Zobrazeno 1 - 10
of 47
pro vyhledávání: '"André F, Martins"'
Autor:
Veronica Clavijo Jordan, André F. Martins, Erica Dao, Kalotina Geraki, Sara Chirayil, Xiaodong Wen, Pooyan Khalighinejad, Daniel Parrott, Xiaojing Wang, Patricia Gonzalez Pagan, Neil Rofsky, Michael Farquharson, A. Dean Sherry
Publikováno v:
npj Imaging, Vol 2, Iss 1, Pp 1-9 (2024)
Abstract Previous studies have shown that the zinc-responsive MRI probe, GdL1, can distinguish healthy versus malignant prostate tissues based upon differences in zinc content and secretion. In this study, mice were fed chow containing low, normal, o
Externí odkaz:
https://doaj.org/article/4e0f64bbff6e47ceb4a36a4bcc8f3c65
Autor:
Jiang-Hui Meng, Yong-Biao Huang, Jin Long, Qiu-Chen Cai, Xin Qiao, Qiong-Li Zhang, Li-Dan Zhang, Xiang Yan, Rui Jing, Xing-Shan Liu, Sai-Jun Zhou, Yong-Sheng Yuan, Yin-Chen Ma, Li-Xiang Zhou, Nan-Nan Peng, Xing-Cheng Li, Cheng-Hui Cai, Hong-Mei Tang, André F. Martins, Jean X. Jiang, Kai-Jun Luo
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109469- (2024)
Summary: The extracellular superoxide dismutases (ecSODs) secreted by Microplitis bicoloratus reduce the reactive oxygen species (ROS) stimulated by the Microplitis bicoloratus bracovirus. Here, we demonstrate that the bacterial transferase hexapepti
Externí odkaz:
https://doaj.org/article/c90922ffdec84d128d3b1d6dcc1067cc
Autor:
Philipp Knopf, Dimitri Stowbur, Sabrina H. L. Hoffmann, Natalie Hermann, Andreas Maurer, Valentina Bucher, Marilena Poxleitner, Bredi Tako, Dominik Sonanini, Balaji Krishnamachary, Sanhita Sinharay, Birgit Fehrenbacher, Irene Gonzalez-Menendez, Felix Reckmann, David Bomze, Lukas Flatz, Daniela Kramer, Martin Schaller, Stephan Forchhammer, Zaver M. Bhujwalla, Leticia Quintanilla-Martinez, Klaus Schulze-Osthoff, Mark D. Pagel, Marieke F. Fransen, Martin Röcken, André F. Martins, Bernd J. Pichler, Kamran Ghoreschi, Manfred Kneilling
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L
Externí odkaz:
https://doaj.org/article/b3fa661fa2c8409a83b991ccda94efe7
Autor:
Kalotina Geraki, Michael J. Farquharson, Sara Chirayil, A. Dean Sherry, Alia Al-Ebraheem, Erica Dao, André F. Martins, Veronica Clavijo Jordan
Publikováno v:
Inorg Chem
Prostatic zinc content is a known biomarker for discriminating normal healthy tissue from benign prostatic hyperplasia (BPH) and prostate cancer (PCa). Given that zinc content is not readily measured without a tissue biopsy, we have been exploring no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d118bd25c433d52be279aeaf9e1ce8fc
https://doi.org/10.1021/acs.inorgchem.9b01132
https://doi.org/10.1021/acs.inorgchem.9b01132
Lanthanide-Based T2ex and CEST Complexes Provide Insights into the Design of pH Sensitive MRI Agents
Publikováno v:
Angewandte Chemie International Edition. 56:16626-16630
The CEST and T1 /T2 relaxation properties of a series of Eu3+ and Dy3+ DOTA-tetraamide complexes with four appended primary amine groups are measured as a function of pH. The CEST signals in the Eu3+ complexes show a strong CEST signal after the pH w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893ba4fc9eb4df03300982791f761aba
https://doi.org/10.1002/anie.201707959
https://doi.org/10.1002/anie.201707959
Lanthanide-Based T2ex and CEST Complexes Provide Insights into the Design of pH Sensitive MRI Agents
Publikováno v:
Angewandte Chemie. 129:16853-16857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b9abda34daf263569d6afc02d78f11b
https://doi.org/10.1002/ange.201707959
https://doi.org/10.1002/ange.201707959
Autor:
Yuyan Mai, André F. Martins, Lei Zhang, A. Dean Sherry, Piyu Zhao, Alexander M. Funk, Veronica Clavijo Jordan, Wei Chen, Yunkou Wu, Shanrong Zhang
Publikováno v:
Chemistry - A European Journal. 23:1752-1756
Overproduction of lactate is a hallmark of cancer, yet a method to quantitatively measure lactate production by cancer cells is not straight-forward. Chemical exchange saturation transfer magnetic resonance imaging (CEST MRI) can potentially be used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff80e634c4431ea3e5e96d37ca12283
https://doi.org/10.1002/chem.201604558
https://doi.org/10.1002/chem.201604558
Autor:
Sara Chirayil, Namini Paranawithana, Piyu Zhao, André F. Martins, Gabriele Meloni, Veronica Clavijo Jordan, A. Dean Sherry
Publikováno v:
J Am Chem Soc
The design, synthesis, and properties of a new gadolinium-based copper-responsive magnetic resonance imaging (MRI) contrast agent is presented. The sensor (GdL(1)) has high selectivity for copper ions and exhibits a 43% increase in r(1) relaxivity (2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5236ddbf41a2fac48275bf58cce6a87a
https://europepmc.org/articles/PMC9991518/
https://europepmc.org/articles/PMC9991518/
Publikováno v:
Inorganics, Vol 7, Iss 2, p 18 (2019)
Many elegant inorganic designs have been developed to aid medical imaging. We know better now how to improve imaging due to the enormous efforts made by scientists in probe design and other fundamental sciences, including inorganic chemistry, physioc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4e07ffbb24c70b44e8c3144a050264
https://www.mdpi.com/2304-6740/7/2/18
https://www.mdpi.com/2304-6740/7/2/18