Zobrazeno 1 - 10
of 167
pro vyhledávání: '"André, Mann"'
Autor:
Elodie Dupuis, Candide Hounsou, Vincent Gasparik, Jean-Philippe Pin, Denis Heissler, Doria Alili, Abderazak Belhocine, Thierry Durroux, Corinne Baehr, Marcel Hibert, André Mann, Dominique Bonnet, Thomas Roux, Thiéric Rodriguez
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 61 (1), pp.174-188. ⟨10.1021/ACS.JMEDCHEM.7B01220⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 61 (1), pp.174-188. ⟨10.1021/ACS.JMEDCHEM.7B01220⟩
Monoamine neurotransmitters such as serotonin, dopamine, histamine, and noradrenaline have important and varied physiological functions and similar chemical structures. Representing important pharmaceutical drug targets, the corresponding G-protein-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ca155c5fb3560ebce588fcfb140fcf
https://hal.archives-ouvertes.fr/hal-02366277
https://hal.archives-ouvertes.fr/hal-02366277
Autor:
Martial, Ruat, Hélène, Faure, Elisabeth, Traiffort, Angèle, Schoenfelder, André, Mann, Taddei, Maurizio, Antonio, Solinas, Manetti, Fabrizio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0ad0dca52ba229385e06db323af5dd0f
http://hdl.handle.net/11365/1013586
http://hdl.handle.net/11365/1013586
Autor:
Tatiana Gorojankina, Lucile Hoch, André Mann, Fabrizio Manetti, Annalisa Gabrielli, Laurent Brasseur, Elena Petricci, Martial Ruat, Hélène Faure, Maurizio Taddei
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2016, 121, pp.747-57. ⟨10.1016/j.ejmech.2016.05.062⟩
European Journal of Medicinal Chemistry, Elsevier, 2016, 121, pp.747-57. ⟨10.1016/j.ejmech.2016.05.062⟩
International audience; Smoothened (Smo) is the signal transducer of the Hedgehog (Hh) pathway and its stimulation is considered a potential powerful tool in regenerative medicine to treat severe tissue injuries. Starting from GSA-10, a recently repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a412eb236a16bc3bb7c906e42fc0cf
https://hal.archives-ouvertes.fr/hal-01366729
https://hal.archives-ouvertes.fr/hal-01366729
Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway
Autor:
Elena Petricci, Fabrizio Manetti, Soazig Le Lay, Lucile Hoch, André Mann, Hélène Faure, Audrey Fleury, Nicolas Girard, Maurizio Taddei, M. Carmen Martinez, Jérôme Larghero, Ramaroson Andriantsitohaina, Caroline Jacques, Martial Ruat
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6, pp.23479. ⟨10.1038/srep23479⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.23479. 〈10.1038/srep23479〉
Scientific Reports, Nature Publishing Group, 2016, 6, pp.23479. ⟨10.1038/srep23479⟩
Scientific Reports, Nature Publishing Group, 2016, 6, pp.23479. 〈10.1038/srep23479〉
Hedgehog (Hh) is a critical regulator of adipogenesis. Extracellular vesicles are natural Hh carriers, as illustrated by activated/apoptotic lymphocytes specifically shedding microparticles (MP) bearing the morphogen (MPHh+). We show that MPHh+ inhib
Autor:
Martial, Ruat, Hélène, Faure, Elisabeth, Traiffort, Hermine, Roudaut, André, Mann, Angèle, Schoenfelder, Taddei, Maurizio, Manetti, Fabrizio, Antonio, Solinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1820::bf8a696044bc2e1711422d094c381da1
http://hdl.handle.net/11365/1011111
http://hdl.handle.net/11365/1011111
Autor:
Martial, Ruat, Hélène, Faure, Elisabeth, Traiffort, Angèle, Schoenfelder, André, Mann, Taddei, Maurizio, Antonio, Solinas, Manetti, Fabrizio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1820::8808f58cdfb6daf195bfc2069d2c6450
http://hdl.handle.net/11365/1011108
http://hdl.handle.net/11365/1011108
Autor:
Hermine Roudaut, André Mann, Fabrizio Manetti, Hélène Faure, Elisabeth Traiffort, Antonio Solinas, Angèle Schoenfelder, Martial Ruat, Maurizio Taddei
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2012, 55 (4), pp.1559-71. ⟨10.1021/jm2013369⟩
Journal of Medicinal Chemistry, American Chemical Society, 2012, 55 (4), pp.1559-71. ⟨10.1021/jm2013369⟩
International audience; The Smoothened (Smo) receptor is the major transducer of the Hedgehog (Hh) signaling pathway. On the basis of the structure of the acylthiourea Smo antagonist (MRT-10), a number of different series of analogous compounds were
Publikováno v:
European Journal of Organic Chemistry. 2011:6409-6412
An expeditious route to (±)-desethyleburnamonine (1), a direct precursor of vindeburnol, is reported. Microwave irradiation of an indolo-tetrahydropyridine ethyl ester 2 in CH3CN in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) gave the p
Publikováno v:
Synlett. 2011:199-202
Hydroformylation is a powerful reaction that has suffered for some negative prejudices related to the use of gaseous H 2 and CO. Now it is possible to carry out hydroformylation and different cyclohydrocarbonylations, even on complex substrates, usin
Publikováno v:
European Journal of Organic Chemistry. 2010:6005-6018
S N 2' sequences have been employed for the synthesis of β-branched α-amino acids using 1,2-diastereocontrol for forming C―C bonds. An oxazolidine fragment derived from Garner's aldehyde provides the handle for facial discrimination and acts as a