Zobrazeno 1 - 10
of 67
pro vyhledávání: '"André P Fay"'
Autor:
Joaquim Bellmunt, Lillian Werner, Jeffrey J Leow, Stephanie A Mullane, André P Fay, Markus Riester, Paul Van Hummelen, Mary-Ellen Taplin, Toni K Choueiri, Eliezer Van Allen, Jonathan Rosenberg
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0124711 (2015)
An integrative analysis was conducted to identify genomic alterations at a pathway level that could predict overall survival (OS) in patients with advanced urothelial carcinoma (UC) treated with platinum-based chemotherapy.DNA and RNA were extracted
Externí odkaz:
https://doaj.org/article/1fd80159b5854ca09a8f19092b7bfff3
Autor:
Joaquim Bellmunt, Shamini Selvarajah, Scott Rodig, Marta Salido, Silvia de Muga, Irmgard Costa, Beatriz Bellosillo, Lillian Werner, Stephanie Mullane, André P Fay, Robert O'Brien, Jordi Barretina, André E Minoche, Sabina Signoretti, Clara Montagut, Heinz Himmelbauer, David M Berman, Philip Kantoff, Toni K Choueiri, Jonathan E Rosenberg
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103325 (2014)
BACKGROUND: Anaplastic lymphoma kinase (ALK) genomic alterations have emerged as a potent predictor of benefit from treatment with ALK inhibitors in several cancers. Currently, there is no information about ALK gene alterations in urothelial carcinom
Externí odkaz:
https://doaj.org/article/bbf5118d3ed9435c9fbb95822615c00c
Autor:
Marcelle Morais dos Santos, Antonio Luiz Frasson, Vinicius Duval da Silva, Aluísio de Castro Antunes Maciel, Guilherme Watte, Gustavo Werutsky, Tomás Reinert, André Poisl Fay
Publikováno v:
Revista Brasileira de Ginecologia e Obstetrícia, Vol 45, Iss 9, Pp 535-541 (2023)
Abstract Objective Breast cancer (BC) biomarkers, such as hormone receptors expression, are crucial to guide therapy in BC patients. Antiandrogens have been studied in BC; however, limited data are available on androgen receptor (AR) expression test
Externí odkaz:
https://doaj.org/article/677ae8e826ca4096966447b7aa1f5c02
Autor:
Lorelei A. Mucci, Jacob Vinson, Theresa Gold, Travis Gerke, Julie Filipenko, Rebecca M. Green, Simon G. Anderson, Simone Badal, Anders Bjartell, Kim N. Chi, Ian D. Davis, Deborah Enting, André P. Fay, John Lazarus, Joaquin Mateo, Ray McDermott, Folakemi T. Odedina, David Olmos, Aurelius Omlin, Ademola A. Popoola, Camille Ragin, Robin Roberts, Kjell M. Russnes, Charles Waihenya, Konrad H. Stopsack, Terry Hyslop, Paul Villanti, Philip W. Kantoff, Daniel J. George
Publikováno v:
JCO Global Oncology, Vol , Iss 8 (2022)
PURPOSETo describe a newly established international registry recruiting diverse patients with advanced prostate cancer across academic and community practices to address unmet needs in this population.PATIENTS AND METHODSInitiated in 2017, IRONMAN (
Externí odkaz:
https://doaj.org/article/c2ac1375880a4f8296dca71b57375939
Autor:
Sylvan C. Baca, Cassandra Singler, Soumya Zacharia, Ji-Heui Seo, Tunc Morova, Faraz Hach, Yi Ding, Tommer Schwarz, Chia-Chi Flora Huang, Jacob Anderson, André P. Fay, Cynthia Kalita, Stefan Groha, Mark M. Pomerantz, Victoria Wang, Simon Linder, Christopher J. Sweeney, Wilbert Zwart, Nathan A. Lack, Bogdan Pasaniuc, David Y. Takeda, Alexander Gusev, Matthew L. Freedman
Publikováno v:
Nature genetics, vol 54, iss 9
Nat Genet
Nature Genetics, 54(9), 1364-1375. Nature Publishing Group
Nature Genetics
Nat Genet
Nature Genetics, 54(9), 1364-1375. Nature Publishing Group
Nature Genetics
Many genetic variants affect disease risk by altering context-dependent gene regulation. Such variants are difficult to study mechanistically using current methods that link genetic variation to steady-state gene expression levels, such as expression
Autor:
Vinicius Knackfuss Gonçalves, Fernando Sabino Marques Monteiro, Antonia Angeli Gazola, Felipe Pizzolo, Júlia Elisa Hübner, Rodrigo Pellegrini, Alessandra Borba, André P. Fay
Publikováno v:
Kidney Cancer. 6:129-136
BACKGROUND: Immune checkpoint inhibitors (ICI) have shown clinical benefit among patients with advanced kidney cancer. Their cost burden hardens its access, especially in low- and middle-income countries. To set solutions, the impact of geographical
Autor:
Sabina Signoretti, Gordon J. Freeman, David F. McDermott, Toni K. Choueiri, F. Stephen Hodi, Michael B. Atkins, Rupal S. Bhatt, Ingrid Carvo, Jiaxi Song, André P. Fay, Elizabeth M. Genega, Su-Chun Cheng, Mamta Gupta, Laurence Albiges, Marcella Callea
PD-L1 positivity in relation to tumor grade within individual lesions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7bb7ccbf0fb065ffe8ca80b1abe40c
https://doi.org/10.1158/2326-6066.22538789
https://doi.org/10.1158/2326-6066.22538789
Autor:
Sabina Signoretti, Gordon J. Freeman, David F. McDermott, Toni K. Choueiri, F. Stephen Hodi, Michael B. Atkins, Rupal S. Bhatt, Ingrid Carvo, Jiaxi Song, André P. Fay, Elizabeth M. Genega, Su-Chun Cheng, Mamta Gupta, Laurence Albiges, Marcella Callea
PD-L1 expression in primary clear-cell renal cell carcinoma (ccRCC) increases the likelihood of response to anti–PD-1 inhibition, but fails to identify all responders. We hypothesized that PD-L1 levels assessed in randomly selected areas of the pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96b1e39a7ea18ec3216615a1feb2717
https://doi.org/10.1158/2326-6066.c.6548894
https://doi.org/10.1158/2326-6066.c.6548894
Autor:
Sabina Signoretti, Gordon J. Freeman, David F. McDermott, Toni K. Choueiri, F. Stephen Hodi, Michael B. Atkins, Rupal S. Bhatt, Ingrid Carvo, Jiaxi Song, André P. Fay, Elizabeth M. Genega, Su-Chun Cheng, Mamta Gupta, Laurence Albiges, Marcella Callea
Time interval between the resection of the primary tumor and the resection of each metastatic lesion. The discordance in PD-L1 expression between the primary tumor and each metastasis is also noted.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5041a00b2043a1f5e63e0c2713ec009f
https://doi.org/10.1158/2326-6066.22538792.v1
https://doi.org/10.1158/2326-6066.22538792.v1
Autor:
Robert J. Motzer, Thomas Powles, Paul de Souza, Lini Pandite, Thai H. Ho, Peter Benson, Christopher Carpenter, Keith Deen, Robert Gagnon, Yuan Liu, Sabina Signoretti, André P. Fay, David J. Figueroa, Toni K. Choueiri
Supplementary Table S1, Figures S1-2. Supplementary Table S1. Comparison of treatment outcomes between the overall study population of the COMPARZ trial and the PD-L1 study population. Supplementary Figure S1. CD8+ T cells scoring system. Supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cd51891d6b5fb38681f92b26dd7b64
https://doi.org/10.1158/1078-0432.22461738
https://doi.org/10.1158/1078-0432.22461738