Zobrazeno 1 - 7
of 7
pro vyhledávání: '"André E. Nel"'
Publikováno v:
Bioengineering, Vol 10, Iss 10, p 1205 (2023)
Despite the formidable treatment challenges of pancreatic ductal adenocarcinoma (PDAC), considerable progress has been made in improving drug delivery via pioneering nanocarriers. These innovations are geared towards overcoming the obstacles presente
Externí odkaz:
https://doaj.org/article/b7f7b8a21d244039a0e61aeee9d4280a
Publikováno v:
ACS Nano
In addition to the contribution of cancer cells, the solid tumor microenvironment (TME) has a critical role in determining tumor expansion, antitumor immunity and the response to immunotherapy. Understanding the details of the complex interplay betwe
Autor:
André E. Nel Md DSc
Publikováno v:
Nano Lett
Autor:
Haiyuan, Zhang, Suman, Pokhrel, Zhaoxia, Ji, Huan, Meng, Xiang, Wang, Sijie, Lin, Chong Hyun, Chang, Linjiang, Li, Ruibin, Li, Bingbing, Sun, Meiying, Wang, Yu-Pei, Liao, Rong, Liu, Tian, Xia, Lutz, Mädler, André E, Nel
Publikováno v:
Journal of the American Chemical Society
We demonstrate through PdO doping that creation of heterojunctions on Co3O4 nanoparticles can quantitatively adjust band-gap and Fermi energy levels to study the impact of metal oxide nanoparticle semiconductor properties on cellular redox homeostasi
Autor:
Xiangsheng Liu, Jinhong Jiang, Yu‐Pei Liao, Ivanna Tang, Emily Zheng, Waveley Qiu, Matthew Lin, Xiang Wang, Ying Ji, Kuo‐Ching Mei, Qi Liu, Chong Hyun Chang, Zev A. Wainberg, Andre E. Nel, Huan Meng
Publikováno v:
Advanced Science, Vol 8, Iss 6, Pp n/a-n/a (2021)
Abstract There is an urgent need to develop new life‐prolonging therapy for pancreatic ductal adenocarcinoma (PDAC). It is demonstrated that improved irinotecan delivery by a lipid bilayer coated mesoporous silica nanoparticle, also known as a sili
Externí odkaz:
https://doaj.org/article/c08726d25ff14c68a302bfa813b306c1
Autor:
Jianqin Lu, Xiangsheng Liu, Yu-Pei Liao, Felix Salazar, Bingbing Sun, Wen Jiang, Chong Hyun Chang, Jinhong Jiang, Xiang Wang, Anna M. Wu, Huan Meng, Andre E. Nel
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Pancreatic cancer remains difficult to treat mainly due to the drug delivery challenges posed by a strong stromal component. Here the authors develop nanocarriers that improve drug delivery efficiency and engage the host immune system against the tum
Externí odkaz:
https://doaj.org/article/5f90acace1374b91a2c015209af90f64
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 4 (2017)
We demonstrated that activated transcytosis is a major mechanism to complement the classic enhanced permeability and retention effect in pancreatic cancer. This was achieved by using an iRGD peptide that triggers transcytosis pathway at the tumor sit
Externí odkaz:
https://doaj.org/article/042b5266c74a49c0b6d460b97a68ada9