Výsledky vyhledávání - "André F. Pina"

Identification of novel aptamers targeting cathepsin B-overexpressing prostate cancer cells

Autor: Ana Cláudia Pereira, André F. Pina, Diana Sousa, Débora Ferreira, Cátia Santos-Pereira, Joana L. Rodrigues, Luís D. R. Melo, Goreti Sales, Sérgio F. Sousa, Lígia R. Rodrigues

Publikováno v: Molecular Systems Design & Engineering. 7:637-650

For the first time, an aptamer that specifically binds to cathepsin B (CatB)-overexpressing prostate cancer cells was identified by combining SELEX and computational tools.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::727fceca19140ae94cac58bf929a91b8
https://doi.org/10.1039/d2me00022a

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Non-B DNA conformations analysis through molecular dynamics simulations

Autor: André F. Pina, Sérgio F. Sousa, Luísa Azevedo, João Carneiro

Publikováno v: Biochimica et biophysica acta. General subjects. 1866(12)

Non-B DNA conformations are molecular structures that do not follow the canonical DNA double helix. Mutagenetic instability in nuclear and mitochondrial DNA (mtDNA) genomes has been associated with simple non-B DNA conformations, as hairpins or more

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e76c182a3a2d676552331db02232e1b
https://pubmed.ncbi.nlm.nih.gov/36216170

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Cover Feature: The Catalytic Mechanism of Pdx2 Glutaminase Driven by a Cys‐His‐Glu Triad: A Computational Study (ChemBioChem 9/2022)

Autor: André F. Pina, Sérgio F. Sousa, Nuno M. F. S. A. Cerqueira

Publikováno v: ChemBioChem. 23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8950d1a6cc46640eb8d82007007ccb2
https://doi.org/10.1002/cbic.202200024

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