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pro vyhledávání: '"André L. Lira"'
Autor:
André L. Lira, Natasha Mina, Camila R. Bonturi, Ruben S. Nogueira, Ricardo J. S. Torquato, Maria Luiza V. Oliva, Alioscka A. Sousa
Publikováno v:
Chemical Research in Toxicology. 35:1558-1569
Ultrasmall gold nanoparticles (usNPs) and nanoclusters are an emerging class of nanomaterials exhibiting distinctive physicochemical properties and
Autor:
André L. Lira, Tia C.L. Kohs, Samantha A. Moellmer, Joseph J. Shatzel, Owen J.T. McCarty, Cristina Puy
Publikováno v:
Seminars in Thrombosis and Hemostasis.
Coagulation factor XI (FXI) has increasingly been shown to play an integral role in several physiologic and pathological processes. FXI is among several zymogens within the blood coagulation cascade that are activated by proteolytic cleavage, with FX
Publikováno v:
Langmuir. 36:7991-8001
Nanomaterials displaying well-tailored sizes and surface chemistries can provide novel ways with which to modulate the structure and function of enzymes. Recently, we showed that gold nanoparticles (AuNPs) in the ultrasmall size regime could perform
Publikováno v:
Nanoscale. 12:19230-19240
To date, extensive effort has been devoted toward the characterization of protein interactions with synthetic nanostructures. However, much remains to be understood, particularly concerning microscopic mechanisms of interactions. Here, we have conduc
Akademický článek
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Autor:
Ricardo J.S. Torquato, Peter Schuck, Alioscka A. Sousa, Rodrigo da Silva Ferreira, André L. Lira
Publikováno v:
The Journal of Physical Chemistry C. 123:28450-28459
Gold nanoparticles (NPs) in the ultrasmall size regime provide a new paradigm in the way that nanomaterials can be used to regulate protein structure and function. However, the rational design of u...
Autor:
Rodrigo da Silva Ferreira, Alioscka A. Sousa, Peter Schuck, Maria Luiza Vilela Oliva, André L. Lira, Ricardo J.S. Torquato
Publikováno v:
Nanoscale Advances
The enzymatic activity of α-thrombin was allosterically regulated by interactions with ultrasmall gold nanoparticles.
The catalytic activity of enzymes can be regulated by interactions with synthetic nanoparticles (NPs) in a number of ways. To
The catalytic activity of enzymes can be regulated by interactions with synthetic nanoparticles (NPs) in a number of ways. To
Autor:
Huaying Zhao, Rodrigo da Silva Ferreira, Alioscka A. Sousa, Peter Schuck, Sergio A. Hassan, Ricardo J.S. Torquato, Maria Luiza Vilela Oliva, André L. Lira
Publikováno v:
Nanoscale. 10:3235-3244
Synthetic ultrasmall nanoparticles (NPs) can be designed to interact with biologically active proteins in a controlled manner. However, the rational design of NPs requires a clear understanding of their interactions with proteins and the precise mole