Zobrazeno 1 - 10
of 14
pro vyhledávání: '"André L S Cruz"'
Autor:
Luana da Silva Gomes, Érica de Oliveira Costa, Thuany G. Duarte, Thiago S. Charret, Raquel C. Castiglione, Rafael L. Simões, Vinicius D. B. Pascoal, Thiago H. Döring, Fernando de C. da Silva, Vitor F. Ferreira, Aldo S. de Oliveira, Aislan C. R. F. Pascoal, André L. S. Cruz, Vanessa Nascimento
Publikováno v:
ACS Omega, Vol 9, Iss 20, Pp 21948-21963 (2024)
Externí odkaz:
https://doaj.org/article/bd4613bdbe7049f9a9d988849e43e4a5
Autor:
Tandressa S. Berguetti, Lucas S. P. Quintaes, Thais Hancio Pereira, Marcela C. Robaina, André L. S. Cruz, Raquel C. Maia, Paloma Silva de Souza
Publikováno v:
Cells, Vol 8, Iss 5, p 500 (2019)
P-glycoprotein (Pgp/ABCB1) overexpression is associated with multidrug resistance (MDR) phenotype and, consequently, failure in cancer chemotherapy. However, molecules involved in cell death deregulation may also support MDR. Tumor necrosis factor-al
Externí odkaz:
https://doaj.org/article/f5fa7807c09a4cadabd74c4a34d556ea
Autor:
Patrícia T. Bozza, João P. B. Viola, André L S Cruz, Ester A. Barreto, Narayana P. B. Fazolini
Publikováno v:
Cell Death and Disease, Vol 11, Iss 2, Pp 1-16 (2020)
Cell Death & Disease
Cell Death & Disease
Lipid droplets (also known as lipid bodies) are lipid-rich, cytoplasmic organelles that play important roles in cell signaling, lipid metabolism, membrane trafficking, and the production of inflammatory mediators. Lipid droplet biogenesis is a regula
Autor:
Luis F Ribeiro-Pinto, Nina Carrossini, André L S Cruz, Patrícia T. Bozza, Leonardo K. Teixeira, João P. B. Viola
Publikováno v:
Molecular and Cellular Biology
Intracellular lipid accumulation has been associated with a poor prognosis in cancer. We have previously reported the involvement of lipid droplets in cell proliferation in colon cancer cells, suggesting a role for these organelles in cancer developm
Autor:
João P. B. Viola, Patrícia T. Bozza, Narayana P. B. Fazolini, André L S Cruz, Clarissa M. Maya-Monteiro, Miriam B. F. Werneck
Publikováno v:
Cell Cycle
Accumulating evidence suggests that obesity and enhanced inflammatory reactions are predisposing conditions for developing colon cancer. Obesity is associated with high levels of circulating leptin. Leptin is an adipocytokine that is secreted by adip
Publikováno v:
Cancer Science
Multidrug resistance (MDR) is considered a multifactorial event that favors cancer cells becoming resistant to several chemotherapeutic agents. Numerous mechanisms contribute to MDR, such as P-glycoprotein (Pgp/ABCB1) activity that promotes drug effl
Autor:
Flávia Castello Branco Vidal, João P. B. Viola, André L S Cruz, Wallace Martins de Araújo, Marcelo Neves Tanaka, José Andrés Morgado-Díaz
Publikováno v:
International journal of oncology. 38(5)
Lithium is a specific inhibitor of GSK3-β, and hence, an activator of the Wnt/β-catenin pathway, whereas the epidermal growth factor (EGF) has been linked to malignant transformation in epithelial cancer cells. Both pathways are aberrantly activate
Nuclear factor of activated T cells (NFAT) was first described as an activation and differentiation transcription factor in lymphocytes. Several in vitro studies suggest that NFAT family members are redundant proteins. However, analysis of mice defic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3d70eaf2f1fbed0558e6d89fc91e42
https://europepmc.org/articles/PMC2593389/
https://europepmc.org/articles/PMC2593389/
Publikováno v:
Cancer Research. 73:1744-1744
Background: Lipid bodies (also known as lipid droplets) are organelles involved in lipid turnover, membrane traffic and intracellular signaling. Lipogenesis has been associated with poor prognosis in several neoplasic diseases, suggesting a role for
Publikováno v:
Cancer Research. 73:879-879
Background: Multidrug resistance (MDR) is associated with unsuccessful clinical cancer treatment. Different proteins are enhanced in MDR including the efflux pump P-glycoprotein (Pgp/MDR1) and inhibitor of apoptosis proteins (IAP). Newly, it has been