Zobrazeno 1 - 10
of 106
pro vyhledávání: '"André Görgens"'
Autor:
Emine Begüm Gençer, Yuk Kit Lor, Fawaz Abomaray, Samir El Andaloussi, Maria Pernemalm, Nidhi Sharma, Daniel W Hagey, André Görgens, Manuela O Gustafsson, Katarina Le Blanc, Mawaddah Asad Toonsi, Lilian Walther-Jallow, Cecilia Götherström
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Mesenchymal stem/stromal cells (MSCs) can regenerate tissues through engraftment and differentiation but also via paracrine signalling via extracellular vesicles (EVs). Fetal-derived MSCs (fMSCs) have been shown, both in vitro and
Externí odkaz:
https://doaj.org/article/54fa88addc4b496387c5dedc29fe0c11
Autor:
Vivian V. T. Nguyen, Joshua A. Welsh, Tobias Tertel, Andre Choo, Simonides I. van deWakker, Kyra A. Y. Defourny, Bernd Giebel, Pieter Vader, Jayanthi Padmanabhan, Sai Kiang Lim, Esther N. M. Nolte‐'t Hoen, Marianne C. Verhaar, R. Beklem Bostancioglu, Antje M. Zickler, Jia Mei Hong, Jennifer C. Jones, Samir EL Andaloussi, Bas W. M. vanBalkom, André Görgens
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Mesenchymal stromal cells (MSCs) are promising regenerative therapeutics that primarily exert their effects through secreted extracellular vesicles (EVs). These EVs – being small and non‐living – are easier to handle and possess advant
Externí odkaz:
https://doaj.org/article/ae35180078c5434b854c0344b3d59bb2
Autor:
Wenyi Zheng, Julia Rädler, Helena Sork, Zheyu Niu, Samantha Roudi, Jeremy P. Bost, André Görgens, Ying Zhao, Doste R. Mamand, Xiuming Liang, Oscar P. B. Wiklander, Taavi Lehto, Dhanu Gupta, Joel Z. Nordin, Samir EL Andaloussi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Extracellular vesicles (EVs) are gaining ground as next-generation drug delivery modalities. Genetic fusion of the protein of interest to a scaffold protein with high EV-sorting ability represents a robust cargo loading strategy. To address
Externí odkaz:
https://doaj.org/article/622f51f2cad347f4917ee57145e74779
Autor:
Chen Li, Chengxi Sun, Warangkana Lohcharoenkal, Mohamad Moustafa Ali, Pengwei Xing, Wenyi Zheng, André Görgens, Manuela O. Gustafsson, Samir EL Andaloussi, Enikö Sonkoly, Andor Pivarcsi
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Cutaneous squamous cell carcinoma (cSCC) is a fast-increasing cancer with metastatic potential. Extracellular vesicles (EVs) are small membrane-bound vesicles that play important roles in intercellular communication, particularly in the tumo
Externí odkaz:
https://doaj.org/article/832e44aa5da14b3eabc1c21bfb2a2a2d
Autor:
Simonides Immanuel van deWakker, Julia Bauzá‐Martinez, Carla Ríos Arceo, Herak Manjikian, Christian Jamie Bernard Snijders Blok, Marieke Theodora Roefs, Eduard Willms, Renee Goverdina Catharina Maas, Matti Feije Pronker, Olivier Gerrit deJong, Wei Wu, André Görgens, Samir El Andaloussi, Joost Petrus Gerardus Sluijter, Pieter Vader
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Cardiac progenitor cell (CPC)‐derived small extracellular vesicles (sEVs) exhibit great potential to stimulate cardiac repair. However, the multifaceted nature of sEV heterogeneity presents a challenge in understanding the distinct mechani
Externí odkaz:
https://doaj.org/article/216f54e574094a04966cba7e541ce4bb
Autor:
Daniel W. Hagey, Egle Kvedaraite, Mira Akber, André Görgens, Joman Javadi, Tatiana von Bahr Greenwood, Caroline Björklund, Selma Olsson Åkefeldt, Tova Hannegård-Hamrin, Henrik Arnell, Katalin Dobra, Nikolas Herold, Mattias Svensson, Samir EL Andaloussi, Jan-Inge Henter, Magda Lourda
Publikováno v:
Haematologica, Vol 108, Iss 9 (2023)
Langerhans cell histiocytosis (LCH) is a potentially life-threatening inflammatory myeloid neoplasia linked to pediatric neurodegeneration, whereby transformed LCH cells form agglomerated lesions in various organs. Although MAP-kinase pathway mutatio
Externí odkaz:
https://doaj.org/article/73b3716c5fc848519e01566ce7fbf090
Autor:
Joshua A. Welsh, Ger J. A. Arkesteijn, Michel Bremer, Michael Cimorelli, Françoise Dignat‐George, Bernd Giebel, André Görgens, An Hendrix, Martine Kuiper, Romaric Lacroix, Joanne Lannigan, Ton G. vanLeeuwen, Estefanía Lozano‐Andrés, Shoaib Rao, Stéphane Robert, Leonie deRond, Vera A. Tang, Tobias Tertel, Xiaomei Yan, Marca H. M. Wauben, John P. Nolan, Jennifer C. Jones, Rienk Nieuwland, Edwin van derPol
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells, which are larger than EVs. Whereas cells exceed the backgroun
Externí odkaz:
https://doaj.org/article/d32b6861d7e84dd8a1fd500dfda89593
Autor:
Ghulam Hassan Dar, Cláudia C. Mendes, Wei-Li Kuan, Alfina A. Speciale, Mariana Conceição, André Görgens, Inna Uliyakina, Miguel J. Lobo, Wooi F. Lim, Samir EL Andaloussi, Imre Mäger, Thomas C. Roberts, Roger A. Barker, Deborah C. I. Goberdhan, Clive Wilson, Matthew J. A. Wood
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
GAPDH is generally considered a housekeeping gene and functions in glycolysis. Here, the authors show that GAPDH has a role in promoting vesicle clustering in endosomes and can load siRNA onto the surface of extracellular vesicles, which can be explo
Externí odkaz:
https://doaj.org/article/b286aa9a491c4fbfb8a3ac8161e8f868
Autor:
André Görgens, Giulia Corso, Daniel W. Hagey, Rim Jawad Wiklander, Manuela O. Gustafsson, Ulrika Felldin, Yi Lee, R. Beklem Bostancioglu, Helena Sork, Xiuming Liang, Wenyi Zheng, Dara K. Mohammad, Simonides I. van de Wakker, Pieter Vader, Antje M. Zickler, Doste R. Mamand, Li Ma, Margaret N. Holme, Molly M. Stevens, Oscar P. B. Wiklander, Samir EL Andaloussi
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 6, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological processes and hold great potential for therapeutic and diagnostic use. Despite significant advances within the last decade, the key issue of EV storage
Externí odkaz:
https://doaj.org/article/b0afdd0ac68d4599b414eeb023f4d490
Autor:
Daniel W. Hagey, Maximilian Kordes, André Görgens, Metoboroghene O. Mowoe, Joel Z. Nordin, Carlos Fernández Moro, J.‐Matthias Löhr, Samir EL Andaloussi
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 12, Pp n/a-n/a (2021)
Abstract Up to now, the field of liquid biopsies has focused on circulating tumour DNA and cells, though extracellular vesicles (EVs) have been of increasing interest in recent years. Thus, reported sources of tumour‐derived nucleic acids include l
Externí odkaz:
https://doaj.org/article/7da1754bd96c4fbb8751c3cd8bf11ab9