Zobrazeno 1 - 10
of 56
pro vyhledávání: '"André Van Helvoort Lengert"'
Autor:
João Guilherme de Moraes Pontes, Milka Jadranin, Márcia Regina Assalin, Melissa Quintero Escobar, Danijela Stanisic, Tássia Brena Barroso Carneiro Costa, André van Helvoort Lengert, Érica Boldrini, Sandra Regina Morini da Silva, Daniel Onofre Vidal, Leticia Huan Bacellar Liu, Mariana Maschietto, Ljubica Tasic
Publikováno v:
Metabolites, Vol 14, Iss 8, p 416 (2024)
Cancer is a complex disease that can also affect the younger population; however, it is responsible for a relatively high mortality rate of children and youth, especially in low- and middle-income countries (LMICs). Besides that, lipidomic studies in
Externí odkaz:
https://doaj.org/article/f7f9be87f6014fd3bedd136612ff9226
Autor:
Sara Ferreira Pires, Juliana Sobral de Barros, Silvia Souza da Costa, Gabriel Bandeira do Carmo, Marília de Oliveira Scliar, André van Helvoort Lengert, Érica Boldrini, Sandra Regini Morini da Silva, Daniel Onofre Vidal, Mariana Maschietto, Ana Cristina Victorino Krepischi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10463 (2023)
Osteosarcoma (OS) is the most prevalent type of bone tumor, but slow progress has been achieved in disentangling the full set of genomic events involved in its initiation and progression. We assessed by NGS the mutational spectrum of 28 primary OSs f
Externí odkaz:
https://doaj.org/article/91cde52289b94dd983e39e9e470680a4
Autor:
André van Helvoort Lengert, Leticia do Nascimento Braga Pereira, Eduardo Ramos Martins Cabral, Izabela Natalia Faria Gomes, Lais Machado de Jesus, Maria Fernanda Santiago Gonçalves, Aline Oliveira da Rocha, Tiago Alexandre Tassinari, Luciane Sussuchi da Silva, Ana Carolina Laus, Daniel Onofre Vidal, Mariana Tomazini Pinto, Rui Manuel Reis, Luiz Fernando Lopes
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 8, p 245 (2022)
Background: Testicular germ cell tumors (TGCTs), a group of heterogeneous neoplasms, are the most frequent tumors of teenagers and young men, with the incidence rising worldwide. High cure rates can be achieved through cisplatin (CDDP)-based treatmen
Externí odkaz:
https://doaj.org/article/8070914a654247999fa9aa215ce7e518
Autor:
Renato José da Silva-Oliveira, Izabela Natalia Faria Gomes, Luciane Sussuchi da Silva, André van Helvoort Lengert, Ana Carolina Laus, Matias Eliseo Melendez, Carla Carolina Munari, Fernanda de Paula Cury, Giovanna Barbarini Longato, Rui Manuel Reis
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7774 (2022)
Background: EGFR mutations are present in approximately 15–50% of non-small cell lung cancer (NSCLC), which are predictive of anti-EGFR therapies. At variance, NSCLC patients harboring KRAS mutations are resistant to those anti-EGFR approaches. Afa
Externí odkaz:
https://doaj.org/article/d9e3b221eeda4a2a8528926ddeb4a25d
Autor:
Leonardo César de Freitas Cayres, Larissa Vedovato Vilela de Salis, Guilherme Siqueira Pardo Rodrigues, André van Helvoort Lengert, Ana Paula Custódio Biondi, Larissa Donadel Barreto Sargentini, João Luiz Brisotti, Eleni Gomes, Gislane Lelis Vilela de Oliveira
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Hashimoto thyroiditis (HT) is the most common autoimmune disease worldwide, characterized by chronic inflammation and circulating autoantibodies against thyroid peroxidase and thyroglobulin. Patients require hormone replacement with oral levothyroxin
Externí odkaz:
https://doaj.org/article/7e6d6ac700fb4f498b95830e5c9c0f24
Autor:
Diego Luis Ribeiro, Katiuska Tuttis, Larissa Cristina Bastos de Oliveira, Juliana Mara Serpeloni, Izabela Natalia Faria Gomes, André van Helvoort Lengert, Cláudia Quintino da Rocha, Rui Manuel Reis, Ilce Mara de Syllos Cólus, Lusânia Maria Greggi Antunes
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 963 (2022)
Metastatic prostate cancer (mPCa) is resistant to several chemotherapeutic agents. Brachydin A (BrA), a glycosylated flavonoid extracted from Fridericia platyphylla, displays a remarkable antitumoral effect against in vitro mPCa cells cultured as bid
Externí odkaz:
https://doaj.org/article/4103b00b4aa24c56aa0ab2528370ac2c
Autor:
Sahlua Miguel Volc, Cíntia Regina Niederauer Ramos, Henrique de Campos Reis Galvão, Paula Silva Felicio, Aline Silva Coelho, Gustavo Noriz Berardineli, Natalia Campacci, Cristina da Silva Sabato, Lucas Faria Abrahao-Machado, Iara Viana Vidigal Santana, Nathalia Campanella, André van Helvoort Lengert, Daniel Onofre Vidal, Rui Manuel Reis, Caio F Dantas, Robson C Coelho, Erica Boldrini, Sergio Vicente Serrano, Edenir Inêz Palmero
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227260 (2020)
Sarcomas represent less than 1% of all solid neoplasms in adults and over 20% in children. Their etiology is unclear, but genetic susceptibility plays an important role in this scenario. Sarcoma is central in Li-Fraumeni Syndrome (LFS), a familial pr
Externí odkaz:
https://doaj.org/article/211ea98f438a42eb99e7b1a1cf8e8b58
Autor:
Izabela N. F. Gomes, Renato J. da Silva-Oliveira, Luciane Sussuchi da Silva, Olga Martinho, Adriane F. Evangelista, André van Helvoort Lengert, Letícia Ferro Leal, Viviane Aline Oliveira Silva, Stéphanie Piancenti dos Santos, Flávia Caroline Nascimento, André Lopes Carvalho, Rui Manuel Reis
Publikováno v:
Cells, Vol 11, Iss 1, p 154 (2022)
Cetuximab is the sole anti-EGFR monoclonal antibody that is FDA approved to treat head and neck squamous cell carcinoma (HNSCC). However, no predictive biomarkers of cetuximab response are known for HNSCC. Herein, we address the molecular mechanisms
Externí odkaz:
https://doaj.org/article/c72f8685c0814c25b7bf993a42594fde
Autor:
Krepischi, Sara Ferreira Pires, Juliana Sobral de Barros, Silvia Souza da Costa, Gabriel Bandeira do Carmo, Marília de Oliveira Scliar, André van Helvoort Lengert, Érica Boldrini, Sandra Regini Morini da Silva, Daniel Onofre Vidal, Mariana Maschietto, Ana Cristina Victorino
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10463
Osteosarcoma (OS) is the most prevalent type of bone tumor, but slow progress has been achieved in disentangling the full set of genomic events involved in its initiation and progression. We assessed by NGS the mutational spectrum of 28 primary OSs f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::63b1371db1412bbfe26f376794a2b668
Autor:
Rhafaela Causin, André Van Helvoort Lengert, Izabela Gomes, Ana De Freitas, Marcela Rosa, Ricardo Dos Reis, Rui Reis, Márcia Marques
Publikováno v:
Oncology Reports. 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b422db4fa8c4a34d0c4f2018b278f0c
https://doi.org/10.3892/or.2023.8546
https://doi.org/10.3892/or.2023.8546