Zobrazeno 1 - 10
of 12
pro vyhledávání: '"André Eichert"'
Autor:
Charlotte Förster, André Eichert, Dominik Oberthür, Christian Betzel, Reinhard Geßner, Andreas Nitsche, Jens P. Fürste
Publikováno v:
Journal of Nucleic Acids, Vol 2012 (2012)
“Locked nucleic acids” (LNAs) belong to the backbone-modified nucleic acid family. The 2′-O,4′-C-methylene-β-D-ribofuranose nucleotides are used for single or multiple substitutions in RNA molecules and thereby introduce enhanced bio- and th
Externí odkaz:
https://doaj.org/article/93ee7fccbafb4a209a2d2b9c6ad3ff93
Autor:
Charlotte Förster, Volker A. Erdmann, Reinhard Geßner, Jens P. Fürste, Dominik Oberthuer, Christian Betzel, André Eichert
Publikováno v:
Biochemical and Biophysical Research Communications. 412:532-536
tRNAs are aminoacylated by the aminoacyl-tRNA synthetases. There are at least 20 natural amino acids, but due to the redundancy of the genetic code, 64 codons on the mRNA. Therefore, there exist tRNA isoacceptors that are aminoacylated with the same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85854bdfca9cd3beeb0073fb7ce45c67
https://doi.org/10.1016/j.bbrc.2011.07.030
https://doi.org/10.1016/j.bbrc.2011.07.030
Autor:
Volker A. Erdmann, Jens P. Fürste, Charlotte Förster, Dominik Oberthuer, Christian Betzel, Andreas Nitsche, Jiang Gao, André Eichert, Frederick G. Quast
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 65:881-885
Locked nucleic acids (LNAs) are modified nucleic acids which contain a modified sugar such as beta-D-2'-O,4'-C methylene-bridged ribofuranose or other sugar derivatives in LNA analogues. The beta-D-2'-O,4'-C methylene ribofuranose LNAs in particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8d23f3f3e79a967221866e49a6204e
https://doi.org/10.1107/s1744309109029145
https://doi.org/10.1107/s1744309109029145
Autor:
Jens P. Fürste, Volker A. Erdmann, Charlotte Förster, André Eichert, Christian Betzel, Angela Schreiber, Markus Perbandt
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 65:98-101
The aminoacylation of tRNA is a crucial step in cellular protein biosynthesis. Recognition of the cognate tRNA by the correct aminoacyl-tRNA synthetase is ensured by tRNA identity elements. In tRNA(Arg), the identity elements consist of the anticodon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf04fb3ac49c701e602b5a03bb5dca84
https://doi.org/10.1107/s1744309108042012
https://doi.org/10.1107/s1744309108042012
Autor:
André Eichert, Charlotte Förster, Jens P. Fürste, Angela Schreiber, Christian Betzel, Volker A. Erdmann, Markus Perbandt
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 65:59-62
Interest has been focused on comparative X-ray structure analyses of different tRNA(Gly) acceptor-stem helices. tRNA(Gly)/glycyl-tRNA synthetase belongs to the so-called class II system, in which the tRNA identity elements consist of simple and uniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebeb38a5767d14076b625504cc3c82f
https://doi.org/10.1107/s1744309108040153
https://doi.org/10.1107/s1744309108040153
Autor:
J.P. Fürste, Volker A. Erdmann, Dominik Oberthür, André Eichert, Charlotte Förster, Ch. Betzel
Publikováno v:
Biochemical and biophysical research communications. 404(1)
tRNAs are aminoacylated with the correct amino acid by the cognate aminoacyl-tRNA synthetase. The tRNA/synthetase systems can be divided into two classes: class I and class II. Within class I, the tRNA identity elements that enable the specificity co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696a43de903ba78e9a42d126b09c5f8d
https://pubmed.ncbi.nlm.nih.gov/21114959
https://pubmed.ncbi.nlm.nih.gov/21114959
Autor:
Christian Betzel, André Eichert, Volker A. Erdmann, Jens P. Fürste, Alexander K.C. Ulrich, Charlotte Förster
Publikováno v:
Biochemical and biophysical research communications. 395(3)
We solved the X-ray structures of two Escherichia coli tRNA{sup Ser} acceptor stem microhelices. As both tRNAs are aminoacylated by the same seryl-tRNA-synthetase, we performed a comparative structure analysis of both duplexes to investigate the heli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e6a1ab8efea16bf26bc7d1d8882e56
https://pubmed.ncbi.nlm.nih.gov/20361934
https://pubmed.ncbi.nlm.nih.gov/20361934
Autor:
André Eichert, Volker A. Erdmann, Christian Betzel, Katja Behling, Jens P. Fürste, Charlotte Förster
Publikováno v:
Acta crystallographica. Section F, Structural biology and crystallization communications. 65(Pt 8)
Modified nucleic acids are of great interest with respect to their nuclease resistance and enhanced thermostability. In therapeutical and diagnostic applications, such molecules can substitute for labile natural nucleic acids that are targeted agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a591f14ff6c7e59766218e6773493e2
https://pubmed.ncbi.nlm.nih.gov/19652346
https://pubmed.ncbi.nlm.nih.gov/19652346
Autor:
Volker A. Erdmann, Jens P. Fürste, Angela Schreiber, Christian Betzel, Charlotte Förster, Markus Perbandt, André Eichert
Publikováno v:
Biochemical and biophysical research communications. 386(2)
tRNA identity elements assure the correct aminoacylation of tRNAs by the cognate aminoacyl-tRNA synthetases. tRNA Ser belongs to the so-called class II system, in which the identity elements are rather simple and are mostly located in the acceptor st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a0e3b1849b0c14c2fb25b598ae2aed
https://pubmed.ncbi.nlm.nih.gov/19527687
https://pubmed.ncbi.nlm.nih.gov/19527687
Autor:
André Eichert, Volker A. Erdmann, Jens P. Fürste, Markus Perbandt, Christian Betzel, Charlotte Förster, Dominik Oberthür, Angela Schreiber
Publikováno v:
Biochemical and biophysical research communications. 385(1)
Due to the redundancy of the genetic code there exist six mRNA codons for arginine and several tRNA(Arg) isoacceptors which translate these triplets to protein within the context of the mRNA. The tRNA identity elements assure the correct aminoacylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17641696f85e13c9669964a20820723
https://pubmed.ncbi.nlm.nih.gov/19426710
https://pubmed.ncbi.nlm.nih.gov/19426710