Zobrazeno 1 - 3
of 3
pro vyhledávání: '"André T. S. Vicente"'
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Leukemia is a heterogeneous group of life‐threatening malignant disorders of the hematopoietic system. Immunotherapy, radiotherapy, stem cell transplantation, targeted therapy, and chemotherapy are among the approved leukemia treatments. U
Externí odkaz:
https://doaj.org/article/bf8c0c69d4d841d6a744bc6d0947a707
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Cancer is a leading cause of mortality responsible for an estimated 10 million deaths worldwide in 2020, and its incidence has been rapidly growing over the last decades. Population growth and aging, as well as high systemic toxicity and chemoresista
Externí odkaz:
https://doaj.org/article/e46468c5b35b4d2c97b9e0b37488b68b
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11068 (2022)
Proteolysis-targeting chimeras (PROTACs) are molecules that selectively degrade a protein of interest (POI). The incorporation of ligands that recruit mouse double minute 2 (MDM2) into PROTACs, forming the so-called MDM2-based PROTACs, has shown prom
Externí odkaz:
https://doaj.org/article/871fea6e8cf04683a18301bff80ceb9c