Zobrazeno 1 - 8
of 8
pro vyhledávání: '"André Winkler"'
Autor:
Yannic C. Bartsch, Johann Rahmöller, Maria M. M. Mertes, Susanne Eiglmeier, Felix K. M. Lorenz, Alexander D. Stoehr, Dominique Braumann, Alexandra K. Lorenz, André Winkler, Gina-Maria Lilienthal, Janina Petry, Juliane Hobusch, Moritz Steinhaus, Constanze Hess, Vivien Holecska, Carolin T. Schoen, Carolin M. Oefner, Alexei Leliavski, Véronique Blanchard, Marc Ehlers
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Pro- and anti-inflammatory effector functions of IgG antibodies (Abs) depend on their subclass and Fc glycosylation pattern. Accumulation of non-galactosylated (agalactosylated; G0) IgG Abs in the serum of rheumatoid arthritis and systemic lupus eryt
Externí odkaz:
https://doaj.org/article/8ade56cdc6304236a4c695e38161b7a8
Publikováno v:
F1000Research, Vol 2 (2013)
Red blood cells (RBCs) from a rhesus D (RhD)-positive fetus that reach the bloodstream of an RhD-negative pregnant woman during birth can induce a pathogenic antibody (Ab) response against the RhD-positive RBCs, leading to fetal hemolytic disease in
Externí odkaz:
https://doaj.org/article/62fa9e8e0acb44a4a15cf019e7ca6f95
Autor:
Janina Petry, Ari Waisman, Hidehiro Fukuyama, Manfred Wuhrer, Moritz Steinhaus, Raghu Erapaneedi, Simon Eschweiler, Gabriela Salinas, Ryota Sato, Friederike Berberich-Siebelt, Noortje de Haan, Lilian Aly, Hanna B. Lunding, Rudolf A. Manz, Marc Ehlers, Samuel Huber, Hauke Busch, Dominique Braumann, Timo Gemoll, Thomas Korn, Christoph Hölscher, Véronique Blanchard, André Winkler, Stefan Rose-John, Sander Wagt, Anastasios D. Giannou, Kyra Kuhnigk, Johann Rahmöller, Jens K. Habermann, Alexei Leliavski, Mattias Collin, Björn Rabe, Louise A. de Neef, Vanessa Krémer, Alexandra Hölscher, Yannic C. Bartsch, Gina-Maria Lilienthal, Juliane Hobusch, Nir Yogev
Publikováno v:
Journal of Allergy and Clinical Immunology, 146(3), 652-666.e11. MOSBY-ELSEVIER
Background: Effector functions of IgG Abs are regulated by their Fc N-glycosylation pattern. IgG Fc glycans that lack galactose and terminal sialic acid residues correlate with the severity of inflammatory (auto)immune disorders and have also been li
Autor:
Susanne Eiglmeier, André Winkler, Alexandra Lorenz, Alexander D. Stoehr, Constanze Hess, Marc Ehlers, Vivien Holecska, Anna-Lena Schoen, Carolin T. Schoen, Tim Schommartz, Hedda Wardemann, Maria M.M. Mertes
Publikováno v:
The Journal of Immunology. 187:2953-2965
The role of TLR9 in the development of the autoimmune disease systemic lupus erythematosus is controversial. In different mouse models of the disease, loss of TLR9 abolishes the generation of anti-nucleosome IgG autoantibodies but at the same time ex
Autor:
Anna Lena Schoen, Benjamin Tiburzy, Dominique Petzold, André Winkler, Hedda Wardemann, Marc Ehlers, Michael P. Madaio, Markus Berger, Carolin T. Schoen, Tim Schommartz, Alexander D. Stoehr, Jörg Köhl, Susanne Eiglmeier, Véronique Blanchard, Anne Herrmann, Maria M.M. Mertes, Rudolf A. Manz, Josephine Bitterling, Vivien Holecska, Alexandra Lorenz, Constanze Hess
Antigen-specific Abs are able to enhance or suppress immune responses depending on the receptors that they bind on immune cells. Recent studies have shown that pro- or antiinflammatory effector functions of IgG Abs are also regulated through their Fc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d13c271ff94e63792d07e4220817e79
https://europepmc.org/articles/PMC3754242/
https://europepmc.org/articles/PMC3754242/
Publikováno v:
F1000Research
Red blood cells (RBCs) from a rhesus D (RhD)-positive fetus that reach the bloodstream of an RhD-negative pregnant woman during birth can induce a pathogenic antibody (Ab) response against the RhD-positive RBCs, leading to fetal hemolytic disease in
Autor:
André Winkler, Ralf Ludwig, Regina Kilchenstein, Falk Nimmerjahn, Jörg Köhl, Detlef Zillikens, Jacqueline U. McDonald, Nathaniel L. Harris, Eva Wex, Marc Ehlers, Constanze Hess, Marcela Rosas, Dominique Petzold, Markus Berger, Gordon D. Brown, Philip R. Taylor, Selinda J. Orr, Irina Majoul, Manoj K. Pandey, Richard Strait, Fred D. Finkelman, Julia Figge, Christian M. Karsten, Gabriele Köhl, Delyth M. Reid, Véronique Blanchard
Publikováno v:
Nature medicine. 18(9)
Complement is an ancient danger sensing system playing critical roles in host defense, immune surveillance and homeostasis1. C5a and its G-Protein-coupled receptor mediate many of the pro-inflammatory properties of complement2. Despite its critical r
Autor:
Eckard Hamelmann, Peter König, Vivien Holecska, Mattias Collin, Carolin M. Oefner, Jörg Köhl, Josephine Bitterling, Christoph Loddenkemper, Alexandra Lorenz, Marc Ehlers, Dominique Petzold, Max Löhning, Maria M.M. Mertes, Dana Vu Van, Melanie Huxdorf, Heike A. Ströver, Andreas Hutloff, Tim Schommartz, Yves Laumonnier, Constanze Hess, Hedda Wardemann, Anna Lena Schoen, Carolin T. Schoen, Markus Berger, Susanne Eiglmeier, Véronique Blanchard, Elke O. Luger, Inken Schmudde, Alexander D. Stoehr, Yasemin Darcan-Nikolaisen, André Winkler, Arnd Petersen, Ahmed N. Hegazy
Publikováno v:
Journal of Allergy and Clinical Immunology. 129:1647-1655.e13
Background Under inflammatory conditions, T cell–dependent (TD) protein antigens induce proinflammatory T- and B-cell responses. In contrast, tolerance induction by TD antigens without costimulation triggers the development of regulatory T cells. U