Zobrazeno 1 - 10
of 20
pro vyhledávání: '"André L. P. Candéa"'
Autor:
Marcelle L. F. Bispo, Camilo H. S. Lima, Laura N. F. Cardoso, André L. P. Candéa, Flávio A. F. M. Bezerra, Maria C. S. Lourenço, Maria G. M. O. Henriques, Ricardo B. Alencastro, Carlos R. Kaiser, Marcus V. N. Souza, Magaly G. Albuquerque
Publikováno v:
Pharmaceuticals, Vol 10, Iss 2, p 52 (2017)
In an ongoing research program for the development of new anti-tuberculosis drugs, we synthesized three series (A, B, and C) of 7-chloro-4-aminoquinolines, which were evaluated in vitro against Mycobacterium tuberculosis (MTB). Now, we report the ant
Externí odkaz:
https://doaj.org/article/1bd0b3f01c1141e3a7d926e13ac67d2d
Autor:
Daniely Correa-Moreira, André L. P. Candéa, Fernanda Nazaré Morgado, Joseli Oliveira-Ferreira, Maria das Graças de Oliveira Henriques, Balwan Singh, Josué da Costa Lima-Junior, Alberto Moreno, Paula Melo de-Luca, Mary R. Galinski, Rodrigo Nunes Rodrigues-da-Silva, Isabela Ferreira Soares, Paulo Renato Rivas Totino
Publikováno v:
Vaccine. 37:306-313
Plasmodium vivax Merozoite Surface Protein-9 (PvMSP-9) is a malaria vaccine candidate naturally immunogenic in humans and able to induce high antibody titers in animals when delivered as a recombinant protein. Recently, we identified the sequence EAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404f1d7ed858d2cc6d2e52bab9930308
https://doi.org/10.1016/j.vaccine.2018.10.016
https://doi.org/10.1016/j.vaccine.2018.10.016
Autor:
Mariana C. Souza, Tatiana Almeida Pádua, André L. P. Candéa, João Luiz Silva-Filho, Maria Fernanda Souza Costa, Patricia R. M. Rocco, Fabio T. M. Costa, Johnatas D. Silva, Maria das Graças M. O. Henriques, Natalia Torres
Publikováno v:
Journal of Leukocyte Biology. 103:657-670
Acute lung injury (ALI) models are characterized by neutrophil accumulation, tissue damage, alteration of the alveolar capillary membrane, and physiological dysfunction. Lipoxin A4 (LXA4) is an anti-inflammatory eicosanoid that was demonstrated to at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73b7db6bcedd76e741b9d9d58d9f13ab
https://doi.org/10.1002/jlb.3a1016-435rrr
https://doi.org/10.1002/jlb.3a1016-435rrr
Autor:
Jonathas Xavier Pereira, Marcellus Dias da Costa, Edward Helal-Neto, Maria das Graças M. O. Henriques, André L. P. Candéa, Fiammetta Nigro, Ralph Santos-Oliveira, Filipe Leal Portilho, Eduardo Ricci-Júnior, Suyene Rocha Pinto
Publikováno v:
Drug delivery and translational research. 9(1)
In this study, we developed, characterized, and tested in vivo polymeric nanoparticle of ethambutol labeled with 99mTc as nanoradiopharmaceutical for early diagnosis of tuberculosis by single-photon emission computed tomography, also as a therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97af024ee2693074c9fe6e55ac739d3d
https://pubmed.ncbi.nlm.nih.gov/30178280
https://pubmed.ncbi.nlm.nih.gov/30178280
Autor:
Maria Fernanda de Souza Costa, Leonardo J M Carvalho, Maria das Graças M. O. Henriques, André L. P. Candéa, Eduardo Tibiriçá, Leonardo N. Seito, Natalia Torres, Vanessa Estato, Ana Acacia S. Pinheiro, Carmen Penido, Barbara Antunes, Celso Caruso-Neves, Leandro L. da Silva, Mariana C. Souza, Thadeu Maramaldo, Tatiana Almeida Pádua
Publikováno v:
International Immunopharmacology. 24(2):400-407
A breakdown of the brain–blood barrier (BBB) due to endothelial dysfunction is a primary feature of cerebral malaria (CM). Lipoxins (LX) are specialized pro-resolving mediators that attenuate endothelial dysfunction in different vascular beds. It h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c8c4e1c837b5423debd10e96773b36
Autor:
Tatiana A, Pádua, Natalia D, Torres, André L P, Candéa, Maria Fernanda Souza, Costa, Johnatas D, Silva, João Luiz, Silva-Filho, Fabio T M, Costa, Patricia R M, Rocco, Mariana C, Souza, Maria G, Henriques
Publikováno v:
Journal of leukocyte biology. 103(4)
Acute lung injury (ALI) models are characterized by neutrophil accumulation, tissue damage, alteration of the alveolar capillary membrane, and physiological dysfunction. Lipoxin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c19ecc0e024eb7c3fe36512a6f7cfca
https://pubmed.ncbi.nlm.nih.gov/29345368
https://pubmed.ncbi.nlm.nih.gov/29345368
Autor:
Tatiana Almeida Pádua, André L. P. Candéa, Magaiver Andrade Silva, Maria das Graças M. O. Henriques, Elaine Cruz Rosas, Luana Barbosa Correa, Leonardo N. Seito, Thadeu Estevam Moreira Maramaldo Costa
Publikováno v:
Journal of natural products. 79(6)
Methyl gallate (MG) is a prevalent phenolic acid in the plant kingdom, and its presence in herbal medicines might be related to its remarkable biological effects, such as its antioxidant, antitumor, and antimicrobial activities. Although some indirec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c43bbbd63dc49972fe146989c269ac6
https://pubmed.ncbi.nlm.nih.gov/27227459
https://pubmed.ncbi.nlm.nih.gov/27227459
Autor:
André L. P. Candéa, Thais Cristina Mendonça Nogueira, Marcus V. N. de Souza, Edson Ferreira da Silva, Carlos R. Kaiser, Maria das Graças M. O. Henriques, Larisse de Oliveira Feitosa, Samir A. Carvalho, Alessandra C. Pinheiro, Maria C.S. Lourenço
Publikováno v:
Medicinal Chemistry. 7:611-623
A series of 32 L-serinyl hydrazone derivatives have been synthesized and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv, being also evaluated their cell viabilities in non infected and infected macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d431bdd36357ca2a6c70cf5866d60b2a
https://doi.org/10.2174/157340611797928325
https://doi.org/10.2174/157340611797928325
Autor:
Flávio A. F. M. Bezerra, André L. P. Candéa, Carlos R. Kaiser, M. C. S. Lourenco, Marcelle de Lima Ferreira, Camilo Henrique da Silva Lima, Maria das Graças M. O. Henriques, M. V. N. de Souza
Publikováno v:
Medicinal Chemistry. 7:245-249
A series of nine N'-(E)-heteroaromatic-pyrazine-2-carbohydrazide derivatives (5a-f and 6a-c) have been synthesized and evaluated against M. tuberculosis ATCC 27294 using the micro plate Alamar Blue assay (MABA), being the activities expressed as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f281d7823a6374d1c11dc0df6680b683
https://doi.org/10.2174/157340611795564303
https://doi.org/10.2174/157340611795564303
Autor:
André L. P. Candéa, Carlos R. Kaiser, Sílvia Helena Cardoso, Maria das Graças M. O. Henriques, Maria C.S. Lourenço, Milena Barbosa Barreto, Marcus V. N. de Souza
Publikováno v:
Chemical Biology & Drug Design. 77:489-493
The present article describes a series of 21 N ¢-benzylidene-2-oxo-2H-chromene-3-carbohydrazides 4a–4v, which were synthesized and evaluated for their cell viabilities in non-infected and Mycobacterium bovis Bacillus Calmette–Guerin-infected mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89a55d2e8bfdff1812b35832ee29e0db
https://doi.org/10.1111/j.1747-0285.2011.01120.x
https://doi.org/10.1111/j.1747-0285.2011.01120.x