rare condition, so far causally linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37962bd2b4533387dd18400da09ee601
https://doi.org/10.1136/jmedgenet-2018-105471
https://doi.org/10.1136/jmedgenet-2018-105471
Autor:
Juliana Magdalon, Karina Griesi-Oliveira, Andréa L. Sertié, Guilherme L. Yamamoto, Sandra M Sánchez-Sánchez, Maria Rita Passos-Bueno, Carolina Santacruz-Perez, Mariana Soares Fogo
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The Reelin-DAB1 signaling pathway plays a crucial role in regulating neuronal migration and synapse function. Although many rare heterozygous variants in the Reelin gene (RELN) have been identified in patients with autism spectrum disorder (ASD), mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bd233a185ca706b7266b57089371f1
https://doi.org/10.1002/humu.23584
https://doi.org/10.1002/humu.23584
Autor:
Lucas Assis Pereira, Karina Griesi-Oliveira, Karina Tozatto-Maio, Barbara Ferri Moraschi, Andréa L. Sertié, Luiz Vicente Rizzo, Ricardo Weinlich, Davi Coe Coe Torres, Mariana Tereza Lira Benício, Priscila Keiko Matsumoto Martin, Mariana Morato Marques
Publikováno v:
Blood. 138:1857-1857
Background: Although gene editing by CRISPR/Cas9 is a promising curative strategy for inherited and acquired diseases, potential off-targets remain a major concern. Most computational and biochemical methods for off-target search have focused on sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::125ab423425c12a1d4e09f57a7bbaa30
https://doi.org/10.1182/blood-2021-153088
https://doi.org/10.1182/blood-2021-153088
Autor:
Mario Ferretti, Eliane Antonioli, Natalia Torres, Carla de Azevedo Piccinato, Andréa L. Sertié
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0204784 (2019)
PLoS ONE, Vol 14, Iss 1, p e0204784 (2019)
Background aimsDelaying replicative senescence and extending lifespan of human mesenchymal stromal cells (MSCs) may enhance their potential for tissue engineering and cell based therapies. Accumulating evidence suggests that inhibitors of the mTOR si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c71ba7c1e68491c5e6a2d96470fd057
Autor:
Danyllo, Oliveira, Gabriela Ferraz, Leal, Andréa L, Sertié, Luiz Carlos, Caires, Ernesto, Goulart, Camila Manso, Musso, João Ricardo Mendes de, Oliveira, Ana Cristina Victorino, Krepischi, Angela Maria, Vianna-Morgante, Mayana, Zatz
Publikováno v:
Journal of medical genetics. 56(8)
Hereditary primary microcephaly (MCPH) is mainly characterised by decreased occipitofrontal circumference and variable degree of intellectual disability. MCPH with a dominant pattern of inheritance is a rare condition, so far causally linked to patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5fa905a20087722e15890bb4200ac3d
https://pubmed.ncbi.nlm.nih.gov/30301738
https://pubmed.ncbi.nlm.nih.gov/30301738