Zobrazeno 1 - 6
of 6
pro vyhledávání: '"André R. Paquette"'
Autor:
André R. Paquette, Sterling R. Payne, Geoffrey A. McKay, Jordan T. Brazeau-Henrie, Micheal G. Darnowski, Anitha Kammili, Federico Bernal, Thien-Fah Mah, Samantha Gruenheid, Dao Nguyen, Christopher N. Boddy
Publikováno v:
RSC Medicinal Chemistry. 13:445-455
Optimized RpoN-based stapled peptides selectively bind promoter DNA sequence and inhibit virulence of Pseudomonas aeruginosa in an in vivo model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dba7e113a6d590d6fe5209babed9e7b5
https://doi.org/10.1039/d1md00371b
https://doi.org/10.1039/d1md00371b
Publikováno v:
The Journal of organic chemistry. 87(22)
The natural product armeniaspirol possesses a unique spirocyclic N,O-ketal in an α,β-dichloro-α,β-unsaturated lactam scaffold that has proved challenging to synthesize. Herein, we characterize the oxidative chlorination of pyrrole-2-carboxylate d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691fcef0ebf19c2c3d563741a0704653
https://pubmed.ncbi.nlm.nih.gov/36322913
https://pubmed.ncbi.nlm.nih.gov/36322913
Autor:
Jordan T. Brazeau-Henrie, André R. Paquette, Allison Q. O’Rourke, Michael G. Darnowski, Christopher N. Boddy
Publikováno v:
Organic letters. 24(35)
The total and chemoenzymatic synthesis of the depsipeptide natural product seongsanamide E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ebc15155bfaf192281139a2ed22590
https://pubmed.ncbi.nlm.nih.gov/36006794
https://pubmed.ncbi.nlm.nih.gov/36006794
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 84:129210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95c027861307442ef9e571d9d25ce1c8
https://doi.org/10.1016/j.bmcl.2023.129210
https://doi.org/10.1016/j.bmcl.2023.129210
Autor:
André R, Paquette, Sterling R, Payne, Geoffrey A, McKay, Jordan T, Brazeau-Henrie, Micheal G, Darnowski, Anitha, Kammili, Federico, Bernal, Thien-Fah, Mah, Samantha, Gruenheid, Dao, Nguyen, Christopher N, Boddy
Publikováno v:
RSC Med Chem
Stapled peptides have the ability to mimic α-helices involved in protein binding and have proved to be effective pharmacological agents for disrupting protein–protein interactions. DNA-binding proteins such as transcription factors bind their cogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3900fc49366b67abb1dccde6e4c96262
https://pubmed.ncbi.nlm.nih.gov/35647551
https://pubmed.ncbi.nlm.nih.gov/35647551
Autor:
Michael G. Darnowski, Taylor D. Lanosky, Puneet Labana, Jordan T. Brazeau-Henrie, Nicholas D. Calvert, Mark H. Dornan, Claudia Natola, André R. Paquette, Adam J. Shuhendler, Christopher N. Boddy
Publikováno v:
RSC Med Chem
Antibiotics with fundamentally new mechanisms of action such as the armeniaspirols, which target the ATP-dependent proteases ClpXP and ClpYQ, must be developed to combat antimicrobial resistance. While the mechanism of action of armeniaspirol against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9d7950759b93d172b4195fd09d1a3d
https://pubmed.ncbi.nlm.nih.gov/35647545
https://pubmed.ncbi.nlm.nih.gov/35647545