Zobrazeno 1 - 10
of 23
pro vyhledávání: '"André Liesener"'
Autor:
Iris-Tatjana Kolassa, Alexander Karabatsiakis, Patrick Fissler, Alexander Woll, Franka Thurm, Christine A. F. von Arnim, Patrick Weydt, Bastian Hengerer, Martina Zügel, Andreas Borta, Björn von Einem, Olivia C. Küster, Sina Pleiner, Daria Laptinskaya, Cathrin Schnack, Verena Nold, André Liesener
Publikováno v:
Journal of Alzheimer's Disease. 59:1097-1111
Psychosocial stress and physical, cognitive, and social activity predict the risk of cognitive decline and dementia. The aim of this study was to elucidate brain-derived neurotrophic factor (BDNF), irisin, and the kynurenine pathway (KP) as potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618bfa02fb7a30e5a5b19a1860c12dee
https://doi.org/10.3233/jad-170447
https://doi.org/10.3233/jad-170447
Autor:
Claudia Dallinger, Peter Stopfer, Kristell Marzin, Rolf Kaiser, André Liesener, Dirk Trommeshauser
Publikováno v:
The Journal of Clinical Pharmacology. 56:1387-1394
Nintedanib, a triple angiokinase inhibitor, has undergone clinical investigation for the treatment of solid tumors and idiopathic pulmonary fibrosis. Nintedanib (Vargatef(®) ) plus docetaxel is approved in the EU for the treatment of patients with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a73efeec1bdd05af736569792d7f86df
https://doi.org/10.1002/jcph.752
https://doi.org/10.1002/jcph.752
Autor:
Kelly A. Allers, Kelly Doolin, Thomas Frodl, André Liesener, Sina Pleiner, Darren Roddy, Chloe Farrell, Andrew Harkin, Erik O'Hanlon, Leonardo Tozzi, Veronica O'Keane
Publikováno v:
Psychoneuroendocrinology 95, 8-17 (2018). doi:10.1016/j.psyneuen.2018.05.019
Background Tryptophan depletion is a well-replicated biological finding in Major Depressive Disorder (MDD). The kynurenine pathway (KP) and its rate-limiting tryptophan degrading enzyme, indolamine 2,3 dioxygenase (IDO), have been implicated in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609c0f4dc45f853336ce055b49f4cb51
https://pub.dzne.de/record/140233
https://pub.dzne.de/record/140233
Autor:
Heiko Hayen, Anna-Maria Perchuc, Uwe Karst, Reto Schöni, Marianne Wilmer, Martin Vogel, Mathijs Siemerink, Nils Helge Schebb, André Liesener
Publikováno v:
Rapid Communications in Mass Spectrometry. 24:687-697
A new robust high-performance liquid chromatography/electrospray ionization mass spectrometry (HPLC/ESI-MS)-based screening method for angiotensin-converting enzyme (ACE)-inhibiting substances in crude samples is described. The ACE assay is carried o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18466e90b5905947acc9103e8a98beb
https://doi.org/10.1002/rcm.4428
https://doi.org/10.1002/rcm.4428
Publikováno v:
Mass Spectrometry in Medicinal Chemistry: Applications in Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b3e1ac3b7292a3d792ff30728492b4d
https://doi.org/10.1002/9783527610907.ch8
https://doi.org/10.1002/9783527610907.ch8
Autor:
Marianne Wilmer, André Liesener, Anna-Maria Perchuc, Reto Schöni, Uwe Karst, Nils Helge Schebb
Publikováno v:
Pure and applied chemistry, 79(12), 2339-2349. IUPAC Secretariat
An electrospray ionization/mass spectrometry (ESI/MS)-based assay for the determination of acetylcholinesterase (AChE)-inhibiting activity in snake venom was developed. It allows the direct monitoring of the natural AChE substrate acetylcholine (AC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387f84436461cf05c5651a16332d704b
https://doi.org/10.1351/pac200779122339
https://doi.org/10.1351/pac200779122339
Autor:
André Liesener, Uwe Karst
Publikováno v:
Journal of separation science, 28(14), 1658-1665. Wiley-VCH Verlag
Turbulent flow chromatography (TFC) is presented as a means to reduce ion suppression in simultaneous multianalyte mass spectrometric bioassays. In this study, the effects of enzymes present in the sample on the signal response of five analytes were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8291153d7d5ff5449a00038982cbfd15
https://doi.org/10.1002/jssc.200500090
https://doi.org/10.1002/jssc.200500090
Publikováno v:
Analytica chimica acta, 543(1-2), 137-142. Elsevier
Fluorescence and mass spectrometric detection schemes are developed and compared for the simultaneous activity determination of two enzymes in solution. As model system, the following reactions are used: The alkaline phosphatase catalyzed reaction wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c10a822426020a53de7d7d3fd5a031
https://doi.org/10.1016/j.aca.2005.04.038
https://doi.org/10.1016/j.aca.2005.04.038
Publikováno v:
Rapid Communications in Mass Spectrometry. 19:2923-2928
A multiplexed mass spectrometry based assay scheme for the simultaneous determination of five different substrate/product pairs was developed as a tool for screening of proteolytic activities in snake venom fractions from Bothrops moojeni. The assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd54d8737291674143ab2fe5d1c8585
https://doi.org/10.1002/rcm.2136
https://doi.org/10.1002/rcm.2136
Publikováno v:
Analytical chemistry, 75(4), 922-926. American Chemical Society
A new methodological approach for the determination of monosubstituted phenols is described. After liquid chromatographic separation of the analytes, an on-line electrochemical derivatization is carried out and the reaction products are detected fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d3c2c07669015065e9b601278b90b9
https://doi.org/10.1021/ac0204808
https://doi.org/10.1021/ac0204808