Zobrazeno 1 - 10
of 17
pro vyhledávání: '"André Franken"'
Autor:
Hailun Liu, André Franken, Alexandra P. Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer, Nadia Stamm
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Decidualization of endometrial cells is the prerequisite for embryo implantation and subsequent placenta formation and is induced by rising progesterone levels following ovulation. One of the hormone receptors contributing to endo
Externí odkaz:
https://doaj.org/article/1dbb22213ddc43528911c90156f44bbb
Ultra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis
Autor:
Nikolas H. Stoecklein, Georg Fluegen, Rosa Guglielmi, Rui P.L. Neves, Thilo Hackert, Emrullah Birgin, Stefan A. Cieslik, Monica Sudarsanam, Christiane Driemel, Guus van Dalum, André Franken, Dieter Niederacher, Hans Neubauer, Tanja Fehm, Jutta M. Rox, Petra Böhme, Lena Häberle, Wolfgang Göring, Irene Esposito, Stefan A. Topp, Frank A.W. Coumans, Jürgen Weitz, Wolfram T. Knoefel, Johannes C. Fischer, Ulrich Bork, Nuh N. Rahbari
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-7 (2023)
Abstract The limited sensitivity of circulating tumor cell (CTC) detection in pancreatic adenocarcinoma (PDAC) stems from their extremely low concentration in the whole circulating blood, necessitating enhanced detection methodologies. This study sou
Externí odkaz:
https://doaj.org/article/5c1826cd9d794cc9bba8643ba9c0536e
Autor:
Florian Reinhardt, Luisa Coen, Mahdi Rivandi, André Franken, Eunike Sawitning Ayu Setyono, Tobias Lindenberg, Jens Eberhardt, Tanja Fehm, Dieter Niederacher, Franziska Knopf, Hans Neubauer
Publikováno v:
Cancers, Vol 15, Iss 22, p 5411 (2023)
Circulating tumor cells (CTCs) serve as crucial metastatic precursor cells, but their study in animal models has been hindered by their low numbers. To address this challenge, we present DanioCTC, an innovative xenograft workflow that overcomes the s
Externí odkaz:
https://doaj.org/article/cbe24de60d4f4a04920635402338f45c
Autor:
Yingxue Bai, Marina Ludescher, Gereon Poschmann, Kai Stühler, Martine Wyrich, Julia Oles, André Franken, Mahdi Rivandi, Anna Abramova, Florian Reinhardt, Eugen Ruckhäberle, Dieter Niederacher, Tanja Fehm, Michael A. Cahill, Nadia Stamm, Hans Neubauer
Publikováno v:
Cancers, Vol 13, Iss 22, p 5635 (2021)
In previous studies, we reported that progesterone receptor membrane component 1 (PGRMC1) is implicated in progestin signaling and possibly associated with increased breast cancer risk upon combined hormone replacement therapy. To gain mechanistic in
Externí odkaz:
https://doaj.org/article/6a9e08196bd446198cfebd6c4010e315
Autor:
André Franken, Bianca Behrens, Florian Reinhardt, Liwen Yang, Mahdi Rivandi, Francesco Marass, Bernadette Jaeger, Natalia Krawczyk, Jan-Philipp Cieslik, Ellen Honisch, Hannah Asperger, Emmanuelle Jeannot, Charlotte Proudhon, Niko Beerenwinkel, Natali Schölermann, Irene Esposito, Frederic Dietzel, Nikolas H. Stoecklein, Dieter Niederacher, Tanja Fehm, Hans Neubauer
Publikováno v:
Cancers, Vol 13, Iss 23, p 6004 (2021)
Background: The analysis of liquid biopsies, e.g., circulating tumor cells (CTCs) is an appealing diagnostic concept for targeted therapy selection. In this proof-of-concept study, we aimed to perform multiparametric analyses of CTCs to select target
Externí odkaz:
https://doaj.org/article/165fd1f96cfc4a9e81bb07db07ae51a9
Autor:
Sarah A. Jeffreys, Branka Powter, Bavanthi Balakrishnar, Kelly Mok, Patsy Soon, André Franken, Hans Neubauer, Paul de Souza, Therese M. Becker
Publikováno v:
Cells, Vol 9, Iss 9, p 2077 (2020)
Therapy of hormone receptor positive breast cancer (BCa) generally targets estrogen receptor (ER) function and signaling by reducing estrogen production or by blocking its interaction with the ER. Despite good long-term responses, resistance to treat
Externí odkaz:
https://doaj.org/article/668bd848d82e4018be35bb985c7619ad
Autor:
André Franken, Mahdi Rivandi, Liwen Yang, Bernadette Jäger, Natalia Krawczyk, Ellen Honisch, Dieter Niederacher, Tanja Fehm, Hans Neubauer
Publikováno v:
Applied Sciences, Vol 10, Iss 10, p 3364 (2020)
Targeted therapy has become the preferred approach to treat most cancers, including metastatic breast cancer. Using liquid biopsies, which can act as a dynamic diagnostic tool, is an appealing concept to identify effective therapies. In order to iden
Externí odkaz:
https://doaj.org/article/41fba2b4633b42e3aa4282bc13f6a738
Publikováno v:
Tumor Biology, Vol 39 (2017)
The majority of breast cancers are hormone receptor positive due to the expression of the estrogen and/or progesterone receptors. Endocrine therapy is a major treatment option for all disease stages of hormone receptor–positive breast cancer and im
Externí odkaz:
https://doaj.org/article/e04303f530e541acbbedf64715bc0c75
Autor:
Florian Reinhardt, André Franken, Franziska Meier-Stiegen, Christiane Driemel, Nikolas H. Stoecklein, Johannes C. Fischer, Dieter Niederacher, Eugen Ruckhaeberle, Tanja Fehm, Hans Neubauer
Publikováno v:
Cancers, Vol 11, Iss 7, p 903 (2019)
Circulating tumor cells (CTCs) hold great promise with regard to prognosis, treatment optimization, and monitoring of breast cancer patients. Single CTC transcriptome profiling might help reveal valuable information concerning intra-patient heterogen
Externí odkaz:
https://doaj.org/article/837d2fc545244e4db9f9c133b2c7d164
Autor:
Rita Lampignano, Liwen Yang, Martin H. D. Neumann, André Franken, Tanja Fehm, Dieter Niederacher, Hans Neubauer
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 9, p 1885 (2017)
Circulating tumor cells (CTCs), potential precursors of most epithelial solid tumors, are mainly enriched by epithelial cell adhesion molecule (EpCAM)-dependent technologies. Hence, these approaches may overlook mesenchymal CTCs, considered highly ma
Externí odkaz:
https://doaj.org/article/5e3a650143f047c0b68cd99719934673