Zobrazeno 1 - 10
of 85
pro vyhledávání: '"André Hanauer"'
Autor:
Charlotte Castillon, Steeve Lunion, Nathalie Desvignes, André Hanauer, Serge Laroche, Roseline Poirier
Publikováno v:
Neurobiology of Disease, Vol 115, Iss , Pp 69-81 (2018)
Adult neurogenesis is involved in certain hippocampus-dependent cognitive functions and is linked to psychiatric diseases including intellectual disabilities. The Coffin-Lowry syndrome (CLS) is a developmental disorder caused by mutations in the Rsk2
Externí odkaz:
https://doaj.org/article/38b820d4632d43709f513d0229d759cb
Autor:
Elise Morice, Séverine Farley, Roseline Poirier, Glenn Dallerac, Carine Chagneau, Solange Pannetier, André Hanauer, Sabrina Davis, Cyrille Vaillend, Serge Laroche
Publikováno v:
Neurobiology of Disease, Vol 58, Iss , Pp 156-168 (2013)
The Coffin–Lowry syndrome (CLS) is a syndromic form of intellectual disability caused by loss-of-function of the RSK2 serine/threonine kinase encoded by the rsk2 gene. Rsk2 knockout mice, a murine model of CLS, exhibit spatial learning and memory i
Externí odkaz:
https://doaj.org/article/77281fa05613408aa5d345f70f9bf238
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 2, Pp 3358-3375 (2013)
The RSK2 protein is a member of the RSK serine-threonine protein kinase family and is encoded by the X-linked rps6ka3 gene in human. Highly heterogeneous loss-of-function mutations affecting this gene are responsible for a severe syndromic form of co
Externí odkaz:
https://doaj.org/article/40d6ebc538a8462a994128dbd4a427e9
Autor:
Virginie Laugel-Haushalter, Marie Paschaki, Pauline Marangoni, Coralie Pilgram, Arnaud Langer, Thibaut Kuntz, Julie Demassue, Supawich Morkmued, Philippe Choquet, André Constantinesco, Fabien Bornert, Matthieu Schmittbuhl, Solange Pannetier, Laurent Viriot, André Hanauer, Pascal Dollé, Agnès Bloch-Zupan
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84343 (2014)
BackgroundThe RSK2 gene is responsible for Coffin-Lowry syndrome, an X-linked dominant genetic disorder causing mental retardation, skeletal growth delays, with craniofacial and digital abnormalities typically associated with this syndrome. Craniofac
Externí odkaz:
https://doaj.org/article/59354c677b234ef4aa0e1bfbf8185d97
Autor:
Diego Gomez-Nicola, Rossana Zaru, André Hanauer, Stephen P. Matthews, Alexander J. Edgar, Alan R. Prescott, Colin Watts
Publikováno v:
The Journal of Immunology Author Choice
Langerhans cells (LC), the dendritic cells of the epidermis, are distributed in a distinctive regularly spaced array. In the mouse, the LC array is established in the first few days of life from proliferating local precursors, but the regulating sign
Publikováno v:
Molecular and Cellular Biology
Rsk kinases play important roles in several cellular processes such as proliferation, metabolism, and migration. Until recently, Rsk activation was thought to be exclusively initiated by Erk1/2, but in dendritic cells (DC) Rsk is also activated by p3
Autor:
André Hanauer, Charlotte Castillon, Roseline Poirier, Serge Laroche, Steeve Lunion, Nathalie Desvignes
Publikováno v:
Neurobiology of Disease, Vol 115, Iss, Pp 69-81 (2018)
Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2018, 115, pp.69-81. ⟨10.1016/j.nbd.2018.04.007⟩
Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2018, 115, pp.69-81. ⟨10.1016/j.nbd.2018.04.007⟩
International audience; Adult neurogenesis is involved in certain hippocampus-dependent cognitive functions and is linked to psychiatric diseases including intellectual disabilities. The Coffin-Lowry syndrome (CLS) is a developmental disorder caused
Autor:
Marjorie Gayanilo, Hrishikesh Thakur, Michael S. Kapiloff, Catherine L. Passariello, Joshua M. Hare, Joshua B. Danial, Andrew V. Le, André Hanauer, Jennifer J. Carlisle Michel, Alejandra Negro, Kimberly L. Dodge-Kafka, Michael D. Kritzer, Behzad N. Oskouei, Michael Sanders, Jinliang Li
Publikováno v:
Circulation Research. 112:128-139
Rationale: Cardiac myocyte hypertrophy is the main compensatory response to chronic stress on the heart. p90 ribosomal S6 kinase (RSK) family members are effectors for extracellular signal-regulated kinases that induce myocyte growth. Although increa
Publikováno v:
Epstein's Inborn Errors of Development: The Molecular Basis of Clinical Disorders of Morphogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4faa38fc03e88f2bfd4079680a00f9c
https://doi.org/10.1093/med/9780199934522.003.0146
https://doi.org/10.1093/med/9780199934522.003.0146
Autor:
André Hanauer, Katia Befort, Solange Pannetier, Emmanuel Darcq, Brigitte L. Kieffer, Claire Gaveriaux-Ruff, Pascale Koebel, Megan K. Mahoney
Publikováno v:
Neuropsychopharmacology. 37:1288-1296
It has been established that mu opioid receptors activate the ERK1/2 signaling cascade both in vitro and in vivo. The Ser/Thr kinase RSK2 is a direct downstream effector of ERK1/2 and has a role in cellular signaling, cell survival growth, and differ