Zobrazeno 1 - 10
of 232
pro vyhledávání: '"André C Carpentier"'
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177110 (2017)
Hepatocyte nuclear factor 1 alpha (HNF1α) defects cause Mature Onset Diabetes of the Young type 3 (MODY3), characterized by defects in beta-cell insulin secretion. However, HNF1α is involved in many other metabolic pathways with relevance for monog
Externí odkaz:
https://doaj.org/article/80d96c0dd2734d43b2a438d3b7cae357
Autor:
François Normand-Lauzière, Frédérique Frisch, Sébastien M Labbé, Patrick Bherer, René Gagnon, Stephen C Cunnane, André C Carpentier
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10956 (2010)
It has been proposed that abnormal postprandial plasma nonesterified fatty acid (NEFA) metabolism may participate in the development of tissue lipotoxicity and type 2 diabetes (T2D). We previously found that non-diabetic offspring of two parents with
Externí odkaz:
https://doaj.org/article/ac7a9a3922b84b06a274292f9f62fb91
Autor:
Run Zhou Ye, Emilie Montastier, Frédérique Frisch, Christophe Noll, Hugues Allard-Chamard, Nicolas Gévry, André Tchernof, André C. Carpentier
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108692- (2024)
Summary: Adipocyte hypertrophy is associated with metabolic complications independent of obesity. We aimed to determine: 1) the association between adipocyte size and postprandial fatty acid metabolism; 2) the potential mechanisms driving the obesity
Externí odkaz:
https://doaj.org/article/679ccead7b3043cbb1c81f76245c3683
Autor:
Bernard Cuenoud, Etienne Croteau, Valérie St-Pierre, Gabriel Richard, Mélanie Fortier, Camille Vandenberghe, André C. Carpentier, Stephen C. Cunnane
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Ketones are alternative energy substrates for the heart and kidney but no studies have investigated their metabolism simultaneously in both organs in humans. The present double tracer positron emission tomography (PET) study evaluated the organ distr
Externí odkaz:
https://doaj.org/article/7f946f45654446788263a0bed1e207bf
Autor:
Run Zhou Ye, Christophe Noll, Gabriel Richard, Martin Lepage, Éric E. Turcotte, André C. Carpentier
Publikováno v:
SLAS Technology, Vol 27, Iss 1, Pp 76-84 (2022)
The advent of deep-learning has set new standards in an array of image translation applications. At present, the use of these methods often requires computer programming experience. Non-commercial programs with graphical interface usually do not allo
Externí odkaz:
https://doaj.org/article/4024083413b74372b49c128f26c2cd74
Autor:
Thomas Grenier-Larouche, Lydia Coulter Kwee, Yann Deleye, Paola Leon-Mimila, Jacquelyn M. Walejko, Robert W. McGarrah, Simon Marceau, Sylvain Trahan, Christine Racine, André C. Carpentier, Aldons J. Lusis, Olga Ilkayeva, Marie-Claude Vohl, Adriana Huertas-Vazquez, André Tchernof, Svati H. Shah, Christopher B. Newgard, Phillip J. White
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Hepatic de novo lipogenesis is influenced by the branched-chain α-keto acid dehydrogenase (BCKDH) kinase (BCKDK). Here, we aimed to determine whether circulating levels of the immediate substrates of BCKDH, the branched-chain α-keto acids (BCKAs),
Externí odkaz:
https://doaj.org/article/6137ea5ab08f4f1cb6e623ab02150e6f
Autor:
Anne-Sophie Brazeau, Virginie Messier, Meryem K. Talbo, Claudia Gagnon, Nadine Taleb, Isabel Fortier, Zekai Wu, Bruce A. Perkins, André C. Carpentier, Aude Bandini, Rémi Rabasa-Lhoret
Publikováno v:
Canadian Journal of Diabetes. 46:813-821
The BETTER (BEhaviors, Therapies, TEchnologies and hypoglycemic Risk in Type 1 diabetes) registry is a type 1 diabetes population surveillance system codeveloped with patient partners to address the burden of hypoglycemia and assess the impact of new
Autor:
Monika Kastner, Julie Makarski, M. Bianca Seaton, Kimia Sedig, Mathieu Bélanger, André C. Carpentier, André Gaudreau, Gloria Lourido, Michelle Murray, Katie N. Dainty
Publikováno v:
Canadian Journal of Diabetes. 46:776-788
The Diabetes Action Canada Training and Mentoring (DAC-TM) Program launched in June 2017, with the goal of building capacity in the next generation of diabetes researchers in Canada in patient-oriented research (POR).We conducted a program evaluation
Publikováno v:
Endocrine Reviews. 44:143-192
Brown adipose tissue (BAT) displays the unique capacity to generate heat through uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for cardiometabolic diseases. Here, we review BAT cellular metabolism, its regulat
Publikováno v:
Journal of the American College of Cardiology. 78:513-531
Obesity contributes to reduced life expectancy because of its link with type 2 diabetes and cardiovascular disease. Yet, targeting this poorly diagnosed, ill-defined, and underaddressed modifiable risk factor remains a challenge. In this review, we e