Zobrazeno 1 - 10
of 26
pro vyhledávání: '"André Voelzmann"'
Autor:
Ryan J. H. West, Joanne L. Sharpe, André Voelzmann, Anna L. Munro, Ines Hahn, Richard A. Baines, Stuart Pickering-Brown
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract A large intronic hexanucleotide repeat expansion (GGGGCC) within the C9orf72 (C9orf72-SMCR8 Complex Subunit) locus is the most prevalent genetic cause of both Frontotemporal Dementia (FTD) and Motor Neuron Disease (MND). In patients this exp
Externí odkaz:
https://doaj.org/article/4e9a52c5a5ea4a479ca7cd7829ad0e49
Publikováno v:
Neural Development, Vol 14, Iss 1, Pp 1-28 (2019)
Abstract Axons are the slender, cable-like, up to meter-long projections of neurons that electrically wire our brains and bodies. In spite of their challenging morphology, they usually need to be maintained for an organism's lifetime. This makes them
Externí odkaz:
https://doaj.org/article/cc49e45a31e041a78115bd47689071b9
Autor:
Mariangela Sociale, Anna-Lena Wulf, Bernadette Breiden, Kathrin Klee, Melanie Thielisch, Franka Eckardt, Julia Sellin, Margret H. Bülow, Sinah Löbbert, Nadine Weinstock, André Voelzmann, Joachim Schultze, Konrad Sandhoff, Reinhard Bauer
Publikováno v:
Cell Reports, Vol 22, Iss 4, Pp 967-978 (2018)
Maintenance of metabolic homeostasis requires adaption of gene regulation to the cellular energy state via transcriptional regulators. Here, we identify a role of ceramide synthase (CerS) Schlank, a multiple transmembrane protein containing a catalyt
Externí odkaz:
https://doaj.org/article/6d12fa84536348079733876a5644e65b
Autor:
Yue Qu, Ines Hahn, Meredith Lees, Jill Parkin, André Voelzmann, Karel Dorey, Alex Rathbone, Claire T Friel, Victoria J Allan, Pilar Okenve-Ramos, Natalia Sanchez-Soriano, Andreas Prokop
Publikováno v:
eLife, Vol 8 (2019)
Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They play important roles in neurons, as suggested by inhibition of axon growth and regeneration through the ARF activator Efa6 in C. elegans, and by neurodevelopmenta
Externí odkaz:
https://doaj.org/article/4f7597d325c748c2846b745dd23b04fa
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619896
The use of primary neuronal cultures generated from Drosophila tissue provides a powerful model for studies of transport mechanisms. Cultured fly neurons provide similarly detailed subcellular resolution and applicability of pharmacology or fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94a15c9c5c753ff49a23f4f1c7389284
https://doi.org/10.1007/978-1-0716-1990-2_23
https://doi.org/10.1007/978-1-0716-1990-2_23
Autor:
Yu-Ting Liew, André Voelzmann, Liliana M. Pinho-Correia, Thomas Murphy, Haydn Tortoishell, Jill Parkin, David M.D. Bailey, Matthias Landgraf, Andreas Prokop
Axons are the slender, up to meter-long projections of neurons that form the biological cables wiring our bodies. Most of these delicate structures must survive for an organism’s lifetime, meaning up to a century in humans. Axon maintenance require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218ee3545aeb6aea4b857abbe8e0e257
https://doi.org/10.1101/2021.12.23.473961
https://doi.org/10.1101/2021.12.23.473961
Autor:
Judith B Fuelle, André Voelzmann, Laura Anne Lowery, Ines Hahn, Andreas Prokop, Natalia Sanchez-Soriano, Paula G. Slater, Jill Parkin
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009647 (2021)
Hahn, I, Voelzmann, A, Parkin, J, Fülle, J B, Slater, P G, Lowery, L A, Sanchez-Soriano, N & Prokop, A 2021, ' Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons ', PLoS Genetics, vol. 17, no. 7, 1009647 . https://doi.org/10.1371/journal.pgen.1009647
PLoS Genetics
PLOS GENETICS
Hahn, I, Voelzmann, A, Parkin, J, Fülle, J B, Slater, P G, Lowery, L A, Sanchez-Soriano, N & Prokop, A 2021, ' Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons ', PLoS Genetics, vol. 17, no. 7, 1009647 . https://doi.org/10.1371/journal.pgen.1009647
PLoS Genetics
PLOS GENETICS
The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation is regulated in cells. Focussing on the essential microtubule bundles in axons of Drosophila and Xenopus neurons, we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17abca2879f65f60eb95a33dfe6642b
https://doaj.org/article/c5e8e8f422334f6baa0209cb9072db39
https://doaj.org/article/c5e8e8f422334f6baa0209cb9072db39
Publikováno v:
Neural Development, Vol 14, Iss 1, Pp 1-28 (2019)
Neural Development
Hahn, I, Voelzmann, A, Liew, Y T, Costa Gomes, B & Prokop, A 2019, ' The model of local axon homeostasis-explaining the role and regulation of microtubule bundles in axon maintenance and pathology ', Neural Development, vol. 14, no. 11, 10.1186/s13064-019-0134-0 . https://doi.org/10.1186/s13064-019-0134-0
Neural Development
Hahn, I, Voelzmann, A, Liew, Y T, Costa Gomes, B & Prokop, A 2019, ' The model of local axon homeostasis-explaining the role and regulation of microtubule bundles in axon maintenance and pathology ', Neural Development, vol. 14, no. 11, 10.1186/s13064-019-0134-0 . https://doi.org/10.1186/s13064-019-0134-0
Axons are the slender, cable-like, up to meter-long projections of neurons that electrically wire our brains and bodies. In spite of their challenging morphology, they usually need to be maintained for an organism's lifetime. This makes them key lesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3888fa799dc945b2f630712a614cef51
http://link.springer.com/article/10.1186/s13064-019-0134-0
http://link.springer.com/article/10.1186/s13064-019-0134-0
Autor:
Anna L. Munro, Ines Hahn, Ryan J. H. West, Stuart Pickering-Brown, Richard A. Baines, Joanne L. Sharpe, André Voelzmann
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Hahn, I, Sharpe, J, Voelzmann, A, Munro, A, Baines, R, Pickering-Brown, S & West, R 2020, ' Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-and combination-specific phenotypic profiles in Drosophila ', Acta Neuropathologica Communications, vol. 8, no. 158 . https://doi.org/10.1186/s40478-020-01028-y
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Hahn, I, Sharpe, J, Voelzmann, A, Munro, A, Baines, R, Pickering-Brown, S & West, R 2020, ' Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-and combination-specific phenotypic profiles in Drosophila ', Acta Neuropathologica Communications, vol. 8, no. 158 . https://doi.org/10.1186/s40478-020-01028-y
A large intronic hexanucleotide repeat expansion (GGGGCC) within the C9orf72 (C9orf72-SMCR8 Complex Subunit) locus is the most prevalent genetic cause of both Frontotemporal Dementia (FTD) and Motor Neuron Disease (MND). In patients this expansion is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d42ac9e36c8afe30209b02288df1ed
http://europepmc.org/articles/PMC7487709
http://europepmc.org/articles/PMC7487709
Autor:
Franka Eckardt, Mariangela Sociale, Kathrin Klee, Margret H. Bülow, Melanie Thielisch, Bernadette Breiden, André Voelzmann, Anna-Lena Wulf, Joachim L. Schultze, Reinhard Bauer, Konrad Sandhoff, Nadine Weinstock, Sinah Löbbert, Julia Sellin
Publikováno v:
Cell Reports, Vol 22, Iss 4, Pp 967-978 (2018)
Sociale, M, Wulf, A-L, Breiden, B, Klee, K, Thielisch, M, Eckardt, F, Sellin, J, Bülow, M H, Löbbert, S, Weinstock, N, Voelzmann, A, Schultze, J, Sandhoff, K & Bauer, R 2018, ' Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements ', Cell Reports, vol. 22, no. 4, pp. 967-978 . https://doi.org/10.1016/j.celrep.2017.12.090
Sociale, M, Wulf, A-L, Breiden, B, Klee, K, Thielisch, M, Eckardt, F, Sellin, J, Bülow, M H, Löbbert, S, Weinstock, N, Voelzmann, A, Schultze, J, Sandhoff, K & Bauer, R 2018, ' Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements ', Cell Reports, vol. 22, no. 4, pp. 967-978 . https://doi.org/10.1016/j.celrep.2017.12.090
Maintenance of metabolic homeostasis requires adaption of gene regulation to the cellular energy state via transcriptional regulators. Here, we identify a role of ceramide synthase (CerS) Schlank, a multiple transmembrane protein containing a catalyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f785b9c74fd4ea4c7a340e314d00f8ea
http://www.sciencedirect.com/science/article/pii/S2211124717319277
http://www.sciencedirect.com/science/article/pii/S2211124717319277