Zobrazeno 1 - 10
of 32
pro vyhledávání: '"André L. Stein"'
Autor:
Maria Helena Fermiano, Amarith Rodrigues das Neves, Fernanda da Silva, Manuella Salustiano Andrade Barros, Camila Barbosa Vieira, André L. Stein, Tiago Elias Allievi Frizon, Antonio Luiz Braga, Carla Cardozo Pinto de Arruda, Eduardo Benedetti Parisotto, Sumbal Saba, Jamal Rafique, Thalita Bachelli Riul
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 213 (2024)
Leishmaniasis remains a significant global health concern, with current treatments relying on outdated drugs associated with high toxicity, lengthy administration, elevated costs, and drug resistance. Consequently, the urgent need for safer and more
Externí odkaz:
https://doaj.org/article/704cbb757fff493d9b1cb0ba22b67510
Autor:
Juliana Trevisan da Rocha, Tuane Bazanella Sampaio, Caroline B. Quines, Cristina W. Nogueira, André L. Stein, Gilson Zeni
Publikováno v:
Journal of Cellular Biochemistry. 118:1144-1150
Organoselenium compounds and isoquinoline derivatives have their toxicity linked to induction of pro-oxidant situations. δ-Aminolevulinate dehydratase (δ-ALA-D) and Na+ , K+ -ATPase have sulfhydryl groups susceptible to oxidation. Thus, we investig
Autor:
Juliana Trevisan da Rocha, Marina Prigol, João Rocha, Gilson Zeni, Rogério de Aquino Saraiva, Cristina W. Nogueira, Pablo Froner Nogara, André L. Stein, Tuane Bazanella Sampaio
Publikováno v:
Journal of Molecular Neuroscience. 59:135-145
Isoquinolines are formed endogenously as metabolites of neurotransmitters and are studied because they have structures similar to neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and selegiline, a selective inhibitor of MAO-B. This study inves
Publikováno v:
European Journal of Organic Chemistry. 2015:5640-5648
We have described the application of iron(III) chloride and diorganyl diselenides as cooperative partners in the cyclization of (2-aminoaryl)-2-ynols for the regioselective synthesis of 3-organoseleno quinolines. The optimized reaction conditions wer
Publikováno v:
Advanced Synthesis & Catalysis. 357:1221-1228
The dibutyl diselenide-mediated reaction furnishes symmetrical and unsymmetrical selenophenes under mild conditions.
Publikováno v:
Chemical Communications. 51:15522-15525
We reported herein the regio- and stereoselective palladium-catalyzed cross-coupling reactions of unsaturated organoselenides with Sonogashira, Suzuki, Negishi and Kumada partners. The reactions were in general carried out with Pd(PPh3)4 (10 mol%), i
Publikováno v:
Advanced Synthesis & Catalysis. 356:501-508
Autor:
André L. Stein, Bibiana Mozzaquatro Gai, Marta Maria Medeiros Frescura Duarte, Gilson Zeni, Cristiani F. Bortolatto, Suélen Osório Heck, Cristina W. Nogueira
Publikováno v:
Psychopharmacology. 231:2119-2130
3-(4-Fluorophenylselenyl)-2,5-diphenylselenophene (F-DPS) is a promising organoselenium compound that shows antidepressant-like properties related to interaction with the serotonergic system.In this study, a mouse model of anxiety/depressant-like beh
Autor:
Angélica S. Reis, Cristiane Luchese, André L. Stein, Mikaela P. Pinz, Gilson Zeni, Ethel A. Wilhelm, Ana Teresinha Ferreira, Ane G. Vogt
Publikováno v:
Anais da Academia Brasileira de Ciências, Volume: 89, Issue: 1 Supplement, Pages: 457-467, Published: 22 MAY 2017
Anais da Academia Brasileira de Ciências, Vol 89, Iss 1 suppl, Pp 457-467
Anais da Academia Brasileira de Ciências v.89 n.1 suppl.0 2017
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Anais da Academia Brasileira de Ciências, Vol 89, Iss 1 suppl, Pp 457-467
Anais da Academia Brasileira de Ciências v.89 n.1 suppl.0 2017
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
The present study investigated the antioxidant effect of a new class of quinoline derivatives (a-d) on assays in vitro. Lipid peroxidation, thiol peroxidase-like and free radical scavenging activities were determined to evaluate antioxidant activity
Publikováno v:
ChemInform. 47
We reported herein the regio- and stereoselective palladium-catalyzed cross-coupling reactions of unsaturated organoselenides with Sonogashira, Suzuki, Negishi and Kumada partners. The reactions were in general carried out with Pd(PPh3)4 (10 mol%), i