Zobrazeno 1 - 10
of 17
pro vyhledávání: '"André A. Fernandez"'
Autor:
Érico Induzzi Borges, André Lopez Fernandez, Louis Fernando Marques de Almeida, Rebecca Vieira Teixeira, Herval Ribeiro Soares Neto, Sônia Maria Cesar de Azevedo Silva
Publikováno v:
São Paulo Medical Journal.
Context: Syphilis is a pleomorphic, insidious disease and an important differential diagnosis of ocular and CNS involvement. Its recognition and treatment are extremely important, given the high morbidity of its natural history. Case report: A 79-yea
Autor:
Érico Induzzi Borges, André Lopez Fernandez, Louis Fernando Marques de Almeida, Juline do Prado Paes, Jandey da Glória Bigonha, Antônio José da Rocha, Herval Soares Ribeiro Neto, Sônia Maria Cesar de Azevedo Silva
Publikováno v:
São Paulo Medical Journal.
Context: PML is a dymyeliniating disease of the brain, caused by JC virus infection reactivation in immunocompromised patients, especially by AIDS, hematological disease and immunosuppressive therapies. Case report: A 67-year-old woman was diagnosed
Autor:
Ledy H.S. Oliveira, André P. Fernandez, Brunno L.S. Xavier, Eliane V.M. Rodrigues, José A.S. Pantaleão, Silvia M.B. Cavalcanti
Publikováno v:
DST, Vol 13, Iss 2 (2001)
O gene supressor de tumor p53 expressa uma proteína que atua como regulador negativo do ciclo celular quando ocorre uma lesão no DNA. Alterações nesta proteína por mutação do gene ou por inativação por proteínas virais podem contribuir para
Externí odkaz:
https://doaj.org/article/e4cefa89d62e459296c75d61dc996519
Publikováno v:
Photochemistry and Photobiology. 91:486-492
The fish genus Xiphophorus consists of 26 species distributed along the eastern slopes of mountain ranges extending from northern Mexico to Belize and Nicaragua. We analyzed light-dependent repair of UV-induced DNA damage in at least two species from
Publikováno v:
Photochemistry and Photobiology. 87:335-341
Nucleotide excision repair (NER) is the primary defense against the DNA damage implicit in skin cancer formation and is negatively affected by chronic exposure to UVB radiation. However, in-situ and in-vitro studies consistently yield equivocal resul
Autor:
David L. Mitchell, André A. Fernandez
Publikováno v:
Pigment Cell & Melanoma Research. 24:119-124
The relationship between DNA damage, mutations and the initiation and progression of sunlight-induced melanoma has not yet been resolved. Recently, it has become apparent that the etiology of sunlight-induced melanoma is fundamentally different from
Autor:
Paul R. Bowser, André A. Fernandez
Publikováno v:
Molecular Ecology. 19:3114-3123
Adult height is a risk factor in numerous human cancers that involve aberrant receptor tyrosine kinase (RTK) signalling. However, its importance is debated due to conflicting epidemiological studies and the lack of useful in vivo models. In Xiphophor
Autor:
André A. Fernandez, David Trono, Irma B. Gimenez-Conti, Lakshmi Paniker, Howard D. Thames, David L. Mitchell, Rachel Garcia, Rodney S. Nairn
Publikováno v:
Proceedings of the National Academy of Sciences. 107:9329-9334
We examined the wavelength dependence of ultraviolet (UV) ra-diation (UVR)-induced melanoma in a Xiphophorus backcross hybrid model previously reported to be susceptible to melanoma induction by ultraviolet A (UVA) and visible light. Whereas ultravio
Autor:
David L. Mitchell, André A. Fernandez, Mark Nuttall, Herng Hsiang Lo, Lakshmi Paniker, Matthew May, Maria D. Person, Kevin Lin, Ryan L. Earley, Rachel Garcia, Kyle Zigelsky, Amanda F. Hanninen
Publikováno v:
Pigment cellmelanoma research. 27(3)
Using the Xiphophorus fish melanoma model, we show a strong male bias for sunlight-induced malignant melanoma, consistent with that seen in the human population. To examine underlying factors, we exposed adult X. couchianus fish to a single, subletha
Autor:
David L. Mitchell, André A. Fernandez
Publikováno v:
Photochemicalphotobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 11(1)
Ultraviolet radiation is responsible for melanoma. In this review, we address the role of the different UV spectra in melanoma. The data suggest that only UVB is capable of initiating melanoma, and that both UVA and UVB are involved in the progressio