Zobrazeno 1 - 10
of 551
pro vyhledávání: '"André Schneider"'
Autor:
Corinne von Känel, Philip Stettler, Carmela Esposito, Stephan Berger, Simona Amodeo, Silke Oeljeklaus, Salvatore Calderaro, Ignacio M Durante, Vendula Rašková, Bettina Warscheid, André Schneider
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002449 (2024)
Protein import and genome replication are essential processes for mitochondrial biogenesis and propagation. The J-domain proteins Pam16 and Pam18 regulate the presequence translocase of the mitochondrial inner membrane. In the protozoan Trypanosoma b
Externí odkaz:
https://doaj.org/article/64ab8f152b6f436f85439cad12bc2318
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113112- (2023)
Summary: The protozoan parasite Trypanosoma brucei and its disease-causing relatives are among the few organisms that barely regulate the transcription of protein-coding genes. Yet, alterations in its gene expression are essential to survive in diffe
Externí odkaz:
https://doaj.org/article/f01a082714b74bf7a759d684535811fd
Autor:
Nastasja Merle, Sabrina Elmshäuser, Florian Strassheimer, Michael Wanzel, Alexander M. König, Julianne Funk, Michelle Neumann, Katharina Kochhan, Frederik Helmprobst, Axel Pagenstecher, Andrea Nist, Marco Mernberger, André Schneider, Thomas Braun, Tilman Borggrefe, Rajkumar Savai, Oleg Timofeev, Thorsten Stiewe
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-22 (2022)
Abstract Background In vivo gene editing of somatic cells with CRISPR nucleases has facilitated the generation of autochthonous mouse tumors, which are initiated by genetic alterations relevant to the human disease and progress along a natural timeli
Externí odkaz:
https://doaj.org/article/d980d18d5f1b484f966f534df0c944fb
Autor:
Caroline E. Dewar, Silke Oeljeklaus, Jan Mani, Wignand W. D. Mühlhäuser, Corinne von Känel, Johannes Zimmermann, Torsten Ochsenreiter, Bettina Warscheid, André Schneider
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Mitochondria import most of their proteins posttranslationally. Here, Dewar et al. characterize the mitochondrial quality control mechanism of Trypanosoma brucei. Through proteomics and functional studies, they show that only ablation of ATOM69, one
Externí odkaz:
https://doaj.org/article/3b2387b2f9184a889fa3ce9cdccdc488
Autor:
Bernd Schimanski, Salome Aeschlimann, Philip Stettler, Sandro Käser, Maria Gomez-Fabra Gala, Julian Bender, Bettina Warscheid, F-Nora Vögtle, André Schneider
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010207 (2022)
The protist parasite Trypanosoma brucei has a single mitochondrion with a single unit genome termed kinetoplast DNA (kDNA). Faithfull segregation of replicated kDNA is ensured by a complicated structure termed tripartite attachment complex (TAC). The
Externí odkaz:
https://doaj.org/article/da159221ac3a4a81b4191be7262d143d
Autor:
Advaitha Iyer, Moritz Niemann, Mauro Serricchio, Caroline E Dewar, Silke Oeljeklaus, Luce Farine, Bettina Warscheid, André Schneider, Peter Bütikofer
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1009717 (2022)
The endoplasmic reticulum membrane complex (EMC) is a versatile complex that plays a key role in membrane protein biogenesis in the ER. Deletion of the complex has wide-ranging consequences including ER stress, disturbance in lipid transport and orga
Externí odkaz:
https://doaj.org/article/edba199df9bf463bb92e660f78d35e86
Autor:
Alessandro Ianni, Michael Hofmann, Poonam Kumari, Shahriar Tarighi, Hamza M Al-Tamari, André Görgens, Bernd Giebel, Hendrik Nolte, Marcus Krüger, Isabelle Salwig, Soni Savai Pullamsetti, Andreas Günther, André Schneider, Thomas Braun
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Idiopathic pulmonary fibrosis (IPF) represents the most aggressive form of pulmonary fibrosis (PF) and is a highly debilitating disorder with a poorly understood etiology. The lung epithelium seems to play a critical role in the initiation and progre
Externí odkaz:
https://doaj.org/article/6fce2c61a703482688fe3b0f7a3637b5
Autor:
Roger Fricker, Rebecca Brogli, Hannes Luidalepp, Leander Wyss, Michel Fasnacht, Oliver Joss, Marek Zywicki, Mark Helm, André Schneider, Marina Cristodero, Norbert Polacek
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Trypanosoma brucei mainly relies on translational regulation to adjust gene expression, but details are unclear. Here the authors show that, under stress conditions, tRNAThr half level increases, associates with ribosomes and polysomes, and stimulate
Externí odkaz:
https://doaj.org/article/1d23c87897e1460f9d583fc47617f772
Publikováno v:
Energies, Vol 15, Iss 13, p 4922 (2022)
In the course of the switch to renewable energy sources, there is a shift from a few large energy sources (power plants) to a large number of small, distributed energy sources (e.g., photovoltaic systems) and energy storage devices (e.g., electric ve
Externí odkaz:
https://doaj.org/article/68b7bfefb0fc42e8a754b1aca4992640
Publikováno v:
Sensors, Vol 21, Iss 19, p 6536 (2021)
This paper presents a novel approach for Multi-Robot Task Allocation (MRTA) that introduces priority policies on preemptive task scheduling and considers dependencies between tasks, and tolerates faults. The approach is referred to as Multi-Robot Pre
Externí odkaz:
https://doaj.org/article/ae33be39f8ca4014ab661a076589c1d8