Zobrazeno 1 - 10
of 389
pro vyhledávání: '"André, Tchernof"'
Publikováno v:
BMC Endocrine Disorders, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background A better understanding of adipose tissue (AT) dysfunction, which includes morphological and functional changes such as adipocyte hypertrophy as well as impaired adipogenesis, lipid storage/mobilization, endocrine and inflammatory
Externí odkaz:
https://doaj.org/article/35478226de3e4c4eb2f643314cded85b
Autor:
Marianne Côté, Laurence Pelletier, Mélanie Nadeau, Léonie Bouvet-Bouchard, François Julien, Andréanne Michaud, Laurent Biertho, André Tchernof
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundAmong commonly performed bariatric surgeries, biliopancreatic diversion with duodenal switch (BPD-DS) provides greater weight loss than Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG), with sustained metabolic improvements. Howev
Externí odkaz:
https://doaj.org/article/4b634eb0707e456eb2b51389ed8bbfff
Autor:
Run Zhou Ye, Emilie Montastier, Frédérique Frisch, Christophe Noll, Hugues Allard-Chamard, Nicolas Gévry, André Tchernof, André C. Carpentier
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108692- (2024)
Summary: Adipocyte hypertrophy is associated with metabolic complications independent of obesity. We aimed to determine: 1) the association between adipocyte size and postprandial fatty acid metabolism; 2) the potential mechanisms driving the obesity
Externí odkaz:
https://doaj.org/article/679ccead7b3043cbb1c81f76245c3683
Autor:
Eve-Julie Tremblay, André Tchernof, Mélissa Pelletier, Nicolas Chabot, Denis R. Joanisse, Pascale Mauriège
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 175-189 (2022)
Adipose tissue (AT) dysfunctions, such as adipocyte hypertrophy, macrophage infiltration and secretory adiposopathy (low plasma adiponectin/leptin, A/L, ratio), associate with metabolic disorders. However, no study has compared the relative contribut
Externí odkaz:
https://doaj.org/article/29bf7e91b10b4ae0aa5849655e8089db
Autor:
Eloi Gagnon, William Pelletier, Émilie Gobeil, Jérôme Bourgault, Hasanga D. Manikpurage, Ina Maltais-Payette, Erik Abner, Nele Taba, Tõnu Esko, Patricia L. Mitchell, Nooshin Ghodsian, Jean-Pierre Després, Marie-Claude Vohl, André Tchernof, Sébastien Thériault, Benoit J. Arsenault
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-9 (2022)
Gagnon et al. perform a Mendelian randomization study to investigate whether excess liver fat underpins adiposity’s effect on cardiometabolic disease risk. They show that abdominal adiposity strongly increases disease risk independently of liver fa
Externí odkaz:
https://doaj.org/article/1e515edb333a4daa9d17086f57f33806
Autor:
Annie Bouchard-Mercier, Juan de Toro-Martín, Mélanie Nadeau, Odette Lescelleur, Stéfane Lebel, Denis Richard, Laurent Biertho, André Tchernof, Marie-Claude Vohl
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Bariatric surgery is an effective therapy for individuals with severe obesity to achieve sustainable weight loss and to reduce comorbidities. Examining the molecular signature of subcutaneous adipose tissue (SAT) following differe
Externí odkaz:
https://doaj.org/article/04380e1025b54e0d86ae4dbf6c5712c3
Autor:
Yashar Zeighami, Mahsa Dadar, Justine Daoust, Mélissa Pelletier, Laurent Biertho, Léonie Bouvet-Bouchard, Stephanie Fulton, André Tchernof, Alain Dagher, Denis Richard, Alan Evans, Andréanne Michaud
Publikováno v:
NeuroImage, Vol 259, Iss , Pp 119415- (2022)
Individuals living with obesity tend to have increased brain age, reflecting poorer brain health likely due to grey and white matter atrophy related to obesity. However, it is unclear if older brain age associated with obesity can be reversed followi
Externí odkaz:
https://doaj.org/article/8b20184367a248cc85dc5cdda16f7856
Autor:
Aurélie Baillot, Maxime St-Pierre, Josyanne Lapointe, Paquito Bernard, Dale Bond, Ahmed Jérôme Romain, Pierre Y Garneau, Laurent Biertho, André Tchernof, Patricia Blackburn, Marie-France Langlois, Jennifer Brunet
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 9, p e39633 (2022)
BackgroundRegular physical activity (PA) is recommended to optimize weight and health outcomes in patients who have undergone metabolic and bariatric surgery (MBS). However, >70% of patients have low PA levels before MBS that persist after MBS. Altho
Externí odkaz:
https://doaj.org/article/71150857b6cd46bd964cd429adae56c4
Autor:
Thomas Grenier-Larouche, Lydia Coulter Kwee, Yann Deleye, Paola Leon-Mimila, Jacquelyn M. Walejko, Robert W. McGarrah, Simon Marceau, Sylvain Trahan, Christine Racine, André C. Carpentier, Aldons J. Lusis, Olga Ilkayeva, Marie-Claude Vohl, Adriana Huertas-Vazquez, André Tchernof, Svati H. Shah, Christopher B. Newgard, Phillip J. White
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Hepatic de novo lipogenesis is influenced by the branched-chain α-keto acid dehydrogenase (BCKDH) kinase (BCKDK). Here, we aimed to determine whether circulating levels of the immediate substrates of BCKDH, the branched-chain α-keto acids (BCKAs),
Externí odkaz:
https://doaj.org/article/6137ea5ab08f4f1cb6e623ab02150e6f
Autor:
Ina Maltais-Payette, Fannie Lajeunesse-Trempe, Philippe Pibarot, Laurent Biertho, André Tchernof
Publikováno v:
Metabolites, Vol 13, Iss 2, p 201 (2023)
The severity of the symptoms associated with COVID-19 is highly variable, and has been associated with circulating amino acids as a group of analytes in metabolomic studies. However, for each individual amino acid, there are discordant results among
Externí odkaz:
https://doaj.org/article/6c61ebccb88847feb21c42eced686ae3