Zobrazeno 1 - 10
of 29
pro vyhledávání: '"André Warnecke"'
Publikováno v:
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 49(2)
Background Worldwide, consistent survival benefit for chemotherapy in hepatocellular carcinoma (HCC) is a golden goal for concerned researchers. Nexavar® (sorafenib) is the only approved agent that achieved touchable successes in this regard. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e29d79659410433b5933fe8f9c336e4
https://pubmed.ncbi.nlm.nih.gov/27825923
https://pubmed.ncbi.nlm.nih.gov/27825923
Autor:
André Warnecke
Publikováno v:
Drug Delivery in Oncology: From Basic Research to Cancer Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459e3a50e9123f01bb9eee6b9713a9ad
https://doi.org/10.1002/9783527634057.ch19
https://doi.org/10.1002/9783527634057.ch19
Publikováno v:
Tetrahedron Letters. 51:4371-4374
A number of novel acid-sensitive Schiff bases derived from p-aminobenzyl alcohol and various benzaldehyde derivatives were synthesized and were subsequently shown to trigger benzyl elimination reactions. The kinetics of acid-catalyzed hydrolysis at p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c85267e9928fca49251c9374717ac0d
https://doi.org/10.1016/j.tetlet.2010.06.055
https://doi.org/10.1016/j.tetlet.2010.06.055
Autor:
Peter Hauff, Ying Luo, Shangjie Xu, Kai Licha, Ralph Graeser, Felix Kratz, André Warnecke, Rainer Haag
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1030-1034
In this paper new dendritic core-shell architectures with pH-labile linkers based on hyperbranched polyglycerol cores and biocompatible poly(ethylene glycol) shells were synthesized which encapsulate the anticancer agent doxorubicin and a dye for nea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0325d6c2e63f3e21716db6593a4af5d
https://doi.org/10.1016/j.bmcl.2008.01.043
https://doi.org/10.1016/j.bmcl.2008.01.043
Publikováno v:
Journal of Controlled Release. 131:100-106
The development of resistance is one of the major limitations for the use of platinum (Pt) complexes in cancer chemotherapy. As reduced cellular uptake is a well-known resistance mechanism of cisplatin we explored the potential to overcome resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6b4eeea31ce6ed78fbba75add5120d
https://doi.org/10.1016/j.jconrel.2008.07.017
https://doi.org/10.1016/j.jconrel.2008.07.017
Autor:
Felix Kratz, André Warnecke
Publikováno v:
Bioconjugate Chemistry. 14:377-387
In situ binding of thiol-reactive prodrugs to the cysteine-34 position of circulating albumin is a new approach in drug delivery. Therefore, five maleimide-bearing derivatives of the anticancer drug camptothecin (CPT) were developed as albumin-bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6238eba2da4ea4019a92af26b6e32522
https://doi.org/10.1021/bc0256289
https://doi.org/10.1021/bc0256289
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :1199-1202
We report the synthesis of derivatives of vitamin K3 as well as of vitamins K1 and K2 containing a different number of methyl groups in various positions in order to reduce their redox potentials and to change systematically their steric features. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8c65b10b805fa9d5f15caecadc467a5
https://doi.org/10.1039/a900190e
https://doi.org/10.1039/a900190e
Autor:
Herbert Plenio, André Warnecke
Publikováno v:
Journal of Organometallic Chemistry. 544:133-137
The reactions of the lithiated trialkylsiloxy-cyclopentadienyl ethers (C 5 H 4 OSiR 3 R 3 Et 3 , Me 2 1 Bu, 1 Pr 3 ) with TiCl 4 , ZrCl 4 , Cp ∗ ZrCl 3 or CpTiCl 3 result in the formation of the respective metallocene dichlorides [(C 5 H 4 OSiR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::562451f5cb920e9549baef32d504df20
https://doi.org/10.1016/s0022-328x(97)00325-2
https://doi.org/10.1016/s0022-328x(97)00325-2
Autor:
Felix Kratz, Friederike I. Nollmann, Olga Fuchs, Koester Stephan David, Simon Waltzer, André Warnecke, Khalid Abu Ajaj
Publikováno v:
Cancer Research. 76:4858-4858
Drug delivery systems in oncology for treating cancer are based on different drug release mechanisms at the tumor site including primarily hydrolytic, reductive, enzymatic and/or acid-sensitive cleavage. Drug carrier conjugates that incorporate an ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fa0e7d0788ff40609b5734034f389c
https://doi.org/10.1158/1538-7445.am2016-4858
https://doi.org/10.1158/1538-7445.am2016-4858
Publikováno v:
International journal of pharmaceutics. 441(1-2)
In this work, we evaluated combinations of doxorubicin with INNO-206, a (6-maleimidocaproyl)hydrazone derivative of doxorubicin (DOXO-EMCH) that is currently undergoing two phase II clinical trials, in a primarily chemoresistant tumor indication, i.e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189754b1d08db618616a0bff9d77567d
https://pubmed.ncbi.nlm.nih.gov/23149257
https://pubmed.ncbi.nlm.nih.gov/23149257