Zobrazeno 1 - 10
of 124
pro vyhledávání: '"András Spät"'
Autor:
Gergő Szanda, Tony Jourdan, Éva Wisniewski, Resat Cinar, Grzegorz Godlewski, Anikó Rajki, Jie Liu, Lee Chedester, Bence Szalai, András Dávid Tóth, Eszter Soltész-Katona, László Hunyady, Asuka Inoue, Viktória Bea Horváth, András Spät, Joseph Tam, George Kunos
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107207- (2023)
Summary: Molecular interactions between anorexigenic leptin and orexigenic endocannabinoids, although of great metabolic significance, are not well understood. We report here that hypothalamic STAT3 signaling in mice, initiated by physiological eleva
Externí odkaz:
https://doaj.org/article/fdec89d7da924457af4fc198282c561d
Publikováno v:
Artery Research, Vol 25, Iss 1 (2020)
Elevation of plasma [K+] and [angiotensin II] (Ang II), two major physiological stimuli of adrenal zona glomerulosa cells, increase aldosterone production by triggering cytosolic Ca2+ signalling. Cytosolic Ca2+ signals are accompanied by mitochondria
Externí odkaz:
https://doaj.org/article/ea34bea11d204d42925ad1cd920f023c
Autor:
Melanie Paillard, György Csordás, Gergö Szanda, Tünde Golenár, Valentina Debattisti, Adam Bartok, Nadan Wang, Cynthia Moffat, Erin L. Seifert, András Spät, György Hajnóczky
Publikováno v:
Cell Reports, Vol 18, Iss 10, Pp 2291-2300 (2017)
Mitochondrial Ca2+ uptake through the Ca2+ uniporter supports cell functions, including oxidative metabolism, while meeting tissue-specific calcium signaling patterns and energy needs. The molecular mechanisms underlying tissue-specific control of th
Externí odkaz:
https://doaj.org/article/74bcc08031334f4fbefb96b73971341a
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25199 (2011)
The dynamin-related GTPase protein OPA1, localized in the intermembrane space and tethered to the inner membrane of mitochondria, participates in the fusion of these organelles. Its mutation is the most prevalent cause of Autosomal Dominant Optic Atr
Externí odkaz:
https://doaj.org/article/b8ffcdf650aa4591b84f20ad60436973
Autor:
Gergő Szanda, András Spät
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 470:1141-1148
The biological effects of physiological stimuli of adrenocortical glomerulosa cells are predominantly mediated by the Ca2+ and the cAMP signal transduction pathways. The complex interplay between these signalling systems fine-tunes aldosterone secret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29994de08b1e1c90b7aa5d4828052aab
https://doi.org/10.1007/s00424-018-2157-5
https://doi.org/10.1007/s00424-018-2157-5
Autor:
András, Spät, Gergő, Szanda
Publikováno v:
Pflugers Archiv : European journal of physiology. 470(8)
The biological effects of physiological stimuli of adrenocortical glomerulosa cells are predominantly mediated by the Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d057a9a11a98a971502e2a19b8887cc5
https://pubmed.ncbi.nlm.nih.gov/29876637
https://pubmed.ncbi.nlm.nih.gov/29876637
Publikováno v:
Journal of cell science. 131(10)
We have previously demonstrated in H295R adrenocortical cells that the Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aaa15f09eda81ce30cd493a197df388a
https://pubmed.ncbi.nlm.nih.gov/29661848
https://pubmed.ncbi.nlm.nih.gov/29661848
Mitochondrial cAMP exerts positive feedback on mitochondrial Ca2+ uptake via the recruitment of Epac
Publikováno v:
Journal of Cell Science.
We have previously demonstrated in H295R adrenocortical cells that the Ca2+-dependent production of mitochondrial cAMP (mt-cAMP) by the matrix soluble adenylyl cyclase (sAC; encoded by ADCY10) is associated with enhanced aldosterone production. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5154117fcfe8028c592bf7b1bf5ace59
https://doi.org/10.1242/jcs.215178
https://doi.org/10.1242/jcs.215178
Publikováno v:
Cell Calcium. 57:49-55
The most frequent form of hereditary blindness, autosomal dominant optic atrophy (ADOA), is caused by the mutation of the mitochondrial protein Opa1 and the ensuing degeneration of retinal ganglion cells. Previously we found that knockdown of OPA1 en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02805f0a0a147bface6c64323c7b44ae
https://doi.org/10.1016/j.ceca.2014.11.008
https://doi.org/10.1016/j.ceca.2014.11.008
Autor:
András, Spät, Gergö, Szanda
Publikováno v:
Advances in experimental medicine and biology. 993
Mitochondria extensively modify virtually all cellular Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53fbcf020307217eec6146228980495f
https://pubmed.ncbi.nlm.nih.gov/28900919
https://pubmed.ncbi.nlm.nih.gov/28900919